Biomea FusionBMEA +2.53%31 Return-on-Tangible-Equity is -205.76% as of Mar. 2026. GuruFocus rates BMEA with a GF Score™ of 31/100. The stock has 1 warning sign investors should review. Among 1,195 Biotechnology companies, Biomea Fusion ranks worse than 84.6% on this metric.
Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. Biomea Fusion's annualized net income for the quarter that ended in Mar. 2026 was $-49.66 Mil. Biomea Fusion's average shareholder tangible equity for the quarter that ended in Mar. 2026 was $24.14 Mil. Therefore, Biomea Fusion's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 was -205.76%.
The historical rank and industry rank for Biomea Fusion's Return-on-Tangible-Equity or its related term are showing as below:
BMEA'
s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: -206.84 Med: -104.9 Max: -45.19
Current: -187.08
During the past 7 years, Biomea Fusion's highest Return-on-Tangible-Equity was -45.19%. The lowest was -206.84%. And the median was -104.90%.
BMEA's Return-on-Tangible-Equity is ranked worse than 84.6% of 1195
companies
in the Biotechnology industry
Industry Median: -42.21
vs BMEA: -187.08
Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.
Be Aware
Net Income is used.
Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.
Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.
Biomea Fusion Return-on-Tangible-Equity Related Terms
Biomea Fusion Return-on-Tangible-Equity Historical Data
* Premium members only.
The historical data trend for Biomea Fusion's Return-on-Tangible-Equity can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
BMEA vs ANIX, PMN, ATRA: Return-on-Tangible-Equity Comparison
For the Biotechnology subindustry, Biomea Fusion's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Biomea Fusion Return-on-Tangible-Equity vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Biomea Fusion's Return-on-Tangible-Equity distribution charts can be found below:
* The bar in red indicates where Biomea Fusion's Return-on-Tangible-Equity falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data,
the net income data used here is four times the quarterly (Mar. 2026) net income data.
Return-on-Tangible-Equity is displayed in the 10-year financial page.
What does a Return-on-Tangible-Equity of -205.76% mean?
Biomea Fusion (BMEA) has a Return-on-Tangible-Equity of -205.76% as of Mar. 2026. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Biomea Fusion and its competitors. According to the industry distribution chart, Biomea Fusion ranks #1011 out of 1195 companies in the Biotechnology industry, placing it in the top 84.6%.
Is Biomea Fusion's Return-on-Tangible-Equity too high?
Biomea Fusion's current Return-on-Tangible-Equity is -205.76%. Based on the distribution chart, Biomea Fusion ranks #1011 out of 1195 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Biomea Fusion has a GF Score™ of 31/100, reflecting its overall financial health beyond just this single metric.
How does Biomea Fusion's Return-on-Tangible-Equity compare to ANIX and PMN?
According to the Biotechnology industry distribution chart, Biomea Fusion ranks #1011 out of 1195 companies for Return-on-Tangible-Equity. This places Biomea Fusion in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Biomea Fusion and its competitors. Biomea Fusion's current Return-on-Tangible-Equity is -205.76%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Biomea Fusion stock overvalued right now?
Biomea Fusion (BMEA) has a current Return-on-Tangible-Equity of -205.76%. The current Return-on-Tangible-Equity is -205.76%. Biomea Fusion's overall GF Score™ is 31/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For Biomea Fusion (BMEA), the current Return-on-Tangible-Equity is -205.76% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Biomea Fusion Inc is a a clinical stage diabetes and obesity medicines company focused on the discovery and development of oral, small molecule drugs to treat and improve the lives of patients with diabetes, obesity, and other metabolic diseases. It operate as an organization centered on two of its core drug candidate development programs: (i) icovamenib, its clinical program's drug candidate, currently being developed as an orally bioavailable, and selective, covalent inhibitor of menin in two clinical and multiple preclinical studies, investigating icovamenib's potential in type 1 and type 2 diabetes, as well as its impact in obesity, and (ii) BMF-650, its investigational, next-generation oral glucagon-like peptide-1 GLP-1 receptor agonist in development for the treatment of obesity.
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