PRPO (Precipio) E10: $-1,029.94 (As of Mar. 2026)

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Director of Data and Quant Analytics at GuruFocus
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Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

PRPO Precipio Inc PRPO
53 GF Score
Price $22.35
GF Value $10.74
Valuation Significantly Overvalued
! 2 Warning Signs
View Full Analysis

What is Precipio E10?

Precipio PRPO -1.11% 53 E10 is $-1,029.94 as of Mar. 2026. GuruFocus rates PRPO with a GF Score™ of 53/100 and a GF Value™ of $10.74 (Significantly Overvalued). The stock has 2 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Precipio's adjusted earnings per share data for the three months ended in Mar. 2026 was $-0.810. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $-1,029.94 for the trailing ten years ended in Mar. 2026.

During the past 3 years, the average E10 Growth Rate was 48.60% per year. During the past 5 years, the average E10 Growth Rate was 33.40% per year. During the past 10 years, the average E10 Growth Rate was 15.70% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of Precipio was 48.60% per year. The lowest was -0.70% per year. And the median was 13.75% per year.

As of today (2026-08-11), Precipio's current stock price is $22.35. Precipio's E10 for the quarter that ended in Mar. 2026 was $-1,029.94. Precipio's Shiller PE Ratio of today is .


Precipio  (NAS:PRPO) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Precipio E10 Related Terms


Precipio E10 Historical Data

* Premium members only.

The historical data trend for Precipio's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Precipio E10 Chart

Precipio Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only -10,153.05 -9,061.28 -6,677.68 -4,495.10 -1,231.10

Precipio Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -4,116.07 -3,786.66 -3,137.26 -1,231.10 -1,029.94

PRPO vs IDXG, ADVB, BIOQ: E10 Comparison

For the Diagnostics & Research subindustry, Precipio's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Precipio Shiller PE Ratio vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Precipio's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Precipio's Shiller PE Ratio falls into.


PRPO
53GF Score
Precipio Inc PRPO
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Precipio E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Precipio's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=-0.81/330.2130*330.2130
=-0.810

Current CPI (Mar. 2026) = 330.2130.

Precipio Quarterly Data

per share eps CPI Adj_EPS
201606 -308.998 241.018 -423.351
201609 -344.998 241.428 -471.871
201612 -662.997 241.432 -906.799
201703 -506.997 243.801 -686.695
201706 -4,604.977 244.955 -6,207.766
201709 -407.998 246.819 -545.850
201712 -394.080 246.524 -527.861
201803 -142.000 249.554 -187.896
201806 -45.800 251.989 -60.018
201809 -49.800 252.439 -65.143
201812 -70.400 251.233 -92.532
201903 -9.600 254.202 -12.471
201906 -21.000 256.143 -27.073
201909 -6.200 256.759 -7.974
201912 -9.600 256.974 -12.336
202003 -15.600 258.115 -19.957
202006 -4.000 257.797 -5.124
202009 -4.200 260.280 -5.328
202012 -2.127 260.474 -2.696
202103 -1.600 264.877 -1.995
202106 -2.800 271.696 -3.403
202109 -1.600 274.310 -1.926
202112 -1.800 278.802 -2.132
202203 -4.000 287.504 -4.594
202206 -1.800 296.311 -2.006
202209 -2.790 296.808 -3.104
202212 -2.010 296.797 -2.236
202303 -2.610 301.836 -2.855
202306 -1.880 305.109 -2.035
202309 -1.040 307.789 -1.116
202312 0.880 306.746 0.947
202403 -1.460 312.332 -1.544
202406 -0.830 314.175 -0.872
202409 -0.420 315.301 -0.440
202412 -0.240 315.605 -0.251
202503 -0.590 319.799 -0.609
202506 0.050 322.561 0.051
202509 -0.050 324.800 -0.051
202512 0.340 324.054 0.346
202603 -0.810 330.213 -0.810

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $-1,029.94 mean?
Precipio (PRPO) has a E10 of $-1,029.94 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Precipio and its competitors.
Is Precipio's E10 too high?
Precipio's current E10 is $-1,029.94. Overall, Precipio has a GF Score™ of 53/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Precipio's E10 compare to IDXG and ADVB?
Precipio's E10 of $-1,029.94 can be compared against companies in the Medical Diagnostics & Research industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Medical Diagnostics & Research company?
A good E10 depends on the Medical Diagnostics & Research industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Precipio and its competitors. Precipio's current E10 is $-1,029.94. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Precipio stock overvalued right now?
Based on GuruFocus' analysis, Precipio (PRPO) is currently considered Significantly Overvalued. The stock's GF Value™ is $10.74, compared to a current price of $22.35 — trading 108.1% above its estimated fair value. The current E10 is $-1,029.94. Precipio's overall GF Score™ is 53/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Precipio (PRPO), the current E10 is $-1,029.94 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Precipio (PRPO) Overvalued in 2026?

Based on GuruFocus' analysis, Precipio stock appears to be overvalued. The current stock price of $22.35 is trading 108.1% above its estimated GF Value™ of $10.74. GuruFocus considers Precipio to be Significantly Overvalued.

Key valuation signals for PRPO:

  • E10: $-1,029.94
  • GF Value™: $10.74 vs. price of $22.35 (108.1% above fair value)
  • GF Score™: 53/100 with 2 warning signs

No single metric tells the full story. See the PRPO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Precipio Business Description

Address 4 Science Park, 3rd Floor, New Haven, CT, USA, 06511
Precipio Inc is a healthcare biotechnology company focused on cancer diagnostics. Its objective is to enhance diagnostic accuracy & accessibility while building a sustainable business model that supports ongoing innovation. The company operates Clinical Laboratory Improvement Amendments laboratories in both New Haven, Connecticut, & Omaha, Nebraska, providing essential blood cancer diagnostics to office-based oncologists in many states nationwide. The company operates in a single segment, which includes two divisions: the Pathology Services Division & the Products Division. The Pathology Services provides specialized cancer diagnostic testing services. The pathology services division specializes in diagnostic testing focused mainly on hematologic cancers.
53GF Score

Get the complete analysis for PRPO

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$22.35
Price
$10.74
GF Value