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          Insider List 
 Insider List
| Insider Name   | Latest Transaction Date   | Aggregate Performance   | Aggregate Performance Relative to S&P 500   | Companys   | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1M | 3M | 6M | 1Y | 2Y | 3Y | 1M | 3M | 6M | 1Y | 2Y | 3Y | |||
| Insider Name   | Latest Transaction Date   | Aggregate Performance   | Aggregate Performance Relative to S&P 500   | Companys   | ||||||||||
| 1M | 3M | 6M | 1Y | 2Y | 3Y | 1M | 3M | 6M | 1Y | 2Y | 3Y | |||
| - | - | - | - | - | - | - | - | - | - | - | - | APRE
      
        CRNX
      
        IDYA
      
        FIXX
      
        SCPH
      
        PEARQ 
      ...
      | ||
| 2017-11-21 | -15.710 | -15.710 | -3.140 | -68.070 | -41.320 | -13.890 | -19.000 | 4.560 | -8.300 | -70.030 | -50.600 | -24.920 | APRE
      
        CRNX
      
        IDYA
      
        FIXX
      
        SCPH
      
        PEARQ 
      ...
      | |
| 2019-10-07 | 15.320 | 15.320 | 12.330 | 10.290 | -11.880 | -24.620 | 11.340 | 18.590 | 10.820 | 0.070 | -29.380 | -36.950 | APRE
      
        CRNX
      
        IDYA
      
        FIXX
      
        SCPH
      
        PEARQ 
      ...
      | |
| 2010-04-23 | 7.570 | 7.570 | -15.260 | -27.840 | -23.570 | -3.310 | 11.780 | 6.280 | -22.000 | -44.120 | -36.910 | -14.930 | CBMG PSTX AKUS FMTX GRTX BCYC | |
| 2023-09-06 | - | - | - | - | - | - | - | - | - | - | - | - | FIXX QTTB | |
| - | - | - | - | - | - | - | - | - | - | - | - | FIXX SANA QTTB TECX | ||
| 2024-10-15 | -19.530 | -19.530 | -36.530 | -50.140 | -23.760 | 7.830 | -20.300 | -39.920 | -43.590 | -77.620 | -40.220 | -4.190 | FVAM APRE AKUS SCPH CABA ARVN | |
| Arch Venture Fund Viii Overage, L.p. | 2022-09-13 | -14.310 | -14.310 | -20.620 | -15.490 | -46.790 | 33.940 | -15.920 | 11.380 | -30.800 | -35.830 | -52.830 | 22.690 | CDAKQ MTCR FIXX SNNAQ TWST UNBX | 
| - | - | - | - | - | - | - | - | - | - | - | - | CDAKQ
      
        MTCR
      
        DNLI
      
        FIXX
      
        SNNAQ
      
        SRRK 
      ...
      | ||
| Arch Venture Partners Viii, L.p. | - | - | - | - | - | - | - | - | - | - | - | - | CDAKQ
      
        MTCR
      
        DNLI
      
        FIXX
      
        SNNAQ
      
        SRRK 
      ...
      | |
| Arch Venture Partners Viii, Llc | - | - | - | - | - | - | - | - | - | - | - | - | CDAKQ MTCR DNLI FIXX SNNAQ TWST | |
| 2015-04-09 | -9.760 | -9.760 | -40.630 | -29.020 | -40.580 | -50.580 | -11.100 | -10.780 | -41.980 | -33.770 | -47.390 | -58.620 | AKUS
      
        STOK
      
        FIXX
      
        BINDQ
      
        MLND
      
        TPST 
      ...
      | |
| - | - | - | - | - | - | - | - | - | - | - | - | ONCR FIXX NUVL QTTB | ||
| 2017-11-09 | -6.510 | -6.510 | -27.780 | -12.970 | 17.300 | 7.460 | -9.100 | -52.370 | -32.160 | -20.570 | 7.890 | -3.690 | CDAKQ MTCR PI BEAM VIR DNLI | |
| Deerfield Healthcare Innovations Fund, L.p. | - | - | - | - | - | - | - | - | - | - | - | - | ONCR CALC LRMR FIXX MIRM EDIT | |
| Deerfield Management Company, L.p. (series C) | 2021-07-30 | -2.400 | -2.400 | -4.100 | -2.800 | 1.590 | - | -5.440 | -6.780 | -4.930 | 3.230 | -0.520 | - | ONCR
      
        LRMR
      
        CALC
      
        AFIB
      
        ANNX
      
        DFHTU 
      ...
      
 | 
| - | - | - | - | - | - | - | - | - | - | - | - | ONCR CALC LRMR FIXX MIRM EDIT | ||
| - | - | - | - | - | - | - | - | - | - | - | - | ONCR CALC AFIB LRMR LUMO FIXX | ||
| - | - | - | - | - | - | - | - | - | - | - | - | ONCR
      
        CALC
      
        AFIB
      
        ANNX
      
        DFHTU
      
        NKTX 
      ...
      
 | ||
| - | - | - | - | - | - | - | - | - | - | - | - | ONCR CALC AFIB ANNX DFHTU NKTX | ||
| Deerfield Private Design Fund Iii, L.p. | - | - | - | - | - | - | - | - | - | - | - | - | ONCR CALC AFIB LRMR LUMO FIXX | |
| 2015-12-09 | -12.700 | -12.700 | -44.760 | -61.580 | 4.460 | -24.800 | -6.570 | -37.490 | -48.070 | -71.900 | -9.330 | -33.550 | CHRS VIR GH AMRSQ FIXX PTLA | |
| 2022-01-05 | - | - | - | - | - | - | - | - | - | - | - | - | FIXX QTTB | |
| 2025-07-31 | 1.610 | 1.610 | -8.780 | -9.270 | -14.340 | -22.330 | 0.920 | -2.270 | -13.430 | -20.460 | -24.460 | -29.580 | ONCR
      
        LRMR
      
        CALC
      
        AFIB
      
        ANNX
      
        DFHTU 
      ...
      
 | |
| 2025-10-02 | - | - | - | - | - | - | - | - | - | - | - | - | FIXX ALNY CRVO QTTB | |
| 2019-05-28 | -12.550 | -12.550 | -34.500 | -17.430 | 32.960 | -1.760 | -17.520 | -49.850 | -47.030 | -25.520 | 10.510 | -15.820 | APRE IDYA ARVN CRNX FIXX SCPH | |
| 2023-08-03 | - | - | - | - | - | - | - | - | - | - | - | - | FIXX NGNE QTTB | |
| 2024-04-02 | 21.490 | 21.490 | -12.270 | -19.030 | 22.890 | 32.790 | 19.420 | 1.970 | -19.580 | -29.460 | 17.180 | 19.640 | CDAKQ QTRX MTCR BEAM TWST VIR | |
| 2021-11-02 | -9.580 | -9.580 | -45.450 | -46.470 | -45.900 | -44.370 | -11.090 | -30.030 | -52.470 | -54.050 | -48.560 | -52.000 | FVAM APRE AKUS FIXX CABA ARVN | |
| 2025-08-01 | - | - | - | - | - | - | - | - | - | - | - | - | SLNO FIXX IMPLQ BOLT VRNA QTTB | |
| - | - | - | - | - | - | - | - | - | - | - | - | FIXX
      
        DMTX
      
        TCRT
      
        TRDA
      
        VIGL
      
        QTTB 
      ...
      | ||
| 2019-11-08 | - | - | - | - | - | - | - | - | - | - | - | - | FVAM FIXX BOLD FOLD VOR QTTB | |
| 2023-01-09 | - | - | - | - | - | - | - | - | - | - | - | - | FIXX QTTB | |
| Novartis Institutes For Biomedical Research, Inc. | 2018-04-23 | 12.010 | 12.010 | -39.800 | -56.440 | -27.810 | -16.130 | 10.070 | -16.510 | -43.540 | -69.360 | -36.470 | -30.060 | NTLA SURF FIXX QTTB | 
| 2024-03-25 | - | - | - | - | - | - | - | - | - | - | - | - | FIXX QTTB | |
| 2016-11-02 | 13.940 | 13.940 | 160.000 | 221.820 | 85.370 | 22.620 | 9.460 | 32.490 | 146.020 | 198.850 | 71.440 | 9.110 | FIXX IMGN PMN QTTB | |
| 2025-08-01 | -3.160 | -3.160 | 35.040 | 53.130 | 23.960 | 3.020 | -6.340 | -2.380 | 28.240 | 37.860 | 6.150 | -8.430 | CDAKQ MTCR UNBX KRTX DNLI VIR | |
| - | - | - | - | - | - | - | - | - | - | - | - | INZY IMRA FIXX TPST AVIR THRX | ||
| Rock Springs Capital Management Lp | 2021-10-26 | 22.210 | 22.210 | -59.060 | -79.130 | -62.500 | -55.310 | 22.200 | 0.290 | -52.720 | -70.120 | -63.590 | -63.980 | INZY IMRA FIXX ALPN DARE TPST | 
| Rock Springs Capital Master Fund Lp | 2021-10-12 | 22.400 | 22.400 | 12.150 | -26.180 | -45.030 | -38.170 | 14.390 | 56.150 | -5.910 | -46.770 | -53.910 | -49.750 | INZY IMRA FIXX TPST AVIR THRX | 
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