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Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
Charles River Laboratories InternationalCRL -0.14%70 Cyclically Adjusted PB Ratio is 4.29 as of Jul. 21, 2026, which is 31% below its 10-year median of 6.24. GuruFocus rates CRL with a GF Score™ of 70/100 and a GF Value™ of $194.04 (Modestly Overvalued). The stock has 8 warning signs investors should review. Among 136 Medical Diagnostics & Research companies, Charles River Laboratories International ranks worse than 76.47% on this metric.
CRL's Cyclically Adjusted PB Ratio is ranked worse than 76.47% of 136
companies
in the Medical Diagnostics & Research industry
Industry Median: 1.8
vs CRL: 4.29
The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.
Charles River Laboratories International's adjusted book value per share data for the three months ended in Mar. 2026 was $61.050. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $51.15 for the trailing ten years ended in Mar. 2026.
Shiller PE for Stocks: The True Measure of Stock Valuation
Charles River Laboratories International (NYSE:CRL) Cyclically Adjusted PB Ratio Explanation
Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.
If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.
Charles River Laboratories International Cyclically Adjusted PB Ratio Related Terms
Charles River Laboratories International Cyclically Adjusted PB Ratio Historical Data
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Charles River Laboratories International Cyclically Adjusted PB Ratio Chart
Charles River Laboratories International Annual Data
CRL vs RVTY, QGEN, ICLR: Cyclically Adjusted PB Ratio Comparison
For the Diagnostics & Research subindustry, Charles River Laboratories International's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Charles River Laboratories International Cyclically Adjusted PB Ratio vs Medical Diagnostics & Research Industry
For the Medical Diagnostics & Research industry and Healthcare sector, Charles River Laboratories International's Cyclically Adjusted PB Ratio distribution charts can be found below:
* The bar in red indicates where Charles River Laboratories International's Cyclically Adjusted PB Ratio falls into.
Charles River Laboratories International Cyclically Adjusted PB Ratio Calculation
Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.
The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.
What does a Cyclically Adjusted PB Ratio of 4.29 mean?
Charles River Laboratories International (CRL) has a Cyclically Adjusted PB Ratio of 4.29 as of Jul. 21, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Charles River Laboratories International and its competitors. This is 31% below median its historical median of 6.24. Over the past decade, Charles River Laboratories International's Cyclically Adjusted PB Ratio has ranged from 2.21 to 19.58. According to the industry distribution chart, Charles River Laboratories International ranks #104 out of 136 companies in the Medical Diagnostics & Research industry, placing it in the top 76.5%.
Is Charles River Laboratories International's Cyclically Adjusted PB Ratio too high?
Charles River Laboratories International's current Cyclically Adjusted PB Ratio of 4.29 is 31% below median its 10-year median of 6.24. Over the past 10 years, this metric has ranged from a low of 2.21 to a high of 19.58. The Medical Diagnostics & Research industry median Cyclically Adjusted PB Ratio is 1.80. Charles River Laboratories International's value of 4.29 is 138.3% above this industry median. Based on the distribution chart, Charles River Laboratories International ranks #104 out of 136 companies in the Medical Diagnostics & Research industry, which is in the bottom quartile relative to peers. Overall, Charles River Laboratories International has a GF Score™ of 70/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Charles River Laboratories International's Cyclically Adjusted PB Ratio compare to RVTY and QGEN?
According to the Medical Diagnostics & Research industry distribution chart, Charles River Laboratories International ranks #104 out of 136 companies for Cyclically Adjusted PB Ratio. This places Charles River Laboratories International in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.80. Charles River Laboratories International's value of 4.29 is 138.3% above this benchmark. Historically, Charles River Laboratories International's own Cyclically Adjusted PB Ratio has ranged from 2.21 to 19.58 over the past decade. While the company's 10-year median is 6.24 vs. the industry median of 1.80, Charles River Laboratories International has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Medical Diagnostics & Research company?
The median Cyclically Adjusted PB Ratio among Medical Diagnostics & Research companies is 1.80, based on 136 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Charles River Laboratories International's current Cyclically Adjusted PB Ratio of 4.29 is 138.3% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Charles River Laboratories International and its competitors. For the Medical Diagnostics & Research industry, the median Cyclically Adjusted PB Ratio is 1.80 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Charles River Laboratories International's current Cyclically Adjusted PB Ratio is 4.29, which is 31% below median its own 10-year median of 6.24. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Charles River Laboratories International stock overvalued right now?
Based on GuruFocus' analysis, Charles River Laboratories International (CRL) is currently considered Modestly Overvalued. The stock's GF Value™ is $194.04, compared to a current price of $219.40 — trading 13.1% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 4.29, which is 31% below median its 10-year median of 6.24 and 138.3% above the Medical Diagnostics & Research industry median of 1.80. Charles River Laboratories International's overall GF Score™ is 70/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Charles River Laboratories International (CRL), the current Cyclically Adjusted PB Ratio is 4.29 as of Jul. 21, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Charles River Laboratories International (CRL) Overvalued in 2026?
Based on GuruFocus' analysis, Charles River Laboratories International stock appears to be overvalued.
The current stock price of $219.40 is trading 13.1% above its estimated GF Value™ of $194.04.
GuruFocus considers Charles River Laboratories International to be Modestly Overvalued.
Key valuation signals for CRL:
Cyclically Adjusted PB Ratio: 4.29 (31% below median its 10-year median of 6.24)
GF Value™: $194.04 vs. price of $219.40 (13.1% above fair value)
Industry Position: 138.3% above the Medical Diagnostics & Research median (#104 of 136)
No single metric tells the full story. See the CRL stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Charles River Laboratories International Business Description
Charles River Laboratories was founded in 1947 and is a leading provider of drug discovery and development services. The company's research model & services segment is the leading provider of animal models for laboratory testing, which breeds and delivers animal research models with specific genetic characteristics for preclinical studies around the world. The discovery & safety assessment segment includes services required to take a drug through the early development process, including discovery services. The manufacturing support segment includes microbial solutions, which provides in vitro (non-animal) testing products, biologics testing services, and avian vaccine services.
70GF Score
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