Chiome Bioscience (TSE:4583) EV-to-EBIT: -5.90 (As of Aug. 25, 2026)

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TSE:4583 Chiome Bioscience Inc TSE:4583
52 GF Score
Price 円83.00
GF Value 円88.36
Valuation Fairly Valued
! 2 Warning Signs
View Full Analysis

What is Chiome Bioscience EV-to-EBIT?

Chiome Bioscience TSE:4583 -1.19% 52 EV-to-EBIT is -5.90 as of Aug. 25, 2026. GuruFocus rates TSE:4583 with a GF Score™ of 52/100 and a GF Value™ of 円88.36 (Fairly Valued). The stock has 2 warning signs investors should review. Among 376 Biotechnology companies, Chiome Bioscience ranks worse than 265957.18% on this metric.

EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, Chiome Bioscience's Enterprise Value is 円5,429.0 Mil. Chiome Bioscience's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 was 円-920.7 Mil. Therefore, Chiome Bioscience's EV-to-EBIT for today is -5.90.

The historical rank and industry rank for Chiome Bioscience's EV-to-EBIT or its related term are showing as below:

TSE:4583' s EV-to-EBIT Range Over the Past 10 Years
Min: -16.13   Med: -4.92   Max: -1.3
Current: -5.9

During the past 13 years, the highest EV-to-EBIT of Chiome Bioscience was -1.30. The lowest was -16.13. And the median was -4.92.

TSE:4583's EV-to-EBIT is ranked worse than
100% of 376 companies
in the Biotechnology industry
Industry Median: 16.275 vs TSE:4583: -5.90

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %. Chiome Bioscience's Enterprise Value for the quarter that ended in Jun. 2026 was 円4,929.9 Mil. Chiome Bioscience's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 was 円-920.7 Mil. Chiome Bioscience's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Jun. 2026 was -18.68%.


Chiome Bioscience  (TSE:4583) EV-to-EBIT Explanation

This is a more accurate valuation of companies' operation because it considers the debt and cash on its balance sheet, and non-operating items such as interest payment, tax, and one-time items are not included in the Operating Income.

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %.

Chiome Bioscience's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Jun. 2026 is calculated as:

Earnings Yield (Joel Greenblatt) % (Q: Jun. 2026 ) =EBIT / Enterprise Value (Q: Jun. 2026 )
=-920.671/4929.921
=-18.68 %

Chiome Bioscience's Enterprise Value for the quarter that ended in Jun. 2026 was 円4,929.9 Mil.
Chiome Bioscience's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-920.7 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Chiome Bioscience EV-to-EBIT Related Terms


Chiome Bioscience EV-to-EBIT Historical Data

* Premium members only.

The historical data trend for Chiome Bioscience's EV-to-EBIT can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Chiome Bioscience EV-to-EBIT Chart

Chiome Bioscience Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBIT
Get a 7-Day Free Trial Premium Member Only Premium Member Only -4.33 -5.72 -5.01 -15.99 -6.53

Chiome Bioscience Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
EV-to-EBIT Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -16.63 -10.13 -6.53 -6.81 -5.35

TSE:4583 vs VRTX, REGN, RVMD: EV-to-EBIT Comparison

For the Biotechnology subindustry, Chiome Bioscience's EV-to-EBIT, along with its competitors' market caps and EV-to-EBIT data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Chiome Bioscience EV-to-EBIT vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Chiome Bioscience's EV-to-EBIT distribution charts can be found below:

* The bar in red indicates where Chiome Bioscience's EV-to-EBIT falls into.


TSE:4583
52GF Score
Chiome Bioscience Inc TSE:4583
EV-to-EBIT is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Chiome Bioscience EV-to-EBIT Calculation

Chiome Bioscience's EV-to-EBIT for today is calculated as:

EV-to-EBIT=Enterprise Value (Today)/EBIT (TTM)
=5429.034/-920.671
=-5.90

Chiome Bioscience's current Enterprise Value is 円5,429.0 Mil.
Chiome Bioscience's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-920.7 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBIT →
What does a EV-to-EBIT of -5.90 mean?
Chiome Bioscience (TSE:4583) has a EV-to-EBIT of -5.90 as of Aug. 25, 2026. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Chiome Bioscience and its competitors. According to the industry distribution chart, Chiome Bioscience ranks #999999 out of 376 companies in the Biotechnology industry.
Is Chiome Bioscience's EV-to-EBIT too high?
Chiome Bioscience's current EV-to-EBIT is -5.90. Based on the distribution chart, Chiome Bioscience ranks #999999 out of 376 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Chiome Bioscience has a GF Score™ of 52/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Chiome Bioscience's EV-to-EBIT compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Chiome Bioscience ranks #999999 out of 376 companies for EV-to-EBIT. This places Chiome Bioscience in the lower half of its industry. The industry median EV-to-EBIT is 16.28. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBIT for a Biotechnology company?
The median EV-to-EBIT among Biotechnology companies is 16.28, based on 376 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBIT significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBIT should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBIT mean?
A high EV-to-EBIT can signal that a stock is expensive relative to its fundamentals. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Chiome Bioscience and its competitors. For the Biotechnology industry, the median EV-to-EBIT is 16.28 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Chiome Bioscience's current EV-to-EBIT is -5.90. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Chiome Bioscience stock overvalued right now?
Based on GuruFocus' analysis, Chiome Bioscience (TSE:4583) is currently considered Fairly Valued. The stock's GF Value™ is 円88.36, compared to a current price of 円83.00 — trading 6.1% below its estimated fair value. The current EV-to-EBIT is -5.90. Chiome Bioscience's overall GF Score™ is 52/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBIT calculated?
EV-to-EBIT is calculated from a company's financial statements. For Chiome Bioscience (TSE:4583), the current EV-to-EBIT is -5.90 as of Aug. 25, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Chiome Bioscience (TSE:4583) Overvalued in 2026?

Based on GuruFocus' analysis, Chiome Bioscience stock appears to be undervalued. The current stock price of 円83.00 is trading 6.1% below its estimated GF Value™ of 円88.36. GuruFocus considers Chiome Bioscience to be Fairly Valued.

Key valuation signals for TSE:4583:

  • EV-to-EBIT: -5.90
  • GF Value™: 円88.36 vs. price of 円83.00 (6.1% below fair value)
  • GF Score™: 52/100 with 2 warning signs

No single metric tells the full story. See the TSE:4583 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Chiome Bioscience Business Description

Address 3-12-1 Honmachi, No. 6, Sumitomo Fudosan Nishi Shinjuku Building, Shibuya-ku, Tokyo, JPN, 151-0071
Chiome Bioscience Inc is engaged in the discovery and development of antibody drugs, focusing on early-stage research and initial clinical trials. The company operates through two reportable segments: the Drug Discovery segment and the Drug Discovery Support segment. The Drug Discovery segment conducts research on antibody creation for diseases with high unmet medical needs and aims to generate revenue through licensing agreements, upfront payments, milestone payments, and royalties. The Drug Discovery Support segment provides services such as antibody production and related support using proprietary antibody technologies, catering to pharmaceutical and diagnostic companies as well as academic institutions.
52GF Score

Get the complete analysis for TSE:4583

EV-to-EBIT is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円83.00
Price
円88.36
GF Value