Insider List

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Total 52

Insider Name
Andrew I Koven
Baker Bros. Advisors (gp) Llc
Baker Bros. Advisors Lp
Bakker Juliet Tammenoms
Bruce Kovner
C. Daniel Myers
Caxton Corp
Cdk Associates, L.l.c.
Charles Douglas Mcdermott
Cvf, Llc
Darius Kharabi
Eric Trachtenberg
Felix Baker
Gregory D Perry
Gregory Grunberg
Hadley Harbor Master Investors (cayman) L.p.
Hongming Chen
Howard B Rosen
Julian Baker
Justin Hanes
Longitude Capital Partners Ii, Llc
Longitude Venture Partners Ii, L.p.
Lux Capital Management, Llc
Lux Venture Associates Ii, Llc
Lux Venture Partners Ii, L.p.
Lux Ventures Ii Sidecar Lp
Lux Ventures Ii, L.p.
Marjan Farid
Mark S. Blumenkranz
Mark T Iwicki
Mary Reumuth
Michele Larussa
Orbimed Advisors Llc
Orbimed Capital Gp Vi Llc
Patrick G Enright
Paulina Hill
Peter Kolchinsky
Polaris Venture Management Co. V, L.l.c.
Polaris Venture Partners Entrepreneurs' Fund V, L.p.
Polaris Venture Partners Founders' Fund V, L.p.

Insider Name	Latest Transaction Date	Aggregate Performance						Aggregate Performance Relative to S&P 500						Companys
Insider Name	Latest Transaction Date	1M	3M	6M	1Y	2Y	3Y	1M	3M	6M	1Y	2Y	3Y	Companys
Insider Name	Latest Transaction Date	Aggregate Performance						Aggregate Performance Relative to S&P 500						Companys
Insider Name	Latest Transaction Date	1M	3M	6M	1Y	2Y	3Y	1M	3M	6M	1Y	2Y	3Y	Companys
Andrew I Koven		-	-	-	-	-	-	-	-	-	-	-	-	KALA ARLZQ MTVA
Baker Bros. Advisors (gp) Llc	2015-08-07	-	-	-	-	-	-	-	-	-	-	-	-	TCRX NGNE MDGL BCYC IGMS NTLA ... RYTM XOMA INCY BCRX ONC ACAD KOD KALA SERA CELC DBVT SYRE VTVT IMCR PRLD TRDA DNLI KNSA REPL HOOK KYMR
Baker Bros. Advisors Lp	2025-09-08	3.320	3.320	11.670	26.470	-9.270	-16.960	1.750	10.020	4.270	11.670	-21.510	-28.370	IGMS INCY KOD PRLD KNSA BCEL ... ONC ACAD SGEN ALXN ZYME NLTX ACGN HOOK PRNB NVTAQ BLCM MRTX RYTM BCRX NTLA XOMA XOMAO.PFD TLIS DBVT SYRE TRDA TCRX MDGL NGNE BCYC KALA SERA CELC VTVT IMCR DNLI REPL KYMR
Bakker Juliet Tammenoms	2024-10-15	-2.030	-2.030	10.260	9.130	15.490	5.560	-2.840	7.650	3.250	-5.100	6.050	-5.410	EAR AXNX MTEMQ INZY ETNB PCVX ... VERO SRRA TCDAQ APTX AIMT COLL KALA CORT ESPR RXST RPID TALS VERA LXEO CBLL TRML
Bruce Kovner		-	-	-	-	-	-	-	-	-	-	-	-	SBBP MTEMQ KALA CPXX MDGL
C. Daniel Myers	2020-08-20	-	-	-	-	-	-	-	-	-	-	-	-	ALIM KALA
Caxton Corp		-	-	-	-	-	-	-	-	-	-	-	-	SBBP MTEMQ KALA CPXX MDGL
Cdk Associates, L.l.c.	2020-09-18	11.520	11.520	3.470	-13.010	-16.340	-17.050	8.630	1.500	-3.940	-29.700	-28.610	-31.790	SBBP MTEMQ KALA CPXX
Charles Douglas Mcdermott		-	-	-	-	-	-	-	-	-	-	-	-	EQ KALA
Cvf, Llc	2024-02-06	-7.420	-7.420	-47.470	-70.610	-76.150	-54.560	-9.850	-15.120	-56.740	-88.230	-87.030	-63.340	KALA RNTX DARE GUTS
Darius Kharabi	2025-10-22	-	-	-	-	-	-	-	-	-	-	-	-	KALA
Eric Trachtenberg	2024-01-04	-	-	-	-	-	-	-	-	-	-	-	-	KALA ARLZQ
Felix Baker	2016-11-08	5.580	5.580	22.870	29.840	19.200	11.310	4.360	7.520	14.590	14.110	4.670	0.940	IGMS INCY KOD PRLD KNSA BCEL ... ONC ACAD SGEN ALXN ZYME NLTX ACGN HOOK PRNB NVTAQ BLCM MRTX RYTM BCRX NTLA XOMA OCRX HRTX XOMAO.PFD TLIS DBVT SYRE TRDA TCRX MDGL NGNE BCYC KALA SERA CELC VTVT IMCR DNLI REPL KYMR
Gregory D Perry	2013-09-10	-	-	-	-	-	-	-	-	-	-	-	-	MRUS KALA NVLNF AEGR OCAT SESN ... NVIVQ IMGN FNCH CARM
Gregory Grunberg	2020-07-10	18.310	18.310	7.170	-17.470	-33.900	-30.590	17.770	8.600	-3.450	-40.550	-49.260	-41.900	ETNB KALA
Hadley Harbor Master Investors (cayman) L.p.	2020-03-25	-	-	-	-	-	-	-	-	-	-	-	-	PTON PINS NTGN LASR ZUO ALNAQ ... FSCT RYTM KALA TTD JNCE CRSP VYGR CTMX ALPN IVTY
Hongming Chen	2021-10-27	-	-	-	-	-	-	-	-	-	-	-	-	KALA
Howard B Rosen	2019-05-30	7.120	7.120	-10.620	53.350	-4.650	-29.960	3.580	-9.530	-19.820	40.360	-23.800	-42.680	KALA TLPH
Julian Baker	2016-10-07	1.250	1.250	-1.670	38.110	-4.720	-4.650	-1.020	-1.590	-8.780	17.980	-22.120	-18.490	IGMS INCY KOD PRLD KNSA BCEL ... ONC ACAD SGEN ALXN ZYME NLTX ACGN HOOK PRNB NVTAQ BLCM MRTX RYTM BCRX NTLA XOMA OCRX HRTX INVA XOMAO.PFD TLIS DBVT SYRE TRDA TCRX MDGL NGNE BCYC KALA SERA CELC VTVT IMCR DNLI REPL KYMR
Justin Hanes		-	-	-	-	-	-	-	-	-	-	-	-	KALA
Longitude Capital Partners Ii, Llc	2021-07-19	-1.060	-1.060	-18.960	-14.660	-13.120	-18.310	-1.390	-7.200	-16.090	-24.870	-22.190	-31.190	PCVX VERO TCDAQ APTX KALA AIMT ... RPID
Longitude Venture Partners Ii, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	PCVX VERO TCDAQ APTX KALA AIMT ... RPID
Lux Capital Management, Llc	2016-10-13	0.290	0.290	24.780	72.570	0.220	-6.690	-1.210	12.070	15.570	52.850	-13.710	-18.390	KALA MRAM DARE GNCAQ SNCE GGNNQ
Lux Venture Associates Ii, Llc		-	-	-	-	-	-	-	-	-	-	-	-	KALA MRAM DARE GNCAQ GGNNQ
Lux Venture Partners Ii, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	KALA MRAM DARE GNCAQ GGNNQ
Lux Ventures Ii Sidecar Lp		-	-	-	-	-	-	-	-	-	-	-	-	KALA MRAM DARE GNCAQ GGNNQ
Lux Ventures Ii, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	KALA MRAM DARE GNCAQ GGNNQ
Marjan Farid		-	-	-	-	-	-	-	-	-	-	-	-	KALA
Mark S. Blumenkranz		-	-	-	-	-	-	-	-	-	-	-	-	ISEE ONEM ADVM LENSF KALA
Mark T Iwicki	2025-10-23	6.260	6.260	-19.260	-31.430	-7.580	7.250	11.380	-6.360	-14.850	-34.120	-14.640	-3.530	AIMT MRUS KALA AKRO PULM AVTE ... THRD QTTB IKT JBIO
Mary Reumuth	2025-10-23	-	-	-	-	-	-	-	-	-	-	-	-	KALA
Michele Larussa		-	-	-	-	-	-	-	-	-	-	-	-	KALA
Orbimed Advisors Llc	2025-10-08	4.190	4.190	1.110	-1.730	-8.760	-13.660	3.670	5.010	-3.840	-13.220	-19.930	-24.880	ARQT XTNT LOGC CALC PRLD PMVP ... ETNB INSP AFIB PAND FUSN RPTX SCPH ORIC ALEC KROS IMRA CTIC PASG SRRA TCDAQ TELA SWTX CRVS PRVL PRNB NXTC TPTX AVDR ALPN THOR SIBN GH ARVN STDY VRAYQ CNST CRNX ARPO ARMO ADAPY RYTM PIRS BOLD GKOS KALA SYBX LOXO XFOR ROKA SYRE NBRVF RPBIF RLYP RNAC NTLA OTIC DMTX SIENQ ICPT MRTX XLRN SUPN ANTH AMRN PCRX CCXI ATHXQ NXTM KURU ALBO ARYX PODD WHWK NPCE DBTX VRNA SBTX EWTX ACET CMPX THRX KNTE GLTO IRON JANX TERN IKNA THRD SPRY ELVN TSBX PVLA MBX TRAW QTTB AVBP UPB SION STTK IMA
Orbimed Capital Gp Vi Llc		-	-	-	-	-	-	-	-	-	-	-	-	LOGC CALC PRLD ETNB SCPH ORIC ... CTIC SWTX PRVL NXTC TPTX AVDR ALPN ARVN STDY CNST CRNX KALA SYBX NPCE VRNA SBTX EWTX ACET IRON IKNA SPRY TSBX CMPX IMA
Patrick G Enright	2025-10-09	11.720	11.720	26.510	46.560	49.510	13.300	9.720	1.950	21.940	35.810	38.670	2.120	EAR AIMT APTX MTEMQ JAZZ INZY ... ETNB PCVX SRRA VERO AXNX TCDAQ COLL KALA CORT ESPR SQNM RPID TALS VERA LXEO ZBIO BIOA TRML
Paulina Hill		-	-	-	-	-	-	-	-	-	-	-	-	STIM KALA
Peter Kolchinsky	2020-06-23	-10.530	-10.530	-9.150	165.390	-58.080	-	-11.420	9.750	-22.790	138.080	-68.180	-	PCVX CRDF PMVP DYN ETNB TGTX ... INBX WVE INZY ITOS PAND NKTX RACA RYTM AKUS VSTM FMTX RARX PHAT IMRA KALA SCPH THOR DRNA STSA EIGRQ ARVN EIDX KALV GTHX ACRS ACHN SGMO DSCI BSTC ARDMQ SQNM CRIS RXST ABOS VRDN DICE ITRM SLDB ORTX CLYM HOWL ICVX AVTE PNT VOR JANX RACB CTKB PEPG TYRA ANTX FULC SBTX ACRV SPRY ELVN MLYS BDTX SEPN CDTX FDMT BOLD JBIO LENZ ARTV BCAX SION
Polaris Venture Management Co. V, L.l.c.	2017-11-20	-14.430	-14.430	27.340	-28.100	-25.730	-43.850	-19.980	-5.060	17.740	-41.320	-36.850	-54.890	LYRA PHR CDLX PULM XFOR KALA ... RNAC TTOO GNCAQ ATYR OCUL TRVN DARE FATE BINDQ IVVD GGNNQ
Polaris Venture Partners Entrepreneurs' Fund V, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	LYRA ATYR OCUL DARE PHR TRVN ... FATE RNAC GNCAQ KALA TTOO XFOR PULM CDLX IVVD GGNNQ
Polaris Venture Partners Founders' Fund V, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	LYRA ATYR OCUL DARE PHR TRVN ... FATE RNAC GNCAQ KALA TTOO XFOR PULM CDLX IVVD GGNNQ

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Total 52

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