Pfizer (MEX:PFE) Cyclically Adjusted PB Ratio: 1.64 (As of Aug. 18, 2026) — 42% Below Median

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MEX:PFE Pfizer Inc MEX:PFE
68 GF Score
Price MXN458.28
GF Value MXN452.48
Valuation Fairly Valued
! 7 Warning Signs
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What is Pfizer Cyclically Adjusted PB Ratio?

Pfizer MEX:PFE 68 Cyclically Adjusted PB Ratio is 1.64 as of Aug. 18, 2026, which is 42% below its 10-year median of 2.85. GuruFocus rates MEX:PFE with a GF Score™ of 68/100 and a GF Value™ of MXN452.48 (Fairly Valued). The stock has 7 warning signs investors should review. Among 707 Drug Manufacturers companies, Pfizer ranks better than 51.91% on this metric.

As of today (2026-08-18), Pfizer's current share price is MXN458.28. Pfizer's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was MXN279.49. Pfizer's Cyclically Adjusted PB Ratio for today is 1.64.

The historical rank and industry rank for Pfizer's Cyclically Adjusted PB Ratio or its related term are showing as below:

MEX:PFE' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 1.44   Med: 2.85   Max: 4.7
Current: 1.68

During the past years, Pfizer's highest Cyclically Adjusted PB Ratio was 4.70. The lowest was 1.44. And the median was 2.85.

MEX:PFE's Cyclically Adjusted PB Ratio is ranked better than
51.91% of 707 companies
in the Drug Manufacturers industry
Industry Median: 1.76 vs MEX:PFE: 1.68

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Pfizer's adjusted book value per share data for the three months ended in Jun. 2026 was MXN260.811. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is MXN279.49 for the trailing ten years ended in Jun. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Pfizer  (MEX:PFE) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Pfizer Cyclically Adjusted PB Ratio Related Terms


Pfizer Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Pfizer's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Pfizer Cyclically Adjusted PB Ratio Chart

Pfizer Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 4.58 3.69 1.98 1.77 1.61

Pfizer Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.58 1.65 1.61 1.78 1.51

MEX:PFE vs BMY, GILD, AMGN: Cyclically Adjusted PB Ratio Comparison

For the Drug Manufacturers - General subindustry, Pfizer's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Pfizer Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Pfizer's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Pfizer's Cyclically Adjusted PB Ratio falls into.


MEX:PFE
68GF Score
Pfizer Inc MEX:PFE
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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Pfizer Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Pfizer's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=458.28/279.49
=1.64

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Pfizer's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, Pfizer's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book=Book Value per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=260.811/333.9520*333.9520
=260.811

Current CPI (Jun. 2026) = 333.9520.

Pfizer Quarterly Data

Book Value per Share CPI Adj_Book
201609 201.631 241.428 278.903
201612 202.162 241.432 279.633
201703 184.688 243.801 252.981
201706 177.330 244.955 241.757
201709 184.954 246.819 250.247
201712 234.160 246.524 317.203
201803 214.285 249.554 286.755
201806 233.825 251.989 309.880
201809 230.716 252.439 305.215
201812 217.706 251.233 289.386
201903 205.210 254.202 269.590
201906 205.662 256.143 268.136
201909 232.310 256.759 302.153
201912 215.135 256.974 279.580
202003 274.555 258.115 355.222
202006 267.377 257.797 346.362
202009 259.427 260.280 332.858
202012 225.962 260.474 289.704
202103 250.744 264.877 316.133
202106 249.019 271.696 306.079
202109 277.376 274.310 337.685
202112 281.797 278.802 337.539
202203 293.533 287.504 340.955
202206 313.687 296.311 353.535
202209 332.016 296.808 373.566
202212 332.088 296.797 373.661
202303 322.420 301.836 356.726
202306 300.721 305.109 329.149
202309 299.058 307.789 324.479
202312 267.613 306.746 291.348
202403 270.255 312.332 288.962
202406 283.534 314.175 301.382
202409 320.709 315.301 339.680
202412 324.605 315.605 343.475
202503 325.093 319.799 339.480
202506 293.746 322.561 304.119
202509 299.419 324.800 307.856
202512 273.841 324.054 282.205
202603 285.096 330.213 288.324
202606 260.811 333.952 260.811

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 1.64 mean?
Pfizer (MEX:PFE) has a Cyclically Adjusted PB Ratio of 1.64 as of Aug. 18, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Pfizer and its competitors. This is 42% below median its historical median of 2.85. Over the past decade, Pfizer's Cyclically Adjusted PB Ratio has ranged from 1.44 to 4.70. According to the industry distribution chart, Pfizer ranks #340 out of 707 companies in the Drug Manufacturers industry, placing it in the top 48.1%.
Is Pfizer's Cyclically Adjusted PB Ratio too high?
Pfizer's current Cyclically Adjusted PB Ratio of 1.64 is 42% below median its 10-year median of 2.85. Over the past 10 years, this metric has ranged from a low of 1.44 to a high of 4.70. The Drug Manufacturers industry median Cyclically Adjusted PB Ratio is 1.76. Pfizer's value of 1.64 is 6.8% below this industry median. Based on the distribution chart, Pfizer ranks #340 out of 707 companies in the Drug Manufacturers industry, which is above the industry midpoint. Overall, Pfizer has a GF Score™ of 68/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Pfizer's Cyclically Adjusted PB Ratio compare to BMY and GILD?
According to the Drug Manufacturers industry distribution chart, Pfizer ranks #340 out of 707 companies for Cyclically Adjusted PB Ratio. This puts Pfizer in the upper half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.76. Pfizer's value of 1.64 is 6.8% below this benchmark. Historically, Pfizer's own Cyclically Adjusted PB Ratio has ranged from 1.44 to 4.70 over the past decade. While the company's 10-year median is 2.85 vs. the industry median of 1.76, Pfizer has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PB Ratio among Drug Manufacturers companies is 1.76, based on 707 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Pfizer's current Cyclically Adjusted PB Ratio of 1.64 is 6.8% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Pfizer and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PB Ratio is 1.76 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Pfizer's current Cyclically Adjusted PB Ratio is 1.64, which is 42% below median its own 10-year median of 2.85. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Pfizer stock overvalued right now?
Based on GuruFocus' analysis, Pfizer (MEX:PFE) is currently considered Fairly Valued. The stock's GF Value™ is MXN452.48, compared to a current price of MXN458.28 — trading 1.3% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 1.64, which is 42% below median its 10-year median of 2.85 and 6.8% below the Drug Manufacturers industry median of 1.76. Pfizer's overall GF Score™ is 68/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Pfizer (MEX:PFE), the current Cyclically Adjusted PB Ratio is 1.64 as of Aug. 18, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Pfizer (MEX:PFE) Overvalued in 2026?

Based on GuruFocus' analysis, Pfizer stock appears to be overvalued. The current stock price of MXN458.28 is trading 1.3% above its estimated GF Value™ of MXN452.48. GuruFocus considers Pfizer to be Fairly Valued.

Key valuation signals for MEX:PFE:

  • Cyclically Adjusted PB Ratio: 1.64 (42% below median its 10-year median of 2.85)
  • GF Value™: MXN452.48 vs. price of MXN458.28 (1.3% above fair value)
  • GF Score™: 68/100 with 7 warning signs
  • Industry Position: 6.8% below the Drug Manufacturers median (#340 of 707)

No single metric tells the full story. See the MEX:PFE stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Pfizer Business Description

Address 66 Hudson Boulevard East, New York, NY, USA, 10001-2192
Pfizer is one of the world's largest pharmaceutical firms, with annual sales of roughly $60 billion. While it historically sold many types of healthcare products and chemicals, now prescription drugs and vaccines account for the majority of sales. Top sellers include pneumococcal vaccine Prevnar 13 and cardiology drugs Vyndaqel and Eliquis. Pfizer sells these products globally, with international sales representing 40% of total sales. Within international sales, emerging markets are a major contributor.
68GF Score

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Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN458.28
Price
MXN452.48
GF Value