ACTU (Actuate Therapeutics) ROC %: -2,020.72% (As of Mar. 2026)


ACTU Actuate Therapeutics Inc ACTU
14 GF Score
Price $1.82
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What is Actuate Therapeutics ROC %?

Actuate Therapeutics ACTU -14.29% 14 ROC % is -2,020.72% as of Mar. 2026. GuruFocus rates ACTU with a GF Score™ of 14/100.

ROC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROIC %. Actuate Therapeutics's annualized return on capital (ROC %) for the quarter that ended in Mar. 2026 was -2,020.72%.

As of today (2026-06-27), Actuate Therapeutics's WACC % is 10.38%. Actuate Therapeutics's ROC % is -1675.49% (calculated using TTM income statement data). Actuate Therapeutics earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Actuate Therapeutics  (NAS:ACTU) ROC % Explanation

ROC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROIC %. The reason book values of debt and equity are used is because the book values are the capital the company received when issuing the debt or receiving the equity investments.

There are four key components to this definition. The first is the use of operating income or EBIT rather than net income in the numerator. The second is the tax adjustment to this operating income or EBIT, computed as a hypothetical tax based on an effective or marginal tax rate. The third is the use of book values for invested capital, rather than market values. The final is the timing difference; the capital invested is from the end of the prior year whereas the operating income or EBIT is the current year's number.

Why is ROC % important?

Because it costs money to raise capital. A firm that generates higher returns on investment than it costs the company to raise the capital needed for that investment is earning excess returns. A firm that expects to continue generating positive excess returns on new investments in the future will see its value increase as growth increases, whereas a firm that earns returns that do not match up to its cost of capital will destroy value as it grows.

As of today, Actuate Therapeutics's WACC % is 10.38%. Actuate Therapeutics's ROC % is -1675.49% (calculated using TTM income statement data). Actuate Therapeutics earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Be Aware

Like ROE % and ROA %, ROC % is calculated with only 12 months of data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.


Actuate Therapeutics ROC % Related Terms


Actuate Therapeutics ROC % Historical Data

* Premium members only.

The historical data trend for Actuate Therapeutics's ROC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Actuate Therapeutics ROC % Chart

Actuate Therapeutics Annual Data
Trend Dec22 Dec23 Dec24 Dec25
ROC %
-15,308.33 -12,182.44 -3,940.64 -2,272.22

Actuate Therapeutics Quarterly Data
Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -2,061.03 -1,520.76 -1,571.85 -1,787.61 -2,020.72
ACTU
14GF Score
Actuate Therapeutics Inc ACTU
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Actuate Therapeutics ROC % Calculation

Actuate Therapeutics's annualized Return on Capital (ROC %) for the fiscal year that ended in Dec. 2025 is calculated as:

ROC % (A: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (A: Dec. 2024 ) + Invested Capital (A: Dec. 2025 ))/ count )
=-22.495 * ( 1 - 0% )/( (0.999 + 0.981)/ 2 )
=-22.495/0.99
=-2,272.22 %

where

Actuate Therapeutics's annualized Return on Capital (ROC %) for the quarter that ended in Mar. 2026 is calculated as:

ROC % (Q: Mar. 2026 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Dec. 2025 ) + Invested Capital (Q: Mar. 2026 ))/ count )
=-22.824 * ( 1 - 0% )/( (0.981 + 1.278)/ 2 )
=-22.824/1.1295
=-2,020.72 %

where

Note: The Operating Income data used here is four times the quarterly (Mar. 2026) data. The tax rate is limited to between 0% and 100%.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about ROC % →
What does a ROC % of -2,020.72% mean?
Actuate Therapeutics (ACTU) has a ROC % of -2,020.72% as of Mar. 2026. Return on capital is the ratio of current-period net income to average two-period capital. View historical data on Actuate Therapeutics and its competitors.
Is Actuate Therapeutics' ROC % too high?
Actuate Therapeutics' current ROC % is -2,020.72%. Overall, Actuate Therapeutics has a GF Score™ of 14/100, reflecting its overall financial health beyond just this single metric.
How does Actuate Therapeutics' ROC % compare to AURX and ESLA?
Actuate Therapeutics' ROC % of -2,020.72% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROC % for a Biotechnology company?
A good ROC % depends on the Biotechnology industry context. However, ROC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROC % mean?
A high ROC % can signal that a stock is expensive relative to its fundamentals. Return on capital is the ratio of current-period net income to average two-period capital. View historical data on Actuate Therapeutics and its competitors. Actuate Therapeutics's current ROC % is -2,020.72%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Actuate Therapeutics stock overvalued right now?
Actuate Therapeutics (ACTU) has a current ROC % of -2,020.72%. The current ROC % is -2,020.72%. Actuate Therapeutics' overall GF Score™ is 14/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROC % calculated?
ROC % is calculated from a company's financial statements. For Actuate Therapeutics (ACTU), the current ROC % is -2,020.72% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Actuate Therapeutics Business Description

Address 1751 River Run, Suite 400, Fort Worth, TX, USA, 76107
Actuate Therapeutics Inc is a clinical stage biopharmaceutical company focused on developing therapies for the treatment of high impact, difficult to treat cancers through the inhibition of glycogen synthase kinase-3 (GSK-3). It is developing elraglusib (formerly 9-ING-41), a small molecule that is designed to enter cancer cells and block the function of the enzyme GSK-3B, a master regulator of complex biological signaling cascades, including those mediated by oncogenes, that lead to tumor cell survival, growth, migration, and invasion.
14GF Score

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ROC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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