CRL (Charles River Laboratories International) Shiller PE Ratio: 50.87 (As of Sep. 12, 2026) — 20% Below Median

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CRL Charles River Laboratories International Inc CRL
69 GF Score
Price $278.26
GF Value $194.25
Valuation Significantly Overvalued
! 9 Warning Signs
View Full Analysis

What is Charles River Laboratories International Shiller PE Ratio?

Charles River Laboratories International CRL +1.93% 69 Shiller PE Ratio is 50.87 as of Sep. 12, 2026, which is 20% below its 10-year median of 63.94. GuruFocus rates CRL with a GF Score™ of 69/100 and a GF Value™ of $194.25 (Significantly Overvalued). The stock has 9 warning signs investors should review. Among 78 Medical Diagnostics & Research companies, Charles River Laboratories International ranks worse than 75.64% on this metric.

As of today (2026-09-12), Charles River Laboratories International's current share price is $278.26. Charles River Laboratories International's E10 for the quarter that ended in Jun. 2026 was $5.47. Charles River Laboratories International's Shiller PE Ratio for today is 50.87.

The historical rank and industry rank for Charles River Laboratories International's Shiller PE Ratio or its related term are showing as below:

CRL' s Shiller PE Ratio Range Over the Past 10 Years
Min: 16.22   Med: 63.94   Max: 224.23
Current: 50.85

During the past years, Charles River Laboratories International's highest Shiller PE Ratio was 224.23. The lowest was 16.22. And the median was 63.94.

CRL's Shiller PE Ratio is ranked worse than
75.64% of 78 companies
in the Medical Diagnostics & Research industry
Industry Median: 28.56 vs CRL: 50.85

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Charles River Laboratories International's adjusted earnings per share data for the three months ended in Jun. 2026 was $-0.030. Add all the adjusted EPS for the past 10 years together and divide 10 will get our E10, which is $5.47 for the trailing ten years ended in Jun. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Charles River Laboratories International  (NYSE:CRL) Shiller PE Ratio Explanation

Compared with the regular PE Ratio, which works poorly for cyclical businesses, the Shiller PE Ratio smoothed out the fluctuations of profit margins during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Shiller PE Ratio should give similar results to regular PE Ratio.

Compared with the PS Ratio, the Shiller PE Ratio makes the comparison between different industries more meaningful.


Be Aware

Shiller PE Ratio assumes that over the long term, businesses and profitability revert to their means. If a company's business model does not work in the future compared with the past, Shiller PE Ratio and PS Ratio will give false valuations.


Charles River Laboratories International Shiller PE Ratio Related Terms


Charles River Laboratories International Shiller PE Ratio Historical Data

* Premium members only.

The historical data trend for Charles River Laboratories International's Shiller PE Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Charles River Laboratories International Shiller PE Ratio Chart

Charles River Laboratories International Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Shiller PE Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 84.62 40.10 37.75 30.23 35.96

Charles River Laboratories International Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Shiller PE Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 24.59 25.18 35.96 31.28 41.44

CRL vs RVTY, ICLR, MEDP: Shiller PE Ratio Comparison

For the Diagnostics & Research subindustry, Charles River Laboratories International's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Charles River Laboratories International Shiller PE Ratio vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Charles River Laboratories International's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Charles River Laboratories International's Shiller PE Ratio falls into.


CRL
69GF Score
Charles River Laboratories International Inc CRL
Shiller PE Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Charles River Laboratories International Shiller PE Ratio Calculation

For Shiller PE Ratio, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller PE Ratio is also called PE10.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

Charles River Laboratories International's Shiller PE Ratio for today is calculated as

Shiller PE Ratio=Share Price/ E10
=278.26/5.47
=50.87

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Charles River Laboratories International's E10 for the quarter that ended in Jun. 2026 is calculated as:

For example, Charles River Laboratories International's adjusted earnings per share data for the three months ended in Jun. 2026 was:

Adj_EPS=Earnings per Share (Diluted)/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=-0.03/333.9520*333.9520
=-0.030

Current CPI (Jun. 2026) = 333.9520.

Charles River Laboratories International Quarterly Data

Earnings per Share (Diluted) CPI Adj_EPS
201609 0.790 241.428 1.093
201612 0.930 241.432 1.286
201703 0.970 243.801 1.329
201706 1.120 244.955 1.527
201709 1.080 246.819 1.461
201712 -0.630 246.524 -0.853
201803 1.080 249.554 1.445
201806 1.100 251.989 1.458
201809 1.220 252.439 1.614
201812 1.210 251.233 1.608
201903 1.110 254.202 1.458
201906 0.880 256.143 1.147
201909 1.460 256.759 1.899
201912 1.610 256.974 2.092
202003 1.020 258.115 1.320
202006 1.340 257.797 1.736
202009 2.030 260.280 2.605
202012 2.810 260.474 3.603
202103 1.200 264.877 1.513
202106 1.720 271.696 2.114
202109 2.010 274.310 2.447
202112 2.670 278.802 3.198
202203 1.810 287.504 2.102
202206 2.130 296.311 2.401
202209 1.880 296.808 2.115
202212 3.650 296.797 4.107
202303 2.010 301.836 2.224
202306 1.890 305.109 2.069
202309 1.690 307.789 1.834
202312 3.640 306.746 3.963
202403 1.300 312.332 1.390
202406 1.740 314.175 1.850
202409 1.330 315.301 1.409
202412 -4.220 315.605 -4.465
202503 0.500 319.799 0.522
202506 1.060 322.561 1.097
202509 1.100 324.800 1.131
202512 -5.620 324.054 -5.792
202603 -0.300 330.213 -0.303
202606 -0.030 333.952 -0.030

Add all the adjusted EPS together and divide 10 will get our E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

Frequently Asked Questions Learn more about Shiller PE Ratio →
What does a Shiller PE Ratio of 50.87 mean?
Charles River Laboratories International (CRL) has a Shiller PE Ratio of 50.87 as of Sep. 12, 2026. Shiller price-earnings ratio is the ratio of share price to a company's inflation-adjusted earnings over a 10-year period. View historical data on Charles River Laboratories International and its competitors. This is 20% below median its historical median of 63.94. Over the past decade, Charles River Laboratories International's Shiller PE Ratio has ranged from 16.22 to 224.23. According to the industry distribution chart, Charles River Laboratories International ranks #59 out of 78 companies in the Medical Diagnostics & Research industry, placing it in the top 75.6%.
Is Charles River Laboratories International's Shiller PE Ratio too high?
Charles River Laboratories International's current Shiller PE Ratio of 50.87 is 20% below median its 10-year median of 63.94. Over the past 10 years, this metric has ranged from a low of 16.22 to a high of 224.23. The Medical Diagnostics & Research industry median Shiller PE Ratio is 28.56. Charles River Laboratories International's value of 50.87 is 78.1% above this industry median. Based on the distribution chart, Charles River Laboratories International ranks #59 out of 78 companies in the Medical Diagnostics & Research industry, which is in the bottom quartile relative to peers. Overall, Charles River Laboratories International has a GF Score™ of 69/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Charles River Laboratories International's Shiller PE Ratio compare to RVTY and ICLR?
According to the Medical Diagnostics & Research industry distribution chart, Charles River Laboratories International ranks #59 out of 78 companies for Shiller PE Ratio. This places Charles River Laboratories International in the lower half of its industry. The industry median Shiller PE Ratio is 28.56. Charles River Laboratories International's value of 50.87 is 78.1% above this benchmark. Historically, Charles River Laboratories International's own Shiller PE Ratio has ranged from 16.22 to 224.23 over the past decade. While the company's 10-year median is 63.94 vs. the industry median of 28.56, Charles River Laboratories International has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Shiller PE Ratio for a Medical Diagnostics & Research company?
The median Shiller PE Ratio among Medical Diagnostics & Research companies is 28.56, based on 78 companies in the industry. Companies in the top quartile (top 25%) have a Shiller PE Ratio significantly above this median, while those in the bottom quartile fall well below. However, Shiller PE Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Charles River Laboratories International's current Shiller PE Ratio of 50.87 is 78.1% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Shiller PE Ratio mean?
A high Shiller PE Ratio can signal that a stock is expensive relative to its fundamentals. Shiller price-earnings ratio is the ratio of share price to a company's inflation-adjusted earnings over a 10-year period. View historical data on Charles River Laboratories International and its competitors. For the Medical Diagnostics & Research industry, the median Shiller PE Ratio is 28.56 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Charles River Laboratories International's current Shiller PE Ratio is 50.87, which is 20% below median its own 10-year median of 63.94. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Charles River Laboratories International stock overvalued right now?
Based on GuruFocus' analysis, Charles River Laboratories International (CRL) is currently considered Significantly Overvalued. The stock's GF Value™ is $194.25, compared to a current price of $278.26 — trading 43.2% above its estimated fair value. The current Shiller PE Ratio is 50.87, which is 20% below median its 10-year median of 63.94 and 78.1% above the Medical Diagnostics & Research industry median of 28.56. Charles River Laboratories International's overall GF Score™ is 69/100 with 9 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Shiller PE Ratio calculated?
Shiller PE Ratio is calculated from a company's financial statements. For Charles River Laboratories International (CRL), the current Shiller PE Ratio is 50.87 as of Sep. 12, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Charles River Laboratories International (CRL) Overvalued in 2026?

Based on GuruFocus' analysis, Charles River Laboratories International stock appears to be overvalued. The current stock price of $278.26 is trading 43.2% above its estimated GF Value™ of $194.25. GuruFocus considers Charles River Laboratories International to be Significantly Overvalued.

Key valuation signals for CRL:

  • Shiller PE Ratio: 50.87 (20% below median its 10-year median of 63.94)
  • GF Value™: $194.25 vs. price of $278.26 (43.2% above fair value)
  • GF Score™: 69/100 with 9 warning signs
  • Industry Position: 78.1% above the Medical Diagnostics & Research median (#59 of 78)

No single metric tells the full story. See the CRL stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Charles River Laboratories International Business Description

Other Exchanges RV6:Germany
Address 251 Ballardvale Street, Wilmington, MA, USA, 01887
Charles River Laboratories was founded in 1947 and is a leading provider of drug discovery and development services. The company's research model & services segment is the leading provider of animal models for laboratory testing, which breeds and delivers animal research models with specific genetic characteristics for preclinical studies around the world. The discovery & safety assessment segment includes services required to take a drug through the early development process, including discovery services. The manufacturing support segment includes microbial solutions, which provides in vitro (non-animal) testing products, biologics testing services, and avian vaccine services.
69GF Score

Get the complete analysis for CRL

Shiller PE Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$278.26
Price
$194.25
GF Value