HLTRF (HLS Therapeutics) Cyclically Adjusted PB Ratio: 0.64 (As of Aug. 12, 2026) — 54% Below Median

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HLTRF HLS Therapeutics Inc HLTRF
56 GF Score
Price $2.75
GF Value $3.06
Valuation Modestly Undervalued
! 4 Warning Signs
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What is HLS Therapeutics Cyclically Adjusted PB Ratio?

HLS Therapeutics HLTRF 56 Cyclically Adjusted PB Ratio is 0.64 as of Aug. 12, 2026, which is 54% below its 10-year median of 1.39. GuruFocus rates HLTRF with a GF Score™ of 56/100 and a GF Value™ of $3.06 (Modestly Undervalued). The stock has 4 warning signs investors should review. Among 729 Drug Manufacturers companies, HLS Therapeutics ranks better than 82.58% on this metric.

As of today (2026-08-12), HLS Therapeutics's current share price is $2.75. HLS Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was $4.28. HLS Therapeutics's Cyclically Adjusted PB Ratio for today is 0.64.

The historical rank and industry rank for HLS Therapeutics's Cyclically Adjusted PB Ratio or its related term are showing as below:

HLTRF' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.51   Med: 1.39   Max: 6.48
Current: 0.65

During the past years, HLS Therapeutics's highest Cyclically Adjusted PB Ratio was 6.48. The lowest was 0.51. And the median was 1.39.

HLTRF's Cyclically Adjusted PB Ratio is ranked better than
82.58% of 729 companies
in the Drug Manufacturers industry
Industry Median: 1.8 vs HLTRF: 0.65

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

HLS Therapeutics's adjusted book value per share data for the three months ended in Mar. 2026 was $1.873. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $4.28 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


HLS Therapeutics  (OTCPK:HLTRF) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


HLS Therapeutics Cyclically Adjusted PB Ratio Related Terms


HLS Therapeutics Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for HLS Therapeutics's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

HLS Therapeutics Cyclically Adjusted PB Ratio Chart

HLS Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 3.03 1.76 0.66 0.64 0.78

HLS Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.75 0.78 0.92 0.78 0.70

HLTRF vs ZTS: Cyclically Adjusted PB Ratio Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, HLS Therapeutics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


HLS Therapeutics Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, HLS Therapeutics's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where HLS Therapeutics's Cyclically Adjusted PB Ratio falls into.


HLTRF
56GF Score
HLS Therapeutics Inc HLTRF
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

HLS Therapeutics Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

HLS Therapeutics's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=2.75/4.28
=0.64

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

HLS Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, HLS Therapeutics's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=1.873/132.2623*132.2623
=1.873

Current CPI (Mar. 2026) = 132.2623.

HLS Therapeutics Quarterly Data

Book Value per Share CPI Adj_Book
201606 2.029 102.002 2.631
201609 1.989 101.765 2.585
201612 1.924 101.449 2.508
201703 1.918 102.634 2.472
201706 1.948 103.029 2.501
201709 2.018 103.345 2.583
201712 6.576 103.345 8.416
201803 6.916 105.004 8.711
201806 6.735 105.557 8.439
201809 6.113 105.636 7.654
201812 5.807 105.399 7.287
201903 5.750 106.979 7.109
201906 6.281 107.690 7.714
201909 6.133 107.611 7.538
201912 5.737 107.769 7.041
202003 5.297 107.927 6.491
202006 5.311 108.401 6.480
202009 5.319 108.164 6.504
202012 5.319 108.559 6.480
202103 5.262 110.298 6.310
202106 5.267 111.720 6.235
202109 5.079 112.905 5.950
202112 4.953 113.774 5.758
202203 4.898 117.646 5.507
202206 4.455 120.806 4.877
202209 4.056 120.648 4.446
202212 3.873 120.964 4.235
202303 3.675 122.702 3.961
202306 3.450 124.203 3.674
202309 3.166 125.230 3.344
202312 3.055 125.072 3.231
202403 2.793 126.258 2.926
202406 2.601 127.522 2.698
202409 2.495 127.285 2.593
202412 2.244 127.364 2.330
202503 2.105 129.181 2.155
202506 2.114 129.892 2.153
202509 1.974 130.287 2.004
202512 1.972 130.366 2.001
202603 1.873 132.262 1.873

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.64 mean?
HLS Therapeutics (HLTRF) has a Cyclically Adjusted PB Ratio of 0.64 as of Aug. 12, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on HLS Therapeutics and its competitors. This is 54% below median its historical median of 1.39. Over the past decade, HLS Therapeutics' Cyclically Adjusted PB Ratio has ranged from 0.51 to 6.48. According to the industry distribution chart, HLS Therapeutics ranks #127 out of 729 companies in the Drug Manufacturers industry, placing it in the top 17.4%.
Is HLS Therapeutics' Cyclically Adjusted PB Ratio too high?
HLS Therapeutics' current Cyclically Adjusted PB Ratio of 0.64 is 54% below median its 10-year median of 1.39. Over the past 10 years, this metric has ranged from a low of 0.51 to a high of 6.48. The Drug Manufacturers industry median Cyclically Adjusted PB Ratio is 1.80. HLS Therapeutics' value of 0.64 is 64.4% below this industry median. Based on the distribution chart, HLS Therapeutics ranks #127 out of 729 companies in the Drug Manufacturers industry, which is in the top quartile — a strong position relative to peers. Overall, HLS Therapeutics has a GF Score™ of 56/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does HLS Therapeutics' Cyclically Adjusted PB Ratio compare to ZTS?
According to the Drug Manufacturers industry distribution chart, HLS Therapeutics ranks #127 out of 729 companies for Cyclically Adjusted PB Ratio. This places HLS Therapeutics in the top 17% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PB Ratio is 1.80. HLS Therapeutics' value of 0.64 is 64.4% below this benchmark. Historically, HLS Therapeutics' own Cyclically Adjusted PB Ratio has ranged from 0.51 to 6.48 over the past decade. While the company's 10-year median is 1.39 vs. the industry median of 1.80, HLS Therapeutics has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PB Ratio among Drug Manufacturers companies is 1.80, based on 729 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. HLS Therapeutics's current Cyclically Adjusted PB Ratio of 0.64 is 64.4% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on HLS Therapeutics and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PB Ratio is 1.80 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. HLS Therapeutics's current Cyclically Adjusted PB Ratio is 0.64, which is 54% below median its own 10-year median of 1.39. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is HLS Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, HLS Therapeutics (HLTRF) is currently considered Modestly Undervalued. The stock's GF Value™ is $3.06, compared to a current price of $2.75 — trading 10.1% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 0.64, which is 54% below median its 10-year median of 1.39 and 64.4% below the Drug Manufacturers industry median of 1.80. HLS Therapeutics' overall GF Score™ is 56/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For HLS Therapeutics (HLTRF), the current Cyclically Adjusted PB Ratio is 0.64 as of Aug. 12, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is HLS Therapeutics (HLTRF) Overvalued in 2026?

Based on GuruFocus' analysis, HLS Therapeutics stock appears to be undervalued. The current stock price of $2.75 is trading 10.1% below its estimated GF Value™ of $3.06. GuruFocus considers HLS Therapeutics to be Modestly Undervalued.

Key valuation signals for HLTRF:

  • Cyclically Adjusted PB Ratio: 0.64 (54% below median its 10-year median of 1.39)
  • GF Value™: $3.06 vs. price of $2.75 (10.1% below fair value)
  • GF Score™: 56/100 with 4 warning signs
  • Industry Position: 64.4% below the Drug Manufacturers median (#127 of 729)

No single metric tells the full story. See the HLTRF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


HLS Therapeutics Business Description

Other Exchanges 74D:GermanyHLS:Canada
Address 10 Carlson Court, Suite 701, Etobicoke, Toronto, ON, CAN, M9W 6L2
HLS Therapeutics Inc is a specialty pharmaceutical company. It is focused on the acquisition and commercialization of branded pharmaceutical products in the North American markets. The company's products include Clozaril, Vascepa, CSAN Pronto, and others. The company earns revenue in the form of product sales and royalties, out of which product sales contribute to the majority of the revenue. The company operates in Canada, the United States, and the Rest of world, with the majority of its revenue generated from Canada.
56GF Score

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Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$2.75
Price
$3.06
GF Value