COGT (Cogent Biosciences) 3-Year ROIIC % : -3,171.35% (As of Dec. 2025)


COGT Cogent Biosciences Inc COGT
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What is Cogent Biosciences 3-Year ROIIC %?

Cogent Biosciences COGT +0.55% 25 3-Year ROIIC % is -3,171.35 as of Dec. 2025. GuruFocus rates COGT with a GF Score™ of 25/100. The stock has 4 warning signs investors should review. Among 1,324 Biotechnology companies, Cogent Biosciences ranks worse than 98.11% on this metric.

3-Year Return on Invested Incremental Capital (3-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 3-year. Cogent Biosciences's 3-Year ROIIC % for the quarter that ended in Dec. 2025 was -3,171.35%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

The industry rank for Cogent Biosciences's 3-Year ROIIC % or its related term are showing as below:

COGT's 3-Year ROIIC % is ranked worse than
98.11% of 1324 companies
in the Biotechnology industry
Industry Median: -4.42 vs COGT: -3171.35

Cogent Biosciences  (NAS:COGT) 3-Year ROIIC % Explanation

Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.

High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

Be Aware

It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.


Cogent Biosciences 3-Year ROIIC % Related Terms


Cogent Biosciences 3-Year ROIIC % Historical Data

* Premium members only.

The historical data trend for Cogent Biosciences's 3-Year ROIIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Cogent Biosciences 3-Year ROIIC % Chart

Cogent Biosciences Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
3-Year ROIIC %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 559.35 -382.05 -442.84 -737.91 -3,171.35

Cogent Biosciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
3-Year ROIIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 -3,171.35 0.00

COGT vs SRRK, CGON, LGND: 3-Year ROIIC % Comparison

For the Biotechnology subindustry, Cogent Biosciences's 3-Year ROIIC %, along with its competitors' market caps and 3-Year ROIIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Cogent Biosciences 3-Year ROIIC % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Cogent Biosciences's 3-Year ROIIC % distribution charts can be found below:

* The bar in red indicates where Cogent Biosciences's 3-Year ROIIC % falls into.


COGT
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Cogent Biosciences Inc COGT
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Cogent Biosciences 3-Year ROIIC % Calculation

Cogent Biosciences's 3-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:

3-Year ROIIC %=3-Year Incremental Net Operating Profit After Taxes (NOPAT)**/3-Year Incremental Invested Capital**
=( -333.363 (Dec. 2025) - -147.839 (Dec. 2022) )/( 51.284 (Dec. 2025) - 45.434 (Dec. 2022) )
=-185.524/5.8499999999999
=-3,171.35%***

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** Annual data of NOPAT and Invested Capital was used to calculate 3-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.

Frequently Asked Questions Learn more about 3-Year ROIIC % →
What does a 3-Year ROIIC % of -3,171.35 mean?
Cogent Biosciences (COGT) has a 3-Year ROIIC % of -3,171.35 as of Dec. 2025. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Cogent Biosciences and its competitors. According to the industry distribution chart, Cogent Biosciences ranks #1299 out of 1324 companies in the Biotechnology industry, placing it in the top 98.1%.
Is Cogent Biosciences' 3-Year ROIIC % too high?
Cogent Biosciences' current 3-Year ROIIC % is -3,171.35. Based on the distribution chart, Cogent Biosciences ranks #1299 out of 1324 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Cogent Biosciences has a GF Score™ of 25/100, reflecting its overall financial health beyond just this single metric.
How does Cogent Biosciences' 3-Year ROIIC % compare to SRRK and CGON?
According to the Biotechnology industry distribution chart, Cogent Biosciences ranks #1299 out of 1324 companies for 3-Year ROIIC %. This places Cogent Biosciences in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year ROIIC % for a Biotechnology company?
A good 3-Year ROIIC % depends on the Biotechnology industry context. However, 3-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year ROIIC % mean?
A high 3-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Cogent Biosciences and its competitors. Cogent Biosciences's current 3-Year ROIIC % is -3,171.35. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Cogent Biosciences stock overvalued right now?
Cogent Biosciences (COGT) has a current 3-Year ROIIC % of -3,171.35. The current 3-Year ROIIC % is -3,171.35. Cogent Biosciences' overall GF Score™ is 25/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year ROIIC % calculated?
3-Year ROIIC % is calculated from a company's financial statements. For Cogent Biosciences (COGT), the current 3-Year ROIIC % is -3,171.35 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Cogent Biosciences Business Description

Address 275 Wyman Street, 3rd Floor, Waltham, MA, USA, 02451
Cogent Biosciences Inc a biotechnology company focused on developing precision therapies for genetically defined diseases. It designs rational precision therapies that treat the underlying cause of disease and improve the lives of patients. Its program CGT9486, is a selective tyrosine kinase inhibitor designed to potently inhibit the KIT D816V mutation as well as other mutations in KIT exon 17. In the vast majority of cases, KIT D816V is responsible for driving Systemic Mastocytosis (SM), a serious disease caused by the unchecked proliferation of mast cells. Exon 17 mutations are also found in patients with advanced gastrointestinal stromal tumors (GIST), a type of cancer with dependence on oncogenic KIT signaling.
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