CRL (Charles River Laboratories International) E10: $5.51 (As of Mar. 2026)

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CRL Charles River Laboratories International Inc CRL
70 GF Score
Price $219.40
GF Value $194.04
Valuation Modestly Overvalued
! 8 Warning Signs
View Full Analysis

What is Charles River Laboratories International E10?

Charles River Laboratories International CRL -0.14% 70 E10 is $5.51 as of Mar. 2026. GuruFocus rates CRL with a GF Score™ of 70/100 and a GF Value™ of $194.04 (Modestly Overvalued). The stock has 8 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Charles River Laboratories International's adjusted earnings per share data for the three months ended in Mar. 2026 was $-0.300. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $5.51 for the trailing ten years ended in Mar. 2026.

During the past 12 months, Charles River Laboratories International's average E10 Growth Rate was -10.40% per year. During the past 3 years, the average E10 Growth Rate was 0.70% per year. During the past 5 years, the average E10 Growth Rate was 9.40% per year. During the past 10 years, the average E10 Growth Rate was 48.60% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of Charles River Laboratories International was 238.50% per year. The lowest was 0.70% per year. And the median was 32.60% per year.

As of today (2026-07-21), Charles River Laboratories International's current stock price is $219.40. Charles River Laboratories International's E10 for the quarter that ended in Mar. 2026 was $5.51. Charles River Laboratories International's Shiller PE Ratio of today is 39.82.

During the past 13 years, the highest Shiller PE Ratio of Charles River Laboratories International was 231.39. The lowest was 16.22. And the median was 64.41.


Charles River Laboratories International  (NYSE:CRL) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

Charles River Laboratories International's Shiller P/E Ratio of today is calculated as

Shiller PE Ratio=Share Price/E10
=219.40/5.51
=39.82

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Shiller P/E Ratio of Charles River Laboratories International was 231.39. The lowest was 16.22. And the median was 64.41.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Charles River Laboratories International E10 Related Terms


Charles River Laboratories International E10 Historical Data

* Premium members only.

The historical data trend for Charles River Laboratories International's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Charles River Laboratories International E10 Chart

Charles River Laboratories International Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 4.45 5.43 6.26 6.11 5.55

Charles River Laboratories International Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 6.15 6.17 6.21 5.55 5.51

CRL vs RVTY, QGEN, ICLR: E10 Comparison

For the Diagnostics & Research subindustry, Charles River Laboratories International's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Charles River Laboratories International Shiller PE Ratio vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Charles River Laboratories International's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Charles River Laboratories International's Shiller PE Ratio falls into.


CRL
70GF Score
Charles River Laboratories International Inc CRL
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Charles River Laboratories International E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Charles River Laboratories International's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=-0.3/330.2130*330.2130
=-0.300

Current CPI (Mar. 2026) = 330.2130.

Charles River Laboratories International Quarterly Data

per share eps CPI Adj_EPS
201606 0.730 241.018 1.000
201609 0.790 241.428 1.081
201612 0.930 241.432 1.272
201703 0.970 243.801 1.314
201706 1.120 244.955 1.510
201709 1.080 246.819 1.445
201712 -0.630 246.524 -0.844
201803 1.080 249.554 1.429
201806 1.100 251.989 1.441
201809 1.220 252.439 1.596
201812 1.210 251.233 1.590
201903 1.110 254.202 1.442
201906 0.880 256.143 1.134
201909 1.460 256.759 1.878
201912 1.610 256.974 2.069
202003 1.020 258.115 1.305
202006 1.340 257.797 1.716
202009 2.030 260.280 2.575
202012 2.810 260.474 3.562
202103 1.200 264.877 1.496
202106 1.720 271.696 2.090
202109 2.010 274.310 2.420
202112 2.670 278.802 3.162
202203 1.810 287.504 2.079
202206 2.130 296.311 2.374
202209 1.880 296.808 2.092
202212 3.650 296.797 4.061
202303 2.010 301.836 2.199
202306 1.890 305.109 2.046
202309 1.690 307.789 1.813
202312 3.640 306.746 3.918
202403 1.300 312.332 1.374
202406 1.740 314.175 1.829
202409 1.330 315.301 1.393
202412 -4.220 315.605 -4.415
202503 0.500 319.799 0.516
202506 1.060 322.561 1.085
202509 1.100 324.800 1.118
202512 -5.620 324.054 -5.727
202603 -0.300 330.213 -0.300

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $5.51 mean?
Charles River Laboratories International (CRL) has a E10 of $5.51 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Charles River Laboratories International and its competitors.
Is Charles River Laboratories International's E10 too high?
Charles River Laboratories International's current E10 is $5.51. Overall, Charles River Laboratories International has a GF Score™ of 70/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Charles River Laboratories International's E10 compare to RVTY and QGEN?
Charles River Laboratories International's E10 of $5.51 can be compared against companies in the Medical Diagnostics & Research industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Medical Diagnostics & Research company?
A good E10 depends on the Medical Diagnostics & Research industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Charles River Laboratories International and its competitors. Charles River Laboratories International's current E10 is $5.51. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Charles River Laboratories International stock overvalued right now?
Based on GuruFocus' analysis, Charles River Laboratories International (CRL) is currently considered Modestly Overvalued. The stock's GF Value™ is $194.04, compared to a current price of $219.40 — trading 13.1% above its estimated fair value. The current E10 is $5.51. Charles River Laboratories International's overall GF Score™ is 70/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Charles River Laboratories International (CRL), the current E10 is $5.51 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Charles River Laboratories International (CRL) Overvalued in 2026?

Based on GuruFocus' analysis, Charles River Laboratories International stock appears to be overvalued. The current stock price of $219.40 is trading 13.1% above its estimated GF Value™ of $194.04. GuruFocus considers Charles River Laboratories International to be Modestly Overvalued.

Key valuation signals for CRL:

  • E10: $5.51
  • GF Value™: $194.04 vs. price of $219.40 (13.1% above fair value)
  • GF Score™: 70/100 with 8 warning signs

No single metric tells the full story. See the CRL stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Charles River Laboratories International Business Description

Other Exchanges RV6:Germany
Address 251 Ballardvale Street, Wilmington, MA, USA, 01887
Charles River Laboratories was founded in 1947 and is a leading provider of drug discovery and development services. The company's research model & services segment is the leading provider of animal models for laboratory testing, which breeds and delivers animal research models with specific genetic characteristics for preclinical studies around the world. The discovery & safety assessment segment includes services required to take a drug through the early development process, including discovery services. The manufacturing support segment includes microbial solutions, which provides in vitro (non-animal) testing products, biologics testing services, and avian vaccine services.
70GF Score

Get the complete analysis for CRL

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$219.40
Price
$194.04
GF Value