GRI (GRI Bio) Return-on-Tangible-Equity: -96.56% (As of Mar. 2026)

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GRI GRI Bio Inc GRI
33 GF Score
Price $1.72
! 1 Warning Sign
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What is GRI Bio Return-on-Tangible-Equity?

GRI Bio GRI -1.16% 33 Return-on-Tangible-Equity is -96.56% as of Mar. 2026. GuruFocus rates GRI with a GF Score™ of 33/100. The stock has 1 warning sign investors should review. Among 1,198 Biotechnology companies, GRI Bio ranks worse than 88.48% on this metric.

Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. GRI Bio's annualized net income for the quarter that ended in Mar. 2026 was $-7.99 Mil. GRI Bio's average shareholder tangible equity for the quarter that ended in Mar. 2026 was $8.28 Mil. Therefore, GRI Bio's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 was -96.56%.

The historical rank and industry rank for GRI Bio's Return-on-Tangible-Equity or its related term are showing as below:

GRI' s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: -382.52   Med: -310.35   Max: -236.38
Current: -236.38

During the past 5 years, GRI Bio's highest Return-on-Tangible-Equity was -236.38%. The lowest was -382.52%. And the median was -310.35%.

GRI's Return-on-Tangible-Equity is ranked worse than
88.48% of 1198 companies
in the Biotechnology industry
Industry Median: -42.355 vs GRI: -236.38

GRI Bio  (NAS:GRI) Return-on-Tangible-Equity Explanation

Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.


Be Aware

Net Income is used.

Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.


GRI Bio Return-on-Tangible-Equity Related Terms


GRI Bio Return-on-Tangible-Equity Historical Data

* Premium members only.

The historical data trend for GRI Bio's Return-on-Tangible-Equity can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

GRI Bio Return-on-Tangible-Equity Chart

GRI Bio Annual Data
Trend Dec21 Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Equity
0.00 0.00 0.00 -382.52 -238.17

GRI Bio Quarterly Data
Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Return-on-Tangible-Equity Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -465.30 -511.07 -505.59 -265.87 -96.56

GRI vs ISCO, VRAX, SLXN: Return-on-Tangible-Equity Comparison

For the Biotechnology subindustry, GRI Bio's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


GRI Bio Return-on-Tangible-Equity vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, GRI Bio's Return-on-Tangible-Equity distribution charts can be found below:

* The bar in red indicates where GRI Bio's Return-on-Tangible-Equity falls into.


GRI
33GF Score
GRI Bio Inc GRI
Return-on-Tangible-Equity is just one metric. See GF Score™, valuation, warning signs, and more.
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GRI Bio Return-on-Tangible-Equity Calculation

GRI Bio's annualized Return-on-Tangible-Equity for the fiscal year that ended in Dec. 2025 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets )/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-11.956/( (4.032+6.008 )/ 2 )
=-11.956/5.02
=-238.17 %

GRI Bio's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=-7.992/( (6.008+10.545)/ 2 )
=-7.992/8.2765
=-96.56 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. Return-on-Tangible-Equity is displayed in the 10-year financial page.

What does a Return-on-Tangible-Equity of -96.56% mean?
GRI Bio (GRI) has a Return-on-Tangible-Equity of -96.56% as of Mar. 2026. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on GRI Bio and its competitors. According to the industry distribution chart, GRI Bio ranks #1060 out of 1198 companies in the Biotechnology industry, placing it in the top 88.5%.
Is GRI Bio's Return-on-Tangible-Equity too high?
GRI Bio's current Return-on-Tangible-Equity is -96.56%. Based on the distribution chart, GRI Bio ranks #1060 out of 1198 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, GRI Bio has a GF Score™ of 33/100, reflecting its overall financial health beyond just this single metric.
How does GRI Bio's Return-on-Tangible-Equity compare to ISCO and VRAX?
According to the Biotechnology industry distribution chart, GRI Bio ranks #1060 out of 1198 companies for Return-on-Tangible-Equity. This places GRI Bio in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on GRI Bio and its competitors. GRI Bio's current Return-on-Tangible-Equity is -96.56%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is GRI Bio stock overvalued right now?
GRI Bio (GRI) has a current Return-on-Tangible-Equity of -96.56%. The current Return-on-Tangible-Equity is -96.56%. GRI Bio's overall GF Score™ is 33/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For GRI Bio (GRI), the current Return-on-Tangible-Equity is -96.56% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

GRI Bio Business Description

Address 2223 Avenida De La Playa, Suite 208, La Jolla, CA, USA, 92037
GRI Bio Inc is a clinical-stage biotech company focused on discovering, developing, and commercializing therapies targeting serious diseases associated with dysregulated immune responses that to inflammatory, fibrotic, and autoimmune disorders. GRI Bio's program, GRI-0621, is a small molecule RAR-beta and gamma dual agonist that inhibits the activity of human NKT I cells, returning the immune system to homeostasis. It is also an oral formulation of tazarotene, a synthetic RAR-beta and gamma selective agonist for the topical treatment of psoriasis and acne. The company's other product candidate GRI-0803 is a novel oral agonist of type 2 Natural Killer T (type 2 NKT) cells which can be a potential treatment for autoimmune disorders.
33GF Score

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Return-on-Tangible-Equity is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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