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Opus GeneticsIRD -6.15%24 Debt-to-Equity is -0.03 as of Mar. 2026. GuruFocus rates IRD with a GF Score™ of 24/100 and a GF Value™ of $0.36 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 966 Biotechnology companies, Opus Genetics ranks worse than 103519.57% on this metric.
A high debt to equity ratio generally means that a company has been aggressive in financing its growth with debt. This can result in volatile earnings as a result of the additional interest expense.
The historical rank and industry rank for Opus Genetics's Debt-to-Equity or its related term are showing as below:
IRD'
s Debt-to-Equity Range Over the Past 10 Years
Min: -0.75 Med: 0.02 Max: 0.18
Current: -0.03
During the past 7 years, the highest Debt-to-Equity Ratio of Opus Genetics was 0.18. The lowest was -0.75. And the median was 0.02.
IRD's Debt-to-Equity is not ranked
in the Biotechnology industry.
Industry Median: 0.16
vs IRD: -0.03
Opus Genetics (NAS:IRD) Debt-to-Equity Explanation
Because a company can increase its ROE % by having more financial leverage, it is important to watch the leverage ratio when investing in high ROE % companies.
Opus Genetics Debt-to-Equity Related Terms
Opus Genetics Debt-to-Equity Historical Data
* Premium members only.
The historical data trend for Opus Genetics's Debt-to-Equity can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
IRD vs PALI, VSTM, GALT: Debt-to-Equity Comparison
For the Biotechnology subindustry, Opus Genetics's Debt-to-Equity, along with its competitors' market caps and Debt-to-Equity data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Opus Genetics Debt-to-Equity vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Opus Genetics's Debt-to-Equity distribution charts can be found below:
* The bar in red indicates where Opus Genetics's Debt-to-Equity falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Opus Genetics (IRD) has a Debt-to-Equity of -0.03 as of Mar. 2026. Debt-to-Equity ratio represents the ratio of total debt to total company equity. View historical data on Opus Genetics and its competitors. According to the industry distribution chart, Opus Genetics ranks #999999 out of 966 companies in the Biotechnology industry.
Is Opus Genetics' Debt-to-Equity too high?
Opus Genetics' current Debt-to-Equity is -0.03. Based on the distribution chart, Opus Genetics ranks #999999 out of 966 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Opus Genetics has a GF Score™ of 24/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Opus Genetics' Debt-to-Equity compare to PALI and VSTM?
According to the Biotechnology industry distribution chart, Opus Genetics ranks #999999 out of 966 companies for Debt-to-Equity. This places Opus Genetics in the lower half of its industry. The industry median Debt-to-Equity is 0.16. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Debt-to-Equity for a Biotechnology company?
The median Debt-to-Equity among Biotechnology companies is 0.16, based on 966 companies in the industry. Companies in the top quartile (top 25%) have a Debt-to-Equity significantly above this median, while those in the bottom quartile fall well below. However, Debt-to-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Debt-to-Equity mean?
A high Debt-to-Equity can signal that a stock is expensive relative to its fundamentals. Debt-to-Equity ratio represents the ratio of total debt to total company equity. View historical data on Opus Genetics and its competitors. For the Biotechnology industry, the median Debt-to-Equity is 0.16 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Opus Genetics's current Debt-to-Equity is -0.03. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Opus Genetics stock overvalued right now?
Based on GuruFocus' analysis, Opus Genetics (IRD) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.36, compared to a current price of $3.28 — trading 811.1% above its estimated fair value. The current Debt-to-Equity is -0.03. Opus Genetics' overall GF Score™ is 24/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Debt-to-Equity calculated?
Debt-to-Equity is calculated from a company's financial statements. For Opus Genetics (IRD), the current Debt-to-Equity is -0.03 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Opus Genetics (IRD) Overvalued in 2026?
Based on GuruFocus' analysis, Opus Genetics stock appears to be overvalued.
The current stock price of $3.28 is trading 811.1% above its estimated GF Value™ of $0.36.
GuruFocus considers Opus Genetics to be Significantly Overvalued.
Key valuation signals for IRD:
Debt-to-Equity: -0.03
GF Value™: $0.36 vs. price of $3.28 (811.1% above fair value)
No single metric tells the full story. See the IRD stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Opus Genetics Inc is a clinical-stage ophthalmic biopharmaceutical company developing therapies to treat patients with inherited retinal diseases (IRDs) and therapies to treat patients with other retinal and refractive disorders. The pipeline includes seven adeno-associated virus (AAV)-based programs, led by OPGx-LCA5 for LCA5-related mutations and OPGx-BEST1 for BEST1-related retinal degeneration, with additional candidates targeting RHO, CNGB1, RDH12, NMNAT1, and MERTK. The company operates in one operating segment, which is the business of developing products related to vision performance and health.
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