IRD (Opus Genetics) OCF Margin %: -590.03% (As of Mar. 2026)

What is Opus Genetics OCF Margin %?

Opus Genetics IRD -1.21% 24 OCF Margin % is -590.03% as of Mar. 2026. GuruFocus rates IRD with a GF Score™ of 24/100 and a GF Value™ of $0.37 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 960 Biotechnology companies, Opus Genetics ranks worse than 66.88% on this metric.

OCF Margin % is calculated as Cash Flow from Operations divided by its Revenue. Opus Genetics's Cash Flow from Operations for the three months ended in Mar. 2026 was $-12.73 Mil. Opus Genetics's Revenue for the three months ended in Mar. 2026 was $2.16 Mil. Therefore, Opus Genetics's OCF Margin % for the quarter that ended in Mar. 2026 was -590.03%.

As of today, Opus Genetics's current OCF Yield % is -12.90%.

The historical rank and industry rank for Opus Genetics's OCF Margin % or its related term are showing as below:

IRD' s OCF Margin % Range Over the Past 10 Years
Min: -3288.62 Med: -232.68 Max: 35.92
Current: -325.34

During the past 7 years, the highest OCF Margin % of Opus Genetics was 35.92%. The lowest was -3288.62%. And the median was -232.68%.

IRD's OCF Margin % is ranked worse than
66.88% of 960 companies
in the Biotechnology industry
Industry Median: -68.59 vs IRD: -325.34

Opus Genetics OCF Margin % Related Terms

Opus Genetics OCF Margin % Historical Data

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The historical data trend for Opus Genetics's OCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Opus Genetics OCF Margin % Chart

Opus Genetics Annual Data

Trend

Dec19

Dec20

Dec21

Dec22

Dec23

Dec24

Dec25

OCF Margin %

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-3,288.62

35.92

-5.84

-232.68

-248.33

Opus Genetics Quarterly Data
	Jun21	Sep21	Dec21	Mar22	Jun22	Sep22	Dec22	Mar23	Jun23	Sep23	Dec23	Mar24	Jun24	Sep24	Dec24	Mar25	Jun25	Sep25	Dec25	Mar26
OCF Margin %	Get a 7-Day Free Trial															-205.81	-356.32	-199.97	-254.41	-590.03

IRD vs IFRX, RGNX, LRMR: OCF Margin % Comparison

For the Biotechnology subindustry, Opus Genetics's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Opus Genetics OCF Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Opus Genetics's OCF Margin % distribution charts can be found below:

* The bar in red indicates where Opus Genetics's OCF Margin % falls into.

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Opus Genetics OCF Margin % Calculation

OCF Margin % is the ratio of Cash Flow from Operations divided by net sales or Revenue, usually presented in percent.

Opus Genetics's OCF Margin for the fiscal year that ended in Dec. 2025 is calculated as

OCF Margin	=	Cash Flow from Operations (A: Dec. 2025 )	/	Revenue (A: Dec. 2025 )
	=	-35.253	/	14.196
	=	-248.33 %

Opus Genetics's OCF Margin for the quarter that ended in Mar. 2026 is calculated as

OCF Margin	=	Cash Flow from Operations (Q: Mar. 2026 )	/	Revenue (Q: Mar. 2026 )
	=	-12.727	/	2.157
	=	-590.03 %

Frequently Asked Questions Learn more about OCF Margin % →

What does a OCF Margin % of -590.03% mean?

Opus Genetics (IRD) has a OCF Margin % of -590.03% as of Mar. 2026. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Opus Genetics and its competitors. According to the industry distribution chart, Opus Genetics ranks #642 out of 960 companies in the Biotechnology industry, placing it in the top 66.9%.

Is Opus Genetics' OCF Margin % too high?

Opus Genetics' current OCF Margin % is -590.03%. Based on the distribution chart, Opus Genetics ranks #642 out of 960 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Opus Genetics has a GF Score™ of 24/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.

How does Opus Genetics' OCF Margin % compare to IFRX and RGNX?

According to the Biotechnology industry distribution chart, Opus Genetics ranks #642 out of 960 companies for OCF Margin %. This places Opus Genetics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.

What is a good OCF Margin % for a Biotechnology company?

A good OCF Margin % depends on the Biotechnology industry context. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.

What does a high OCF Margin % mean?

A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Opus Genetics and its competitors. Opus Genetics's current OCF Margin % is -590.03%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.

Is Opus Genetics stock overvalued right now?

Based on GuruFocus' analysis, Opus Genetics (IRD) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.37, compared to a current price of $3.66 — trading 889.2% above its estimated fair value. The current OCF Margin % is -590.03%. Opus Genetics' overall GF Score™ is 24/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.

How is OCF Margin % calculated?

OCF Margin % is calculated from a company's financial statements. For Opus Genetics (IRD), the current OCF Margin % is -590.03% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Opus Genetics (IRD) Overvalued in 2026?

Based on GuruFocus' analysis, Opus Genetics stock appears to be overvalued. The current stock price of $3.66 is trading 889.2% above its estimated GF Value™ of $0.37. GuruFocus considers Opus Genetics to be Significantly Overvalued.

Key valuation signals for IRD:

OCF Margin %: -590.03%
GF Value™: $0.37 vs. price of $3.66 (889.2% above fair value)
GF Score™: 24/100 with 4 warning signs

No single metric tells the full story. See the IRD stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

Opus Genetics Business Description

Industry Healthcare Biotechnology

Comparable Companies IFRX RGNX LRMR GLSI NAUT PBYI PALI NMRA NWBO PROK VRTX REGN XBRU:UCB XBRU:ARGX XKRX:207940 ALNY RVMD ASX:CSL ONC XKRX:068270

Other Exchanges R3X1:Germany

Address 8 Davis Drive, Suite 220, Durham, NC, USA, 27713

Website https://www.opusgtx.com

Opus Genetics Inc is a clinical-stage ophthalmic biopharmaceutical company developing therapies to treat patients with inherited retinal diseases (IRDs) and therapies to treat patients with other retinal and refractive disorders. The pipeline includes seven adeno-associated virus (AAV)-based programs, led by OPGx-LCA5 for LCA5-related mutations and OPGx-BEST1 for BEST1-related retinal degeneration, with additional candidates targeting RHO, CNGB1, RDH12, NMNAT1, and MERTK. The company operates in one operating segment, which is the business of developing products related to vision performance and health.

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$3.66

Price

$0.37

GF Value

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