SymBio Pharmaceuticals (TSE:4582) E10: 円0.00 (As of Jun. 2026)

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TSE:4582 SymBio Pharmaceuticals Ltd TSE:4582
27 GF Score
Price 円64.00
GF Value 円43.47
Valuation Significantly Overvalued
! 4 Warning Signs
View Full Analysis

What is SymBio Pharmaceuticals E10?

SymBio Pharmaceuticals TSE:4582 +1.59% 27 E10 is 円0.00 as of Jun. 2026. GuruFocus rates TSE:4582 with a GF Score™ of 27/100 and a GF Value™ of 円43.47 (Significantly Overvalued). The stock has 4 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

SymBio Pharmaceuticals's adjusted earnings per share data for the three months ended in Jun. 2026 was 円0.000. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is 円0.00 for the trailing ten years ended in Jun. 2026.

During the past 3 years, the average E10 Growth Rate was 9.80% per year. During the past 5 years, the average E10 Growth Rate was 32.50% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of SymBio Pharmaceuticals was 53.90% per year. The lowest was 9.80% per year. And the median was 32.55% per year.

As of today (2026-08-29), SymBio Pharmaceuticals's current stock price is 円64.00. SymBio Pharmaceuticals's E10 for the quarter that ended in Jun. 2026 was 円0.00. SymBio Pharmaceuticals's Shiller PE Ratio of today is .


SymBio Pharmaceuticals  (TSE:4582) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


SymBio Pharmaceuticals E10 Related Terms


SymBio Pharmaceuticals E10 Historical Data

* Premium members only.

The historical data trend for SymBio Pharmaceuticals's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

SymBio Pharmaceuticals E10 Chart

SymBio Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only -227.61 -181.85 -160.01 -157.97 -133.48

SymBio Pharmaceuticals Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -154.84 -152.33 -133.48 -127.44 0.00

TSE:4582 vs ZTS: E10 Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, SymBio Pharmaceuticals's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


SymBio Pharmaceuticals Shiller PE Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, SymBio Pharmaceuticals's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where SymBio Pharmaceuticals's Shiller PE Ratio falls into.


TSE:4582
27GF Score
SymBio Pharmaceuticals Ltd TSE:4582
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

SymBio Pharmaceuticals E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, SymBio Pharmaceuticals's adjusted earnings per share data for the three months ended in Jun. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=0/113.6000*113.6000
=0.000

Current CPI (Jun. 2026) = 113.6000.

SymBio Pharmaceuticals Quarterly Data

per share eps CPI Adj_EPS
201609 -70.720 98.000 -81.977
201612 -34.166 98.400 -39.444
201703 -48.480 98.100 -56.140
201706 -55.880 98.500 -64.446
201709 -186.200 98.800 -214.092
201712 -31.959 99.400 -36.525
201803 -53.120 99.200 -60.831
201806 -42.030 99.200 -48.131
201809 -30.080 99.900 -34.205
201812 -40.310 99.700 -45.930
201903 -29.920 99.700 -34.091
201906 -65.660 99.800 -74.739
201909 -65.750 100.100 -74.617
201912 -27.852 100.500 -31.482
202003 -35.840 100.300 -40.592
202006 -26.630 99.900 -30.282
202009 -23.008 99.900 -26.163
202012 -39.540 99.300 -45.234
202103 -5.490 99.900 -6.243
202106 0.107 99.500 0.122
202109 13.807 100.100 15.669
202112 43.960 100.100 49.889
202203 4.180 101.100 4.697
202206 24.140 101.800 26.938
202209 11.110 103.100 12.241
202212 -9.800 104.100 -10.694
202303 0.110 104.400 0.120
202306 -2.130 105.200 -2.300
202309 -17.870 106.200 -19.115
202312 -29.300 106.800 -31.166
202403 -18.030 107.200 -19.106
202406 -16.720 108.200 -17.554
202409 -28.680 108.900 -29.918
202412 -21.570 110.700 -22.135
202503 -27.950 111.100 -28.579
202506 -21.497 111.700 -21.863
202509 -24.536 112.000 -24.887
202512 -21.660 113.000 -21.775
202603 -35.890 112.700 -36.177
202606 0.000 113.600 0.000

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of 円0.00 mean?
SymBio Pharmaceuticals (TSE:4582) has a E10 of 円0.00 as of Jun. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on SymBio Pharmaceuticals and its competitors.
Is SymBio Pharmaceuticals' E10 too high?
SymBio Pharmaceuticals' current E10 is 円0.00. Overall, SymBio Pharmaceuticals has a GF Score™ of 27/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does SymBio Pharmaceuticals' E10 compare to ZTS?
SymBio Pharmaceuticals' E10 of 円0.00 can be compared against companies in the Drug Manufacturers industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Drug Manufacturers company?
A good E10 depends on the Drug Manufacturers industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on SymBio Pharmaceuticals and its competitors. SymBio Pharmaceuticals's current E10 is 円0.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is SymBio Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, SymBio Pharmaceuticals (TSE:4582) is currently considered Significantly Overvalued. The stock's GF Value™ is 円43.47, compared to a current price of 円64.00 — trading 47.2% above its estimated fair value. The current E10 is 円0.00. SymBio Pharmaceuticals' overall GF Score™ is 27/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For SymBio Pharmaceuticals (TSE:4582), the current E10 is 円0.00 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is SymBio Pharmaceuticals (TSE:4582) Overvalued in 2026?

Based on GuruFocus' analysis, SymBio Pharmaceuticals stock appears to be overvalued. The current stock price of 円64.00 is trading 47.2% above its estimated GF Value™ of 円43.47. GuruFocus considers SymBio Pharmaceuticals to be Significantly Overvalued.

Key valuation signals for TSE:4582:

  • E10: 円0.00
  • GF Value™: 円43.47 vs. price of 円64.00 (47.2% above fair value)
  • GF Score™: 27/100 with 4 warning signs

No single metric tells the full story. See the TSE:4582 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


SymBio Pharmaceuticals Business Description

Address 1-28 Toranomon 4-chome, 7th Floor, Toranomon Towers Office, Minato-ku, Tokyo, JPN, 105-0001
SymBio Pharmaceuticals Ltd is a biopharmaceutical company engaged in development of new drugs with a primary focus on the treatment of rare diseases, mainly in the areas of oncology, hematology and multiple viral infections, and conduct integrated business activities that encompass search for new drug candidates, development, manufacturing, and sales.
27GF Score

Get the complete analysis for TSE:4582

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円64.00
Price
円43.47
GF Value