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Sera PrognosticsSERA -5.96%69 Return-on-Tangible-Asset is -34.69% as of Mar. 2026. GuruFocus rates SERA with a GF Score™ of 69/100 and a GF Value™ of $1.83 (Modestly Overvalued). The stock has 5 warning signs investors should review. Among 855 Medical Devices & Instruments companies, Sera Prognostics ranks worse than 76.02% on this metric.
Return-on-Tangible-Asset is calculated as Net Income divided by its average total tangible assets. Total tangible assets equals to Total Assets minus Intangible Assets. Sera Prognostics's annualizedNet Income for the quarter that ended in Mar. 2026 was $-33.60 Mil. Sera Prognostics's average total tangible assets for the quarter that ended in Mar. 2026 was $96.84 Mil. Therefore, Sera Prognostics's annualized Return-on-Tangible-Asset for the quarter that ended in Mar. 2026 was -34.69%.
The historical rank and industry rank for Sera Prognostics's Return-on-Tangible-Asset or its related term are showing as below:
SERA'
s Return-on-Tangible-Asset Range Over the Past 10 Years
Min: -104.31 Med: -39.4 Max: -30.38
Current: -30.38
During the past 7 years, Sera Prognostics's highest Return-on-Tangible-Asset was -30.38%. The lowest was -104.31%. And the median was -39.40%.
SERA's Return-on-Tangible-Asset is ranked worse than 76.02% of 855
companies
in the Medical Devices & Instruments industry
Industry Median: 0.62
vs SERA: -30.38
Sera Prognostics (NAS:SERA) Return-on-Tangible-Asset Explanation
Return-on-Tangible-Asset measures the rate of return on the average total tangible assets (total assets minus intangible assets). Tangible means physical in nature. Intangible Assets are assets that are not physical in nature, and typically "derive their value from legal or intellectual rights." Return-on-Tangible-Asset measures a firm's efficiency at generating profits from its tangible assets. It shows how well a company uses what it has to generate earnings. Return-on-Tangible-Assets can vary drastically across industries. Therefore, Return-on-Tangible-Asset should not be used to compare companies in different industries.
Be Aware
Like ROE and ROA, Return-on-Tangible-Asset is calculated with only 12 months data. Fluctuations in the companys earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. Return-on-Tangible-Asset can be affected by events such as stock buyback or issuance, and by a companys tax rate and its interest payment. Return-on-Tangible-Asset may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).
Many analysts argue the higher return the better. Buffett states that really high Return-on-Tangible-Asset may indicate vulnerability in the durability of the competitive advantage.
Sera Prognostics Return-on-Tangible-Asset Related Terms
Sera Prognostics Return-on-Tangible-Asset Historical Data
* Premium members only.
The historical data trend for Sera Prognostics's Return-on-Tangible-Asset can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
SERA vs LNSR, ECOR, SNWV: Return-on-Tangible-Asset Comparison
For the Medical Devices subindustry, Sera Prognostics's Return-on-Tangible-Asset, along with its competitors' market caps and Return-on-Tangible-Asset data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Sera Prognostics Return-on-Tangible-Asset vs Medical Devices & Instruments Industry
For the Medical Devices & Instruments industry and Healthcare sector, Sera Prognostics's Return-on-Tangible-Asset distribution charts can be found below:
* The bar in red indicates where Sera Prognostics's Return-on-Tangible-Asset falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual Return-on-Tangible-Asset, the net income of the last fiscal year and the average total tangible assets over the fiscal year are used. In calculating the quarterly data,
the Net Income data used here is four times the quarterly (Mar. 2026) net income data.
What does a Return-on-Tangible-Asset of -34.69% mean?
Sera Prognostics (SERA) has a Return-on-Tangible-Asset of -34.69% as of Mar. 2026. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on Sera Prognostics and its competitors. According to the industry distribution chart, Sera Prognostics ranks #650 out of 855 companies in the Medical Devices & Instruments industry, placing it in the top 76%.
Is Sera Prognostics' Return-on-Tangible-Asset too high?
Sera Prognostics' current Return-on-Tangible-Asset is -34.69%. Based on the distribution chart, Sera Prognostics ranks #650 out of 855 companies in the Medical Devices & Instruments industry, which is in the bottom quartile relative to peers. Overall, Sera Prognostics has a GF Score™ of 69/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Sera Prognostics' Return-on-Tangible-Asset compare to LNSR and ECOR?
According to the Medical Devices & Instruments industry distribution chart, Sera Prognostics ranks #650 out of 855 companies for Return-on-Tangible-Asset. This places Sera Prognostics in the lower half of its industry. The industry median Return-on-Tangible-Asset is 0.62. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Asset for a Medical Devices & Instruments company?
The median Return-on-Tangible-Asset among Medical Devices & Instruments companies is 0.62, based on 855 companies in the industry. Companies in the top quartile (top 25%) have a Return-on-Tangible-Asset significantly above this median, while those in the bottom quartile fall well below. However, Return-on-Tangible-Asset should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Asset mean?
A high Return-on-Tangible-Asset can signal that a stock is expensive relative to its fundamentals. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on Sera Prognostics and its competitors. For the Medical Devices & Instruments industry, the median Return-on-Tangible-Asset is 0.62 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Sera Prognostics's current Return-on-Tangible-Asset is -34.69%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Sera Prognostics stock overvalued right now?
Based on GuruFocus' analysis, Sera Prognostics (SERA) is currently considered Modestly Overvalued. The stock's GF Value™ is $1.83, compared to a current price of $2.05 — trading 12% above its estimated fair value. The current Return-on-Tangible-Asset is -34.69%. Sera Prognostics' overall GF Score™ is 69/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Asset calculated?
Return-on-Tangible-Asset is calculated from a company's financial statements. For Sera Prognostics (SERA), the current Return-on-Tangible-Asset is -34.69% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Sera Prognostics (SERA) Overvalued in 2026?
Based on GuruFocus' analysis, Sera Prognostics stock appears to be overvalued.
The current stock price of $2.05 is trading 12% above its estimated GF Value™ of $1.83.
GuruFocus considers Sera Prognostics to be Modestly Overvalued.
Key valuation signals for SERA:
Return-on-Tangible-Asset: -34.69%
GF Value™: $1.83 vs. price of $2.05 (12% above fair value)
No single metric tells the full story. See the SERA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Sera Prognostics Inc is a health diagnostic company. It is a women's health company utilizing the proprietary proteomics and bioinformatics platform, and data resources to improve maternal and neonatal health by discovering, developing, and commercializing blood-based biomarker tests, and predictive analytic products and services. The Company operates as one operating segment, which is developing and commercializing its medical diagnostic products and services.
69GF Score
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