ENSCW (Ensysce Biosciences) ROA %: -295.72% (As of Mar. 2026)


ENSCW Ensysce Biosciences Inc ENSCW
23 GF Score
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What is Ensysce Biosciences ROA %?

Ensysce Biosciences ENSCW 23 ROA % is -295.72% as of Mar. 2026. GuruFocus rates ENSCW with a GF Score™ of 23/100. The stock has 2 warning signs investors should review. Among 1,423 Biotechnology companies, Ensysce Biosciences ranks worse than 95.64% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Ensysce Biosciences's annualized Net Income for the quarter that ended in Mar. 2026 was $-14.22 Mil. Ensysce Biosciences's average Total Assets over the quarter that ended in Mar. 2026 was $4.81 Mil. Therefore, Ensysce Biosciences's annualized ROA % for the quarter that ended in Mar. 2026 was -295.72%.

The historical rank and industry rank for Ensysce Biosciences's ROA % or its related term are showing as below:

ENSCW' s ROA % Range Over the Past 10 Years
Min: -346.88   Med: -204.56   Max: 16.19
Current: -256.38

During the past 6 years, Ensysce Biosciences's highest ROA % was 16.19%. The lowest was -346.88%. And the median was -204.56%.

ENSCW's ROA % is ranked worse than
95.64% of 1423 companies
in the Biotechnology industry
Industry Median: -32.9 vs ENSCW: -256.38

Ensysce Biosciences  (OTCPK:ENSCW) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Mar. 2026 )
=Net Income/Total Assets
=-14.224/4.81
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-14.224 / 0)*(0 / 4.81)
=Net Margin %*Asset Turnover
=N/A %*0
=-295.72 %

Note: The Net Income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Ensysce Biosciences ROA % Related Terms


Ensysce Biosciences ROA % Historical Data

* Premium members only.

The historical data trend for Ensysce Biosciences's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ensysce Biosciences ROA % Chart

Ensysce Biosciences Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
Get a 7-Day Free Trial -346.88 -216.77 -247.02 -192.34 -155.97

Ensysce Biosciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -152.49 -136.11 -340.82 -208.30 -295.72

ENSCW vs PPCB, ACUT, LSBCF: ROA % Comparison

For the Biotechnology subindustry, Ensysce Biosciences's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ensysce Biosciences ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Ensysce Biosciences's ROA % distribution charts can be found below:

* The bar in red indicates where Ensysce Biosciences's ROA % falls into.


ENSCW
23GF Score
Ensysce Biosciences Inc ENSCW
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
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Ensysce Biosciences ROA % Calculation

Ensysce Biosciences's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=-10.176/( (5.597+7.452)/ 2 )
=-10.176/6.5245
=-155.97 %

Ensysce Biosciences's annualized ROA % for the quarter that ended in Mar. 2026 is calculated as:

ROA %=Net Income (Q: Mar. 2026 )/( (Total Assets (Q: Dec. 2025 )+Total Assets (Q: Mar. 2026 ))/ count )
=-14.224/( (7.452+2.168)/ 2 )
=-14.224/4.81
=-295.72 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Mar. 2026) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -295.72% mean?
Ensysce Biosciences (ENSCW) has a ROA % of -295.72% as of Mar. 2026. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Ensysce Biosciences and its competitors. According to the industry distribution chart, Ensysce Biosciences ranks #1361 out of 1423 companies in the Biotechnology industry, placing it in the top 95.6%.
Is Ensysce Biosciences' ROA % too high?
Ensysce Biosciences' current ROA % is -295.72%. Based on the distribution chart, Ensysce Biosciences ranks #1361 out of 1423 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Ensysce Biosciences has a GF Score™ of 23/100, reflecting its overall financial health beyond just this single metric.
How does Ensysce Biosciences' ROA % compare to PPCB and ACUT?
According to the Biotechnology industry distribution chart, Ensysce Biosciences ranks #1361 out of 1423 companies for ROA %. This places Ensysce Biosciences in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Ensysce Biosciences and its competitors. Ensysce Biosciences's current ROA % is -295.72%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ensysce Biosciences stock overvalued right now?
Ensysce Biosciences (ENSCW) has a current ROA % of -295.72%. The current ROA % is -295.72%. Ensysce Biosciences' overall GF Score™ is 23/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Ensysce Biosciences (ENSCW), the current ROA % is -295.72% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Ensysce Biosciences Business Description

Other Exchanges ENSC:USA
Address 7946 Ivanhoe Avenue, Suite 201, La Jolla, CA, USA, 92037
Ensysce Biosciences Inc is a clinical-stage biotech company using its proprietary technology platforms to develop safer prescription drugs. The company is developing a new class of powerful, opioids that prevent both drug abuse and overdoses. Its products are anticipated to provide safer options to treat severe pain and assist in preventing deaths caused by opioid abuse, reducing human and economic costs. The company's current development pipeline includes two new drug platforms: an abuse-resistant opioid prodrug technology, theTrypsin Activated Abuse Protection, or the TAAP platform, and an over-dose protection opioid prodrug technology, the Multi-Pill Abuse Resistant, or the MPAR platform. The Company currently operates in one business segment, which is pharmaceuticals.
23GF Score

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