Seer (SEER) Return-on-Tangible-Equity: -26.90% (As of Mar. 2026)


SEER Seer Inc SEER
53 GF Score
Price $1.62
GF Value $2.20
Valuation Modestly Undervalued
! 3 Warning Signs
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What is Seer Return-on-Tangible-Equity?

Seer SEER -0.61% 53 Return-on-Tangible-Equity is -26.90% as of Mar. 2026. GuruFocus rates SEER with a GF Score™ of 53/100 and a GF Value™ of $2.20 (Modestly Undervalued). The stock has 3 warning signs investors should review. Among 1,196 Biotechnology companies, Seer ranks better than 60.54% on this metric.

Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. Seer's annualized net income for the quarter that ended in Mar. 2026 was $-67.35 Mil. Seer's average shareholder tangible equity for the quarter that ended in Mar. 2026 was $250.39 Mil. Therefore, Seer's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 was -26.90%.

The historical rank and industry rank for Seer's Return-on-Tangible-Equity or its related term are showing as below:

SEER' s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: -27.26   Med: -20.75   Max: -12.62
Current: -25.69

During the past 8 years, Seer's highest Return-on-Tangible-Equity was -12.62%. The lowest was -27.26%. And the median was -20.75%.

SEER's Return-on-Tangible-Equity is ranked better than
60.54% of 1196 companies
in the Biotechnology industry
Industry Median: -42.305 vs SEER: -25.69

Seer  (NAS:SEER) Return-on-Tangible-Equity Explanation

Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.


Be Aware

Net Income is used.

Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.


Seer Return-on-Tangible-Equity Related Terms


Seer Return-on-Tangible-Equity Historical Data

* Premium members only.

The historical data trend for Seer's Return-on-Tangible-Equity can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Seer Return-on-Tangible-Equity Chart

Seer Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Equity
Get a 7-Day Free Trial -15.23 -19.57 -20.45 -23.91 -25.08

Seer Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Return-on-Tangible-Equity Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -24.99 -25.93 -26.04 -24.09 -26.90

SEER vs CSBR, RLYB, FBIO: Return-on-Tangible-Equity Comparison

For the Biotechnology subindustry, Seer's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Seer Return-on-Tangible-Equity vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Seer's Return-on-Tangible-Equity distribution charts can be found below:

* The bar in red indicates where Seer's Return-on-Tangible-Equity falls into.


SEER
53GF Score
Seer Inc SEER
Return-on-Tangible-Equity is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Seer Return-on-Tangible-Equity Calculation

Seer's annualized Return-on-Tangible-Equity for the fiscal year that ended in Dec. 2025 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets )/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-73.6/( (327.569+259.307 )/ 2 )
=-73.6/293.438
=-25.08 %

Seer's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=-67.348/( (259.307+241.479)/ 2 )
=-67.348/250.393
=-26.90 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. Return-on-Tangible-Equity is displayed in the 10-year financial page.

What does a Return-on-Tangible-Equity of -26.90% mean?
Seer (SEER) has a Return-on-Tangible-Equity of -26.90% as of Mar. 2026. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Seer and its competitors. According to the industry distribution chart, Seer ranks #472 out of 1196 companies in the Biotechnology industry, placing it in the top 39.5%.
Is Seer's Return-on-Tangible-Equity too high?
Seer's current Return-on-Tangible-Equity is -26.90%. Based on the distribution chart, Seer ranks #472 out of 1196 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Seer has a GF Score™ of 53/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Seer's Return-on-Tangible-Equity compare to CSBR and RLYB?
According to the Biotechnology industry distribution chart, Seer ranks #472 out of 1196 companies for Return-on-Tangible-Equity. This puts Seer in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Seer and its competitors. Seer's current Return-on-Tangible-Equity is -26.90%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Seer stock overvalued right now?
Based on GuruFocus' analysis, Seer (SEER) is currently considered Modestly Undervalued. The stock's GF Value™ is $2.20, compared to a current price of $1.62 — trading 26.4% below its estimated fair value. The current Return-on-Tangible-Equity is -26.90%. Seer's overall GF Score™ is 53/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For Seer (SEER), the current Return-on-Tangible-Equity is -26.90% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Seer (SEER) Overvalued in 2026?

Based on GuruFocus' analysis, Seer stock appears to be undervalued. The current stock price of $1.62 is trading 26.4% below its estimated GF Value™ of $2.20. GuruFocus considers Seer to be Modestly Undervalued.

Key valuation signals for SEER:

  • Return-on-Tangible-Equity: -26.90%
  • GF Value™: $2.20 vs. price of $1.62 (26.4% below fair value)
  • GF Score™: 53/100 with 3 warning signs

No single metric tells the full story. See the SEER stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Seer Business Description

Address 3800 Bridge Parkway, Suite 102, Redwood City, CA, USA, 94065
Seer Inc is a life sciences company, develops and commercializes products to decode the biology of the proteome. The company offers Proteograph Product Suite, an integrated solution that includes proprietary engineered nanoparticles, consumables, automation instrumentation, and data analysis software to perform proteomic analysis to provide a solution that can be incorporated by nearly any lab for research use only. It markets and sells its products for research use only, which cover academic institutions, life sciences, and research laboratories, as well as biopharmaceutical and biotechnology companies for non-diagnostic and non-clinical purposes. The company operates in China, Australia, Eastern Europe, Israel, Japan and South Africa.
53GF Score

Get the complete analysis for SEER

Return-on-Tangible-Equity is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.62
Price
$2.20
GF Value