PRQR (ProQR Therapeutics NV) ROCE %: -75.13% (As of Mar. 2026)

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PRQR ProQR Therapeutics NV PRQR
48 GF Score
Price $1.72
GF Value $2.05
Valuation Modestly Undervalued
! 4 Warning Signs
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What is ProQR Therapeutics NV ROCE %?

ProQR Therapeutics NV PRQR -3.91% 48 ROCE % is -75.13% as of Mar. 2026. GuruFocus rates PRQR with a GF Score™ of 48/100 and a GF Value™ of $2.05 (Modestly Undervalued). The stock has 4 warning signs investors should review.

ROCE % measures how well a company generates profits from its capital. It is calculated as EBIT divided by Capital Employed, where Capital Employed is calculated as Total Assets minus Total Current Liabilities. ProQR Therapeutics NV's annualized ROCE % for the quarter that ended in Mar. 2026 was -75.13%.

ProQR Therapeutics NV  (NAS:PRQR) ROCE % Explanation

ROCE % can be especially useful when comparing the performance of capital-intensive companies. Unlike ROE %, which indicates the profitability of Shareholders Equity, ROCE % also considers long-term debt in Capital Employed. This can be helpful when analyzing companies with significant debt, as the result is neutralized by taking debt into consideration.

Generally speaking, a higher ROCE % indicates a stonger profitability for a company. Moreover, it is important to look at the ratio from a long term perspective. Investors tend to favor companies with stable and rising ROCE % trend over those with volatile ones.

ProQR Therapeutics NV ROCE % Related Terms

ProQR Therapeutics NV ROCE % Historical Data

* Premium members only.

The historical data trend for ProQR Therapeutics NV's ROCE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

ProQR Therapeutics NV ROCE % Chart

ProQR Therapeutics NV Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROCE %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -41.33 -34.25 -21.31 -22.68 -42.14

ProQR Therapeutics NV Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROCE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -35.61 -45.57 -46.57 -32.08 -75.13
PRQR
48GF Score
ProQR Therapeutics NV PRQR
ROCE % is just one metric. See GF Score™, valuation, warning signs, and more.
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ProQR Therapeutics NV ROCE % Calculation

ProQR Therapeutics NV's annualized ROCE % for the fiscal year that ended in Dec. 2025 is calculated as:

ROCE %=EBIT/( (Capital Employed+Capital Employed)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=EBIT/( ( (Total Assets - Total Current Liabilities)+(Total Assets - Total Current Liabilities) )/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-48.286/( ( (175.872 - 40.735) + (132.033 - 37.987) )/ 2 )
=-48.286/( (135.137+94.046)/ 2 )
=-48.286/114.5915
=-42.14 %

ProQR Therapeutics NV's ROCE % of for the quarter that ended in Mar. 2026 is calculated as:

ROCE %=EBIT (1)/( (Capital Employed+Capital Employed)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=EBIT/( ( (Total Assets - Total Current Liabilities)+(Total Assets - Total Current Liabilities) )/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=-63.116/( ( (132.033 - 37.987) + (114.49 - 40.529) )/ 2 )
=-63.116/( ( 94.046 + 73.961 )/ 2 )
=-63.116/84.0035
=-75.13 %

(1) Note: The EBIT data used here is four times the quarterly (Mar. 2026) EBIT data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about ROCE % →
What does a ROCE % of -75.13% mean?
ProQR Therapeutics NV (PRQR) has a ROCE % of -75.13% as of Mar. 2026.
Is ProQR Therapeutics NV's ROCE % too high?
ProQR Therapeutics NV's current ROCE % is -75.13%. Overall, ProQR Therapeutics NV has a GF Score™ of 48/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does ProQR Therapeutics NV's ROCE % compare to CRBP and NRXP?
ProQR Therapeutics NV's ROCE % of -75.13% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROCE % for a Biotechnology company?
A good ROCE % depends on the Biotechnology industry context. However, ROCE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROCE % mean?
A high ROCE % can signal that a stock is expensive relative to its fundamentals. ProQR Therapeutics NV's current ROCE % is -75.13%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is ProQR Therapeutics NV stock overvalued right now?
Based on GuruFocus' analysis, ProQR Therapeutics NV (PRQR) is currently considered Modestly Undervalued. The stock's GF Value™ is $2.05, compared to a current price of $1.72 — trading 16.1% below its estimated fair value. The current ROCE % is -75.13%. ProQR Therapeutics NV's overall GF Score™ is 48/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROCE % calculated?
ROCE % is calculated from a company's financial statements. For ProQR Therapeutics NV (PRQR), the current ROCE % is -75.13% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is ProQR Therapeutics NV (PRQR) Overvalued in 2026?

Based on GuruFocus' analysis, ProQR Therapeutics NV stock appears to be undervalued. The current stock price of $1.72 is trading 16.1% below its estimated GF Value™ of $2.05. GuruFocus considers ProQR Therapeutics NV to be Modestly Undervalued.

Key valuation signals for PRQR:

  • ROCE %: -75.13%
  • GF Value™: $2.05 vs. price of $1.72 (16.1% below fair value)
  • GF Score™: 48/100 with 4 warning signs

No single metric tells the full story. See the PRQR stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

ProQR Therapeutics NV Business Description

Other Exchanges 0PQ:Germany
Address Zernikedreef 9, Leiden, ZH, NLD, 2333 CK
ProQR Therapeutics NV is a biopharmaceutical company. It discovers and develops RNA therapeutics for patients with severe genetic rare diseases such as cystic fibrosis, Leber congenital amaurosis type 10, and dystrophic epidermolysis bullosa. The only reportable segment of the company is the discovery and development of different, RNA-based therapeutics. Geographically, the company operates in United States.
48GF Score

Get the complete analysis for PRQR

ROCE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.72
Price
$2.05
GF Value