CMMB (Chemomab Therapeutics) ROE %: -61.59% (As of Mar. 2026)


CMMB Chemomab Therapeutics Ltd CMMB
33 GF Score
Price $1.59
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What is Chemomab Therapeutics ROE %?

Chemomab Therapeutics CMMB 33 ROE % is -61.59% as of Mar. 2026. GuruFocus rates CMMB with a GF Score™ of 33/100. Among 1,255 Biotechnology companies, Chemomab Therapeutics ranks worse than 65.26% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. Chemomab Therapeutics's annualized net income for the quarter that ended in Mar. 2026 was $-7.09 Mil. Chemomab Therapeutics's average Total Stockholders Equity over the quarter that ended in Mar. 2026 was $11.51 Mil. Therefore, Chemomab Therapeutics's annualized ROE % for the quarter that ended in Mar. 2026 was -61.59%.

The historical rank and industry rank for Chemomab Therapeutics's ROE % or its related term are showing as below:

CMMB' s ROE % Range Over the Past 10 Years
Min: -91.34   Med: -63.07   Max: -34.53
Current: -68.49

During the past 6 years, Chemomab Therapeutics's highest ROE % was -34.53%. The lowest was -91.34%. And the median was -63.07%.

CMMB's ROE % is ranked worse than
65.26% of 1255 companies
in the Biotechnology industry
Industry Median: -38.18 vs CMMB: -68.49

Chemomab Therapeutics  (NAS:CMMB) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=-7.092/11.5145
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(-7.092 / 0)*(0 / 12.81)*(12.81 / 11.5145)
=Net Margin %*Asset Turnover*Equity Multiplier
=N/A %*0*1.1125
=ROA %*Equity Multiplier
=N/A %*1.1125
=-61.59 %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=-7.092/11.5145
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (-7.092 / -7.092) * (-7.092 / -7.4) * (-7.4 / 0) * (0 / 12.81) * (12.81 / 11.5145)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 1 * 0.9584 * N/A % * 0 * 1.1125
=-61.59 %

Note: The net income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


Chemomab Therapeutics ROE % Related Terms


Chemomab Therapeutics ROE % Historical Data

* Premium members only.

The historical data trend for Chemomab Therapeutics's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Chemomab Therapeutics ROE % Chart

Chemomab Therapeutics Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE %
Get a 7-Day Free Trial -34.53 -56.60 -91.02 -91.34 -69.54

Chemomab Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -111.09 -81.90 -66.58 -63.59 -61.59

CMMB vs HCWB, MTVA, INTI: ROE % Comparison

For the Biotechnology subindustry, Chemomab Therapeutics's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Chemomab Therapeutics ROE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Chemomab Therapeutics's ROE % distribution charts can be found below:

* The bar in red indicates where Chemomab Therapeutics's ROE % falls into.


CMMB
33GF Score
Chemomab Therapeutics Ltd CMMB
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
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Chemomab Therapeutics ROE % Calculation

Chemomab Therapeutics's annualized ROE % for the fiscal year that ended in Dec. 2025 is calculated as

ROE %=Net Income (A: Dec. 2025 )/( (Total Stockholders Equity (A: Dec. 2024 )+Total Stockholders Equity (A: Dec. 2025 ))/ count )
=-8.995/( (13.537+12.334)/ 2 )
=-8.995/12.9355
=-69.54 %

Chemomab Therapeutics's annualized ROE % for the quarter that ended in Mar. 2026 is calculated as

ROE %=Net Income (Q: Mar. 2026 )/( (Total Stockholders Equity (Q: Dec. 2025 )+Total Stockholders Equity (Q: Mar. 2026 ))/ count )
=-7.092/( (12.334+10.695)/ 2 )
=-7.092/11.5145
=-61.59 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. ROE % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of -61.59% mean?
Chemomab Therapeutics (CMMB) has a ROE % of -61.59% as of Mar. 2026. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Chemomab Therapeutics and its competitors. According to the industry distribution chart, Chemomab Therapeutics ranks #819 out of 1255 companies in the Biotechnology industry, placing it in the top 65.3%.
Is Chemomab Therapeutics' ROE % too high?
Chemomab Therapeutics' current ROE % is -61.59%. Based on the distribution chart, Chemomab Therapeutics ranks #819 out of 1255 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Chemomab Therapeutics has a GF Score™ of 33/100, reflecting its overall financial health beyond just this single metric.
How does Chemomab Therapeutics' ROE % compare to HCWB and MTVA?
According to the Biotechnology industry distribution chart, Chemomab Therapeutics ranks #819 out of 1255 companies for ROE %. This places Chemomab Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Biotechnology company?
A good ROE % depends on the Biotechnology industry context. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Chemomab Therapeutics and its competitors. Chemomab Therapeutics's current ROE % is -61.59%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Chemomab Therapeutics stock overvalued right now?
Chemomab Therapeutics (CMMB) has a current ROE % of -61.59%. The current ROE % is -61.59%. Chemomab Therapeutics' overall GF Score™ is 33/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For Chemomab Therapeutics (CMMB), the current ROE % is -61.59% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Chemomab Therapeutics Business Description

Address 10 Habarzel Street, 10th Floor, Building C, Tel Aviv, ISR, 6158101
Chemomab Therapeutics Ltd is a clinical-stage biotechnology company, focusing on the discovery and development of therapeutics for fibrosis-related diseases with large unmet needs. The company's candidate, CM-101, is a monoclonal antibody that targets CCL24 and was shown to interfere with the underlying biology of liver, skin, and lung fibrosis using a novel and differentiated mechanism of action. CM-101 has demonstrated the potential to treat multiple severe and life-threatening fibrotic and inflammatory diseases.
33GF Score

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ROE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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