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Chiome BioscienceTSE:4583 38 Cyclically Adjusted PS Ratio is 5.00 as of Jul. 29, 2026, which is 53% below its 10-year median of 10.73. GuruFocus rates TSE:4583 with a GF Score™ of 38/100 and a GF Value™ of 円105.90 (Possible Value Trap). The stock has 2 warning signs investors should review. Among 537 Biotechnology companies, Chiome Bioscience ranks better than 51.58% on this metric.
The historical rank and industry rank for Chiome Bioscience's Cyclically Adjusted PS Ratio or its related term are showing as below:
TSE:4583'
s Cyclically Adjusted PS Ratio Range Over the Past 10 Years
Min: 4.93 Med: 10.73 Max: 20.5
Current: 5
During the past years, Chiome Bioscience's highest Cyclically Adjusted PS Ratio was 20.50. The lowest was 4.93. And the median was 10.73.
TSE:4583's Cyclically Adjusted PS Ratio is ranked better than 51.58% of 537
companies
in the Biotechnology industry
Industry Median: 5.65
vs TSE:4583: 5.00
The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio. The Cyclically Adjusted Revenue per Share is the average of the inflation adjusted revenue per share of a company over the past 10 years.
Chiome Bioscience's adjusted revenue per share data for the three months ended in Dec. 2025 was 円3.988. Add all the adjusted revenue per share for the past 10 years together and divide 10 will get our Cyclically Adjusted Revenue per Share, which is 円13.59 for the trailing ten years ended in Dec. 2025.
Shiller PE for Stocks: The True Measure of Stock Valuation
Chiome Bioscience (TSE:4583) Cyclically Adjusted PS Ratio Explanation
Compared with the regular PS Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PS Ratio smoothed out the fluctuations of revenue during business cycles. Therefore it is more accurate in reflecting the valuation of the company.
If a company has consistent business performance, the Cyclically Adjusted PS Ratio should give similar results to regular PS Ratio.
Chiome Bioscience Cyclically Adjusted PS Ratio Related Terms
Chiome Bioscience Cyclically Adjusted PS Ratio Historical Data
* Premium members only.
The historical data trend for Chiome Bioscience's Cyclically Adjusted PS Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Chiome Bioscience Cyclically Adjusted PS Ratio Chart
TSE:4583 vs VRTX, REGN, RVMD: Cyclically Adjusted PS Ratio Comparison
For the Biotechnology subindustry, Chiome Bioscience's Cyclically Adjusted PS Ratio, along with its competitors' market caps and Cyclically Adjusted PS Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Chiome Bioscience Cyclically Adjusted PS Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Chiome Bioscience's Cyclically Adjusted PS Ratio distribution charts can be found below:
* The bar in red indicates where Chiome Bioscience's Cyclically Adjusted PS Ratio falls into.
Chiome Bioscience Cyclically Adjusted PS Ratio Calculation
Like the Shiller PE Ratio, the Cyclically Adjusted PS Ratio takes the Revenue per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/S calculation. Because it considers this 10-year average, it's often referred to as the CAPS Ratio.
The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio.
Chiome Bioscience's Cyclically Adjusted PS Ratio for today is calculated as
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.
What does a Cyclically Adjusted PS Ratio of 5.00 mean?
Chiome Bioscience (TSE:4583) has a Cyclically Adjusted PS Ratio of 5.00 as of Jul. 29, 2026. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on Chiome Bioscience and its competitors. This is 53% below median its historical median of 10.73. Over the past decade, Chiome Bioscience's Cyclically Adjusted PS Ratio has ranged from 4.93 to 20.50. According to the industry distribution chart, Chiome Bioscience ranks #260 out of 537 companies in the Biotechnology industry, placing it in the top 48.4%.
Is Chiome Bioscience's Cyclically Adjusted PS Ratio too high?
Chiome Bioscience's current Cyclically Adjusted PS Ratio of 5.00 is 53% below median its 10-year median of 10.73. Over the past 10 years, this metric has ranged from a low of 4.93 to a high of 20.50. The Biotechnology industry median Cyclically Adjusted PS Ratio is 5.65. Chiome Bioscience's value of 5.00 is 11.5% below this industry median. Based on the distribution chart, Chiome Bioscience ranks #260 out of 537 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Chiome Bioscience has a GF Score™ of 38/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Chiome Bioscience's Cyclically Adjusted PS Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Chiome Bioscience ranks #260 out of 537 companies for Cyclically Adjusted PS Ratio. This puts Chiome Bioscience in the upper half of its industry. The industry median Cyclically Adjusted PS Ratio is 5.65. Chiome Bioscience's value of 5.00 is 11.5% below this benchmark. Historically, Chiome Bioscience's own Cyclically Adjusted PS Ratio has ranged from 4.93 to 20.50 over the past decade. While the company's 10-year median is 10.73 vs. the industry median of 5.65, Chiome Bioscience has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PS Ratio for a Biotechnology company?
The median Cyclically Adjusted PS Ratio among Biotechnology companies is 5.65, based on 537 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PS Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PS Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Chiome Bioscience's current Cyclically Adjusted PS Ratio of 5.00 is 11.5% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PS Ratio mean?
A high Cyclically Adjusted PS Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on Chiome Bioscience and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PS Ratio is 5.65 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Chiome Bioscience's current Cyclically Adjusted PS Ratio is 5.00, which is 53% below median its own 10-year median of 10.73. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Chiome Bioscience stock overvalued right now?
Based on GuruFocus' analysis, Chiome Bioscience (TSE:4583) is currently considered Possible Value Trap. The stock's GF Value™ is 円105.90, compared to a current price of 円68.00 — trading 35.8% below its estimated fair value. The current Cyclically Adjusted PS Ratio is 5.00, which is 53% below median its 10-year median of 10.73 and 11.5% below the Biotechnology industry median of 5.65. Chiome Bioscience's overall GF Score™ is 38/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PS Ratio calculated?
Cyclically Adjusted PS Ratio is calculated from a company's financial statements. For Chiome Bioscience (TSE:4583), the current Cyclically Adjusted PS Ratio is 5.00 as of Jul. 29, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Chiome Bioscience (TSE:4583) Overvalued in 2026?
Based on GuruFocus' analysis, Chiome Bioscience stock appears to be undervalued.
The current stock price of 円68.00 is trading 35.8% below its estimated GF Value™ of 円105.90.
GuruFocus considers Chiome Bioscience to be Possible Value Trap.
Key valuation signals for TSE:4583:
Cyclically Adjusted PS Ratio: 5.00 (53% below median its 10-year median of 10.73)
GF Value™: 円105.90 vs. price of 円68.00 (35.8% below fair value)
Industry Position: 11.5% below the Biotechnology median (#260 of 537)
No single metric tells the full story. See the TSE:4583 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Chiome Bioscience Inc is engaged in the discovery and development of antibody drugs, focusing on early-stage research and initial clinical trials. The company operates through two reportable segments: the Drug Discovery segment and the Drug Discovery Support segment. The Drug Discovery segment conducts research on antibody creation for diseases with high unmet medical needs and aims to generate revenue through licensing agreements, upfront payments, milestone payments, and royalties. The Drug Discovery Support segment provides services such as antibody production and related support using proprietary antibody technologies, catering to pharmaceutical and diagnostic companies as well as academic institutions.
38GF Score
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