ACTU (Actuate Therapeutics) 3-Year RORE % : -15.27% (As of Mar. 2026)


ACTU Actuate Therapeutics Inc ACTU
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Price $1.82
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What is Actuate Therapeutics 3-Year RORE %?

Actuate Therapeutics ACTU -14.29% 14 3-Year RORE % is -15.27 as of Mar. 2026. GuruFocus rates ACTU with a GF Score™ of 14/100. Among 1,295 Biotechnology companies, Actuate Therapeutics ranks worse than 53.82% on this metric.

Return on Retained Earnings (RORE) is an indicator of a company's growth potential, it shows how much a company earns by reinvesting its retained earnings, i.e. profits after dividend payments. Actuate Therapeutics's 3-Year RORE % for the quarter that ended in Mar. 2026 was -15.27%.

The industry rank for Actuate Therapeutics's 3-Year RORE % or its related term are showing as below:

ACTU's 3-Year RORE % is ranked worse than
53.82% of 1295 companies
in the Biotechnology industry
Industry Median: -11.53 vs ACTU: -15.27

Actuate Therapeutics  (NAS:ACTU) 3-Year RORE % Explanation

Return on Retained Earnings (RORE) is important to investors because it reveals a company's efficiency and growth potential. A higher RORE indicates a higher return. A high RORE indicates that the company should reinvest profits into the business. A lower RORE suggests that the company should distribute profits to shareholders by paying out dividends, since those dollars aren't generating much additional growth for the company.

There are a several different ways to arrive at the Return on Retained Earnings. The simplest way to calculate it is by using published information on Earnings per Share (EPS) and Dividend per Share (DPS) over a selected period. Here, 3-year period is chosen.

Be Aware

Please keep in mind that the RORE is relative to the nature of the business and its competitors. If another company in the same sector is producing a lower return on retained earnings, it doesn’t necessarily mean it’s a bad investment. It may just suggest the company is older and no longer in a high growth stage. At such a stage in the business cycle, it would be expected to see a lower RORE and higher dividend payout.


Actuate Therapeutics 3-Year RORE % Related Terms


Actuate Therapeutics 3-Year RORE % Historical Data

* Premium members only.

The historical data trend for Actuate Therapeutics's 3-Year RORE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Actuate Therapeutics 3-Year RORE % Chart

Actuate Therapeutics Annual Data
Trend Dec22 Dec23 Dec24 Dec25
3-Year RORE %
0.00 0.00 0.00 -10.78

Actuate Therapeutics Quarterly Data
Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
3-Year RORE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 2.33 -10.78 -15.27

ACTU vs AURX, ESLA, MGX: 3-Year RORE % Comparison

For the Biotechnology subindustry, Actuate Therapeutics's 3-Year RORE %, along with its competitors' market caps and 3-Year RORE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Actuate Therapeutics 3-Year RORE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Actuate Therapeutics's 3-Year RORE % distribution charts can be found below:

* The bar in red indicates where Actuate Therapeutics's 3-Year RORE % falls into.


ACTU
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Actuate Therapeutics Inc ACTU
3-Year RORE % is just one metric. See GF Score™, valuation, warning signs, and more.
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Actuate Therapeutics 3-Year RORE % Calculation

Actuate Therapeutics's 3-Year RORE % for the quarter that ended in Mar. 2026 is calculated as:

3-Year RORE %=( Most Recent EPS (Diluted)- First Period EPS (Diluted) )/( Cumulative EPS (Diluted) for 3-year -Cumulative Dividends per Share for 3-year )
=( -0.97--1.598 )/( -4.112-0 )
=0.628/-4.112
=-15.27 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of 3-Year RORE %, the most recent and first period EPS (Diluted) is the trailing twelve months (TTM) data ended in Mar. 2026 and 3-year before.

Frequently Asked Questions Learn more about 3-Year RORE % →
What does a 3-Year RORE % of -15.27 mean?
Actuate Therapeutics (ACTU) has a 3-Year RORE % of -15.27 as of Mar. 2026. 3-Year RORE % shows how much a company earns by reinvesting its retained earnings in 3-year. View historical data on Actuate Therapeutics and its competitors. According to the industry distribution chart, Actuate Therapeutics ranks #697 out of 1295 companies in the Biotechnology industry, placing it in the top 53.8%.
Is Actuate Therapeutics' 3-Year RORE % too high?
Actuate Therapeutics' current 3-Year RORE % is -15.27. Based on the distribution chart, Actuate Therapeutics ranks #697 out of 1295 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Actuate Therapeutics has a GF Score™ of 14/100, reflecting its overall financial health beyond just this single metric.
How does Actuate Therapeutics' 3-Year RORE % compare to AURX and ESLA?
According to the Biotechnology industry distribution chart, Actuate Therapeutics ranks #697 out of 1295 companies for 3-Year RORE %. This places Actuate Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year RORE % for a Biotechnology company?
A good 3-Year RORE % depends on the Biotechnology industry context. However, 3-Year RORE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year RORE % mean?
A high 3-Year RORE % can signal that a stock is expensive relative to its fundamentals. 3-Year RORE % shows how much a company earns by reinvesting its retained earnings in 3-year. View historical data on Actuate Therapeutics and its competitors. Actuate Therapeutics's current 3-Year RORE % is -15.27. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Actuate Therapeutics stock overvalued right now?
Actuate Therapeutics (ACTU) has a current 3-Year RORE % of -15.27. The current 3-Year RORE % is -15.27. Actuate Therapeutics' overall GF Score™ is 14/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year RORE % calculated?
3-Year RORE % is calculated from a company's financial statements. For Actuate Therapeutics (ACTU), the current 3-Year RORE % is -15.27 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Actuate Therapeutics Business Description

Address 1751 River Run, Suite 400, Fort Worth, TX, USA, 76107
Actuate Therapeutics Inc is a clinical stage biopharmaceutical company focused on developing therapies for the treatment of high impact, difficult to treat cancers through the inhibition of glycogen synthase kinase-3 (GSK-3). It is developing elraglusib (formerly 9-ING-41), a small molecule that is designed to enter cancer cells and block the function of the enzyme GSK-3B, a master regulator of complex biological signaling cascades, including those mediated by oncogenes, that lead to tumor cell survival, growth, migration, and invasion.
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