EDSA (Edesa Biotech) Cyclically Adjusted PB Ratio: 0.09 (As of Jul. 13, 2026) — 29% Above Median

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EDSA Edesa Biotech Inc EDSA
31 GF Score
Price $6.81
! 2 Warning Signs
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What is Edesa Biotech Cyclically Adjusted PB Ratio?

Edesa Biotech EDSA -2.85% 31 Cyclically Adjusted PB Ratio is 0.09 as of Jul. 13, 2026, which is 29% above its 10-year median of 0.07. GuruFocus rates EDSA with a GF Score™ of 31/100. The stock has 2 warning signs investors should review. Among 697 Biotechnology companies, Edesa Biotech ranks better than 89.96% on this metric.

As of today (2026-07-13), Edesa Biotech's current share price is $6.81. Edesa Biotech's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was $77.01. Edesa Biotech's Cyclically Adjusted PB Ratio for today is 0.09.

The historical rank and industry rank for Edesa Biotech's Cyclically Adjusted PB Ratio or its related term are showing as below:

EDSA' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.01   Med: 0.07   Max: 0.34
Current: 0.09

During the past years, Edesa Biotech's highest Cyclically Adjusted PB Ratio was 0.34. The lowest was 0.01. And the median was 0.07.

EDSA's Cyclically Adjusted PB Ratio is ranked better than
89.96% of 697 companies
in the Biotechnology industry
Industry Median: 1.62 vs EDSA: 0.09

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Edesa Biotech's adjusted book value per share data for the three months ended in Mar. 2026 was $0.205. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $77.01 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Edesa Biotech  (NAS:EDSA) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Edesa Biotech Cyclically Adjusted PB Ratio Related Terms


Edesa Biotech Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Edesa Biotech's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Edesa Biotech Cyclically Adjusted PB Ratio Chart

Edesa Biotech Annual Data
Trend Sep16 Sep17 Sep18 Sep19 Sep20 Sep21 Sep22 Sep23 Sep24 Sep25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.31 0.04 0.02 0.03 0.03

Edesa Biotech Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.02 0.02 0.03 0.02 0.07

EDSA vs ACET, HRTX, ENTX: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Edesa Biotech's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Edesa Biotech Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Edesa Biotech's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Edesa Biotech's Cyclically Adjusted PB Ratio falls into.


EDSA
31GF Score
Edesa Biotech Inc EDSA
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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Edesa Biotech Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Edesa Biotech's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=6.81/77.01
=0.09

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Edesa Biotech's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Edesa Biotech's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.205/132.2623*132.2623
=0.205

Current CPI (Mar. 2026) = 132.2623.

Edesa Biotech Quarterly Data

Book Value per Share CPI Adj_Book
201606 264.172 102.002 342.544
201609 362.176 101.765 470.716
201612 319.559 101.449 416.621
201703 287.941 102.634 371.065
201706 238.806 103.029 306.565
201709 205.528 103.345 263.038
201712 167.194 103.345 213.978
201803 131.667 105.004 165.847
201806 97.535 105.557 122.211
201809 88.874 105.636 111.275
201812 78.016 105.399 97.900
201903 65.118 106.979 80.508
201906 5.796 107.690 7.118
201909 4.903 107.611 6.026
201912 3.950 107.769 4.848
202003 5.475 107.927 6.709
202006 4.220 108.401 5.149
202009 4.826 108.164 5.901
202012 5.246 108.559 6.391
202103 10.187 110.298 12.216
202106 8.344 111.720 9.878
202109 6.876 112.905 8.055
202112 5.463 113.774 6.351
202203 7.707 117.646 8.665
202206 5.359 120.806 5.867
202209 3.946 120.648 4.326
202212 3.715 120.964 4.062
202303 3.140 122.702 3.385
202306 2.633 124.203 2.804
202309 2.292 125.230 2.421
202312 1.847 125.072 1.953
202403 1.345 126.258 1.409
202406 0.883 127.522 0.916
202409 0.610 127.285 0.634
202412 0.370 127.364 0.384
202503 0.905 129.181 0.927
202506 0.699 129.892 0.712
202509 0.447 130.287 0.454
202512 0.559 130.366 0.567
202603 0.205 132.262 0.205

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.09 mean?
Edesa Biotech (EDSA) has a Cyclically Adjusted PB Ratio of 0.09 as of Jul. 13, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Edesa Biotech and its competitors. This is 29% above median its historical median of 0.07. Over the past decade, Edesa Biotech's Cyclically Adjusted PB Ratio has ranged from 0.01 to 0.34. According to the industry distribution chart, Edesa Biotech ranks #70 out of 697 companies in the Biotechnology industry, placing it in the top 10%.
Is Edesa Biotech's Cyclically Adjusted PB Ratio too high?
Edesa Biotech's current Cyclically Adjusted PB Ratio of 0.09 is 29% above median its 10-year median of 0.07. Over the past 10 years, this metric has ranged from a low of 0.01 to a high of 0.34. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.62. Edesa Biotech's value of 0.09 is 94.4% below this industry median. Based on the distribution chart, Edesa Biotech ranks #70 out of 697 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Edesa Biotech has a GF Score™ of 31/100, reflecting its overall financial health beyond just this single metric.
How does Edesa Biotech's Cyclically Adjusted PB Ratio compare to ACET and HRTX?
According to the Biotechnology industry distribution chart, Edesa Biotech ranks #70 out of 697 companies for Cyclically Adjusted PB Ratio. This places Edesa Biotech in the top 10% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PB Ratio is 1.62. Edesa Biotech's value of 0.09 is 94.4% below this benchmark. Historically, Edesa Biotech's own Cyclically Adjusted PB Ratio has ranged from 0.01 to 0.34 over the past decade. While the company's 10-year median is 0.07 vs. the industry median of 1.62, Edesa Biotech has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.62, based on 697 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Edesa Biotech's current Cyclically Adjusted PB Ratio of 0.09 is 94.4% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Edesa Biotech and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.62 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Edesa Biotech's current Cyclically Adjusted PB Ratio is 0.09, which is 29% above median its own 10-year median of 0.07. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Edesa Biotech stock overvalued right now?
Edesa Biotech (EDSA) has a current Cyclically Adjusted PB Ratio of 0.09. The current Cyclically Adjusted PB Ratio is 0.09, which is 29% above median its 10-year median of 0.07 and 94.4% below the Biotechnology industry median of 1.62. Edesa Biotech's overall GF Score™ is 31/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Edesa Biotech (EDSA), the current Cyclically Adjusted PB Ratio is 0.09 as of Jul. 13, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Edesa Biotech Business Description

Address 100 Spy Court, Markham, ON, CAN, L3R 5H6
Edesa Biotech Inc is a biotechnology company focused on inflammatory and immune-related diseases. It is involved in exploring novel ways to treat these diseases, including alternatives to topical steroids, which can have side effects. The company's product candidate, EB06, is an anti-CXCL10 monoclonal antibody candidate and is being developed as a therapy for vitiligo, a common autoimmune disorder that causes the skin to lose its color in patches. The other drug candidates in its product pipeline include EB05, EB07, and EB01 which are in their different phases of development.
31GF Score

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$6.81
Price