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Opus GeneticsIRD -6.80%20 Degree of Operating Leverage is -2.21 as of Jun. 2026. GuruFocus rates IRD with a GF Score™ of 20/100 and a GF Value™ of $0.28 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 859 Biotechnology companies, Opus Genetics ranks better than 79.86% on this metric.
Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue.
Opus Genetics's Degree of Operating Leverage for the quarter that ended in Jun. 2026 was -2.21. The higher Degree of Operating Leverage, the higher operating risk the company will take.
The industry rank for Opus Genetics's Degree of Operating Leverage or its related term are showing as below:
IRD's Degree of Operating Leverage is ranked better than 79.86% of 859
companies
in the Biotechnology industry
Industry Median: -0.01
vs IRD: -2.21
Opus Genetics (NAS:IRD) Degree of Operating Leverage Explanation
Degree of Operating Leverage (DOL) is a leverage ratio that measures the sensitivity of a company’s operting income, also referred to as Earnings Before Interest and Taxes (EBIT), to fluctuations in its Revenue. DOL is a method used to quantify a company’s operating risk. This risk is related to the company's structure of variable costs and fixed costs. Since the fixed costs do not allow the company to adjust the operating costs, the operating risk rises with a higher fixed-to-variable costs proportion.
A high Degree of Operating Leverage indicates that the company’s fixed costs exceed its variable costs. By increasing the sales, the company can earn more profits. In addition, the company must be able to maintain relatively high sales to cover all fixed costs.
Be Aware
The use of operating leverage varies across different industries and business sectors, and the application of Degree of Operating Leverage (DOL) should be adjusted accordingly.
Opus Genetics Degree of Operating Leverage Related Terms
Opus Genetics Degree of Operating Leverage Historical Data
* Premium members only.
The historical data trend for Opus Genetics's Degree of Operating Leverage can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
IRD vs OBIO, CYDY, YDES: Degree of Operating Leverage Comparison
For the Biotechnology subindustry, Opus Genetics's Degree of Operating Leverage, along with its competitors' market caps and Degree of Operating Leverage data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Opus Genetics Degree of Operating Leverage vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Opus Genetics's Degree of Operating Leverage distribution charts can be found below:
* The bar in red indicates where Opus Genetics's Degree of Operating Leverage falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
** TTM data of EBIT and Revenue was used to calculate Degree of Operating Leverage.
*** Please be aware that the Degree of Operating Leverage calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.
What does a Degree of Operating Leverage of -2.21 mean?
Opus Genetics (IRD) has a Degree of Operating Leverage of -2.21 as of Jun. 2026. Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue. View historical data for Opus Genetics and its competitors. According to the industry distribution chart, Opus Genetics ranks #173 out of 859 companies in the Biotechnology industry, placing it in the top 20.1%.
Is Opus Genetics' Degree of Operating Leverage too high?
Opus Genetics' current Degree of Operating Leverage is -2.21. Based on the distribution chart, Opus Genetics ranks #173 out of 859 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Opus Genetics has a GF Score™ of 20/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Opus Genetics' Degree of Operating Leverage compare to OBIO and CYDY?
According to the Biotechnology industry distribution chart, Opus Genetics ranks #173 out of 859 companies for Degree of Operating Leverage. This places Opus Genetics in the top 20% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Degree of Operating Leverage for a Biotechnology company?
A good Degree of Operating Leverage depends on the Biotechnology industry context. However, Degree of Operating Leverage should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Degree of Operating Leverage mean?
A high Degree of Operating Leverage can signal that a stock is expensive relative to its fundamentals. Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue. View historical data for Opus Genetics and its competitors. Opus Genetics's current Degree of Operating Leverage is -2.21. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Opus Genetics stock overvalued right now?
Based on GuruFocus' analysis, Opus Genetics (IRD) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.28, compared to a current price of $5.41 — trading 1832.1% above its estimated fair value. The current Degree of Operating Leverage is -2.21. Opus Genetics' overall GF Score™ is 20/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Degree of Operating Leverage calculated?
Degree of Operating Leverage is calculated from a company's financial statements. For Opus Genetics (IRD), the current Degree of Operating Leverage is -2.21 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Opus Genetics (IRD) Overvalued in 2026?
Based on GuruFocus' analysis, Opus Genetics stock appears to be overvalued.
The current stock price of $5.41 is trading 1832.1% above its estimated GF Value™ of $0.28.
GuruFocus considers Opus Genetics to be Significantly Overvalued.
Key valuation signals for IRD:
Degree of Operating Leverage: -2.21
GF Value™: $0.28 vs. price of $5.41 (1832.1% above fair value)
No single metric tells the full story. See the IRD stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Opus Genetics Inc is a clinical-stage ophthalmic biopharmaceutical company developing therapies to treat patients with inherited retinal diseases (IRDs) and therapies to treat patients with other retinal and refractive disorders. The pipeline includes seven adeno-associated virus (AAV)-based programs, led by OPGx-LCA5 for LCA5-related mutations and OPGx-BEST1 for BEST1-related retinal degeneration, with additional candidates targeting RHO, CNGB1, RDH12, NMNAT1, and MERTK. The company operates in one operating segment, which is the business of developing products related to vision performance and health.
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