Soiken Holdings (TSE:2385) Cyclically Adjusted PB Ratio: 0.97 (As of Aug. 31, 2026) — 46% Below Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

TSE:2385 Soiken Holdings Inc TSE:2385
55 GF Score
Price 円224.00
GF Value 円111.55
Valuation Significantly Overvalued
! 2 Warning Signs
View Full Analysis

What is Soiken Holdings Cyclically Adjusted PB Ratio?

Soiken Holdings TSE:2385 -0.44% 55 Cyclically Adjusted PB Ratio is 0.97 as of Aug. 31, 2026, which is 46% below its 10-year median of 1.79. GuruFocus rates TSE:2385 with a GF Score™ of 55/100 and a GF Value™ of 円111.55 (Significantly Overvalued). The stock has 2 warning signs investors should review. Among 681 Biotechnology companies, Soiken Holdings ranks better than 62.56% on this metric.

As of today (2026-08-31), Soiken Holdings's current share price is 円224.00. Soiken Holdings's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was 円230.21. Soiken Holdings's Cyclically Adjusted PB Ratio for today is 0.97.

The historical rank and industry rank for Soiken Holdings's Cyclically Adjusted PB Ratio or its related term are showing as below:

TSE:2385' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.54   Med: 1.79   Max: 6.13
Current: 0.97

During the past years, Soiken Holdings's highest Cyclically Adjusted PB Ratio was 6.13. The lowest was 0.54. And the median was 1.79.

TSE:2385's Cyclically Adjusted PB Ratio is ranked better than
62.56% of 681 companies
in the Biotechnology industry
Industry Median: 1.64 vs TSE:2385: 0.97

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Soiken Holdings's adjusted book value per share data for the three months ended in Mar. 2026 was 円234.791. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is 円230.21 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Soiken Holdings  (TSE:2385) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Soiken Holdings Cyclically Adjusted PB Ratio Related Terms


Soiken Holdings Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Soiken Holdings's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Soiken Holdings Cyclically Adjusted PB Ratio Chart

Soiken Holdings Annual Data
Trend Jun17 Jun18 Jun19 Jun20 Jun21 Jun22 Jun23 Jun24 Jun25 Jun26
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 1.82 1.50 0.78 0.75 0.00

Soiken Holdings Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.75 0.87 1.02 1.02 0.00

TSE:2385 vs VRTX, REGN, MRNA: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Soiken Holdings's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Soiken Holdings Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Soiken Holdings's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Soiken Holdings's Cyclically Adjusted PB Ratio falls into.


TSE:2385
55GF Score
Soiken Holdings Inc TSE:2385
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Soiken Holdings Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Soiken Holdings's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=224.00/230.21
=0.97

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Soiken Holdings's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Soiken Holdings's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=234.791/112.7000*112.7000
=234.791

Current CPI (Mar. 2026) = 112.7000.

Soiken Holdings Quarterly Data

Book Value per Share CPI Adj_Book
201603 160.986 97.900 185.323
201606 161.766 98.100 185.841
201609 157.788 98.000 181.456
201612 159.824 98.400 183.050
201703 165.421 98.100 190.040
201706 166.985 98.500 191.058
201709 161.091 98.800 183.755
201712 166.689 99.400 188.992
201803 171.707 99.200 195.074
201806 171.841 99.200 195.227
201809 163.811 99.900 184.800
201812 174.337 99.700 197.069
201903 185.290 99.700 209.450
201906 190.871 99.800 215.543
201909 178.191 100.100 200.621
201912 192.038 100.500 215.350
202003 201.874 100.300 226.832
202006 214.397 99.900 241.867
202009 211.050 99.900 238.091
202012 224.260 99.300 254.523
202103 231.220 99.900 260.846
202106 230.884 99.500 261.514
202109 226.345 100.100 254.836
202112 239.050 100.100 269.140
202203 247.675 101.100 276.093
202206 254.140 101.800 281.351
202209 249.665 103.100 272.912
202212 257.138 104.100 278.381
202303 268.110 104.400 289.425
202306 266.414 105.200 285.407
202309 241.263 106.200 256.030
202312 244.942 106.800 258.473
202403 241.629 107.200 254.026
202406 238.278 108.200 248.188
202412 229.780 110.700 233.931
202503 232.535 111.100 235.884
202506 230.223 111.700 232.284
202509 228.644 112.000 230.073
202512 231.633 113.000 231.018
202603 234.791 112.700 234.791

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.97 mean?
Soiken Holdings (TSE:2385) has a Cyclically Adjusted PB Ratio of 0.97 as of Aug. 31, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Soiken Holdings and its competitors. This is 46% below median its historical median of 1.79. Over the past decade, Soiken Holdings' Cyclically Adjusted PB Ratio has ranged from 0.54 to 6.13. According to the industry distribution chart, Soiken Holdings ranks #255 out of 681 companies in the Biotechnology industry, placing it in the top 37.4%.
Is Soiken Holdings' Cyclically Adjusted PB Ratio too high?
Soiken Holdings' current Cyclically Adjusted PB Ratio of 0.97 is 46% below median its 10-year median of 1.79. Over the past 10 years, this metric has ranged from a low of 0.54 to a high of 6.13. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.64. Soiken Holdings' value of 0.97 is 40.9% below this industry median. Based on the distribution chart, Soiken Holdings ranks #255 out of 681 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Soiken Holdings has a GF Score™ of 55/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Soiken Holdings' Cyclically Adjusted PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Soiken Holdings ranks #255 out of 681 companies for Cyclically Adjusted PB Ratio. This puts Soiken Holdings in the upper half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.64. Soiken Holdings' value of 0.97 is 40.9% below this benchmark. Historically, Soiken Holdings' own Cyclically Adjusted PB Ratio has ranged from 0.54 to 6.13 over the past decade. While the company's 10-year median is 1.79 vs. the industry median of 1.64, Soiken Holdings has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.64, based on 681 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Soiken Holdings's current Cyclically Adjusted PB Ratio of 0.97 is 40.9% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Soiken Holdings and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.64 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Soiken Holdings's current Cyclically Adjusted PB Ratio is 0.97, which is 46% below median its own 10-year median of 1.79. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Soiken Holdings stock overvalued right now?
Based on GuruFocus' analysis, Soiken Holdings (TSE:2385) is currently considered Significantly Overvalued. The stock's GF Value™ is 円111.55, compared to a current price of 円224.00 — trading 100.8% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 0.97, which is 46% below median its 10-year median of 1.79 and 40.9% below the Biotechnology industry median of 1.64. Soiken Holdings' overall GF Score™ is 55/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Soiken Holdings (TSE:2385), the current Cyclically Adjusted PB Ratio is 0.97 as of Aug. 31, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Soiken Holdings (TSE:2385) Overvalued in 2026?

Based on GuruFocus' analysis, Soiken Holdings stock appears to be overvalued. The current stock price of 円224.00 is trading 100.8% above its estimated GF Value™ of 円111.55. GuruFocus considers Soiken Holdings to be Significantly Overvalued.

Key valuation signals for TSE:2385:

  • Cyclically Adjusted PB Ratio: 0.97 (46% below median its 10-year median of 1.79)
  • GF Value™: 円111.55 vs. price of 円224.00 (100.8% above fair value)
  • GF Score™: 55/100 with 2 warning signs
  • Industry Position: 40.9% below the Biotechnology median (#255 of 681)

No single metric tells the full story. See the TSE:2385 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Soiken Holdings Business Description

Address 1-4-2 Shinsenri-Higashimachi, 13th Floor, Senri Life Science Center, Toyonaka, Osaka, JPN, 560-0082
Soiken Holdings Inc operates as a biotechnology company in Japan. It provides clinical testing for pharmaceutical and food manufacturers that develop drugs and health food products based on biomarkers. It is involved in the marketing research and post-marketing surveillance of health supplements.
55GF Score

Get the complete analysis for TSE:2385

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円224.00
Price
円111.55
GF Value