Lepu Biopharma Co (HKSE:02157) Return-on-Tangible-Equity: 88.69% (As of Dec. 2025)

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HKSE:02157 Lepu Biopharma Co Ltd HKSE:02157
44 GF Score
Price HK$4.82
GF Value HK$15.69
Valuation Possible Value Trap
! 6 Warning Signs
View Full Analysis

What is Lepu Biopharma Co Return-on-Tangible-Equity?

Lepu Biopharma Co HKSE:02157 +3.55% 44 Return-on-Tangible-Equity is 88.69% as of Dec. 2025. GuruFocus rates HKSE:02157 with a GF Score™ of 44/100 and a GF Value™ of HK$15.69 (Possible Value Trap). The stock has 6 warning signs investors should review. Among 1,197 Biotechnology companies, Lepu Biopharma Co ranks better than 96.57% on this metric.

Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. Lepu Biopharma Co's annualized net income for the quarter that ended in Dec. 2025 was HK$485 Mil. Lepu Biopharma Co's average shareholder tangible equity for the quarter that ended in Dec. 2025 was HK$547 Mil. Therefore, Lepu Biopharma Co's annualized Return-on-Tangible-Equity for the quarter that ended in Dec. 2025 was 88.69%.

The historical rank and industry rank for Lepu Biopharma Co's Return-on-Tangible-Equity or its related term are showing as below:

HKSE:02157' s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: -222.85   Med: -150.23   Max: 67.5
Current: 67.5

During the past 7 years, Lepu Biopharma Co's highest Return-on-Tangible-Equity was 67.50%. The lowest was -222.85%. And the median was -150.23%.

HKSE:02157's Return-on-Tangible-Equity is ranked better than
96.57% of 1197 companies
in the Biotechnology industry
Industry Median: -43.16 vs HKSE:02157: 67.50

Lepu Biopharma Co  (HKSE:02157) Return-on-Tangible-Equity Explanation

Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.


Be Aware

Net Income is used.

Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.


Lepu Biopharma Co Return-on-Tangible-Equity Related Terms


Lepu Biopharma Co Return-on-Tangible-Equity Historical Data

* Premium members only.

The historical data trend for Lepu Biopharma Co's Return-on-Tangible-Equity can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Lepu Biopharma Co Return-on-Tangible-Equity Chart

Lepu Biopharma Co Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Equity
Get a 7-Day Free Trial -187.27 -222.85 -6.18 -150.23 53.98

Lepu Biopharma Co Semi-Annual Data
Dec19 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Return-on-Tangible-Equity Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only 82.09 -101.86 -155.18 45.83 88.69

HKSE:02157 vs VRTX, REGN, RVMD: Return-on-Tangible-Equity Comparison

For the Biotechnology subindustry, Lepu Biopharma Co's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Lepu Biopharma Co Return-on-Tangible-Equity vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Lepu Biopharma Co's Return-on-Tangible-Equity distribution charts can be found below:

* The bar in red indicates where Lepu Biopharma Co's Return-on-Tangible-Equity falls into.


HKSE:02157
44GF Score
Lepu Biopharma Co Ltd HKSE:02157
Return-on-Tangible-Equity is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Lepu Biopharma Co Return-on-Tangible-Equity Calculation

Lepu Biopharma Co's annualized Return-on-Tangible-Equity for the fiscal year that ended in Dec. 2025 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets )/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=288.735/( (186.894+882.842 )/ 2 )
=288.735/534.868
=53.98 %

Lepu Biopharma Co's annualized Return-on-Tangible-Equity for the quarter that ended in Dec. 2025 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(Q: Dec. 2025 )  (Q: Jun. 2025 )(Q: Dec. 2025 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets)/ count )
(Q: Dec. 2025 )  (Q: Jun. 2025 )(Q: Dec. 2025 )
=485.238/( (211.387+882.842)/ 2 )
=485.238/547.1145
=88.69 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is two times the semi-annual (Dec. 2025) net income data. Return-on-Tangible-Equity is displayed in the 10-year financial page.

What does a Return-on-Tangible-Equity of 88.69% mean?
Lepu Biopharma Co (HKSE:02157) has a Return-on-Tangible-Equity of 88.69% as of Dec. 2025. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Lepu Biopharma Co and its competitors. According to the industry distribution chart, Lepu Biopharma Co ranks #41 out of 1197 companies in the Biotechnology industry, placing it in the top 3.4%.
Is Lepu Biopharma Co's Return-on-Tangible-Equity too high?
Lepu Biopharma Co's current Return-on-Tangible-Equity is 88.69%. Based on the distribution chart, Lepu Biopharma Co ranks #41 out of 1197 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Lepu Biopharma Co has a GF Score™ of 44/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Lepu Biopharma Co's Return-on-Tangible-Equity compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Lepu Biopharma Co ranks #41 out of 1197 companies for Return-on-Tangible-Equity. This places Lepu Biopharma Co in the top 3% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Lepu Biopharma Co and its competitors. Lepu Biopharma Co's current Return-on-Tangible-Equity is 88.69%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Lepu Biopharma Co stock overvalued right now?
Based on GuruFocus' analysis, Lepu Biopharma Co (HKSE:02157) is currently considered Possible Value Trap. The stock's GF Value™ is HK$15.69, compared to a current price of HK$4.82 — trading 69.3% below its estimated fair value. The current Return-on-Tangible-Equity is 88.69%. Lepu Biopharma Co's overall GF Score™ is 44/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For Lepu Biopharma Co (HKSE:02157), the current Return-on-Tangible-Equity is 88.69% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Lepu Biopharma Co (HKSE:02157) Overvalued in 2026?

Based on GuruFocus' analysis, Lepu Biopharma Co stock appears to be undervalued. The current stock price of HK$4.82 is trading 69.3% below its estimated GF Value™ of HK$15.69. GuruFocus considers Lepu Biopharma Co to be Possible Value Trap.

Key valuation signals for HKSE:02157:

  • Return-on-Tangible-Equity: 88.69%
  • GF Value™: HK$15.69 vs. price of HK$4.82 (69.3% below fair value)
  • GF Score™: 44/100 with 6 warning signs

No single metric tells the full story. See the HKSE:02157 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Lepu Biopharma Co Business Description

Address Lianheng Road, Block 4, No. 651, Minhang District, Shanghai, CHN, 201112
Lepu Biopharma Co Ltd is focused on discovering, developing, and commercializing drug candidates in anti-tumor targeted therapy and oncology immunotherapy. Its commercial products include Puyouheng (Pucotenlimab Injection) and Meiyouheng (Becotatug Vedotin Injection). In addition, two other products, CMG901 and MRG007, have also been licensed out through its business development activities. Additionally, the company has several clinical-stage drug candidates and clinical-stage combination therapies of candidates, which are being developed as targeted therapeutics and immunotherapeutics. The various drug candidates in its pipeline include MRG003, MRG002, MRG004A, CG0070, MRG001, and MRG006A, among others. Geographically, the company generates maximum revenue from the Chinese mainland.
44GF Score

Get the complete analysis for HKSE:02157

Return-on-Tangible-Equity is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

HK$4.82
Price
HK$15.69
GF Value