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SymBio PharmaceuticalsTSE:4582 36 3-Year ROIIC % is 309.06 as of Dec. 2025, which is 1138% above its 10-year median of 24.97. GuruFocus rates TSE:4582 with a GF Score™ of 36/100 and a GF Value™ of 円60.41 (Modestly Overvalued). The stock has 6 warning signs investors should review. Among 948 Drug Manufacturers companies, SymBio Pharmaceuticals ranks better than 96.1% on this metric.
3-Year Return on Invested Incremental Capital (3-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 3-year.
SymBio Pharmaceuticals's 3-Year ROIIC % for the quarter that ended in Dec. 2025 was 309.06%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
The industry rank for SymBio Pharmaceuticals's 3-Year ROIIC % or its related term are showing as below:
TSE:4582's 3-Year ROIIC % is ranked better than 96.1% of 948
companies
in the Drug Manufacturers industry
Industry Median: 3.675
vs TSE:4582: 309.06
Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.
High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
Be Aware
It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.
SymBio Pharmaceuticals 3-Year ROIIC % Related Terms
SymBio Pharmaceuticals 3-Year ROIIC % Historical Data
* Premium members only.
The historical data trend for SymBio Pharmaceuticals's 3-Year ROIIC % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Drug Manufacturers - Specialty & Generic subindustry, SymBio Pharmaceuticals's 3-Year ROIIC %, along with its competitors' market caps and 3-Year ROIIC % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
SymBio Pharmaceuticals 3-Year ROIIC % vs Drug Manufacturers Industry
For the Drug Manufacturers industry and Healthcare sector, SymBio Pharmaceuticals's 3-Year ROIIC % distribution charts can be found below:
* The bar in red indicates where SymBio Pharmaceuticals's 3-Year ROIIC % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
** Annual data of NOPAT and Invested Capital was used to calculate 3-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.
SymBio Pharmaceuticals (TSE:4582) has a 3-Year ROIIC % of 309.06 as of Dec. 2025. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on SymBio Pharmaceuticals and its competitors. This is 1138% above median its historical median of 24.97. According to the industry distribution chart, SymBio Pharmaceuticals ranks #37 out of 948 companies in the Drug Manufacturers industry, placing it in the top 3.9%.
Is SymBio Pharmaceuticals' 3-Year ROIIC % too high?
SymBio Pharmaceuticals' current 3-Year ROIIC % of 309.06 is 1138% above median its 10-year median of 24.97. The Drug Manufacturers industry median 3-Year ROIIC % is 3.68. SymBio Pharmaceuticals' value of 309.06 is 8309.8% above this industry median. Based on the distribution chart, SymBio Pharmaceuticals ranks #37 out of 948 companies in the Drug Manufacturers industry, which is in the top quartile — a strong position relative to peers. Overall, SymBio Pharmaceuticals has a GF Score™ of 36/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does SymBio Pharmaceuticals' 3-Year ROIIC % compare to ZTS?
According to the Drug Manufacturers industry distribution chart, SymBio Pharmaceuticals ranks #37 out of 948 companies for 3-Year ROIIC %. This places SymBio Pharmaceuticals in the top 4% of its industry — outperforming the majority of peers. The industry median 3-Year ROIIC % is 3.68. SymBio Pharmaceuticals' value of 309.06 is 8309.8% above this benchmark. While the company's 10-year median is 24.97 vs. the industry median of 3.68, SymBio Pharmaceuticals has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year ROIIC % for a Drug Manufacturers company?
The median 3-Year ROIIC % among Drug Manufacturers companies is 3.68, based on 948 companies in the industry. Companies in the top quartile (top 25%) have a 3-Year ROIIC % significantly above this median, while those in the bottom quartile fall well below. However, 3-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. SymBio Pharmaceuticals's current 3-Year ROIIC % of 309.06 is 8309.8% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year ROIIC % mean?
A high 3-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on SymBio Pharmaceuticals and its competitors. For the Drug Manufacturers industry, the median 3-Year ROIIC % is 3.68 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. SymBio Pharmaceuticals's current 3-Year ROIIC % is 309.06, which is 1138% above median its own 10-year median of 24.97. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is SymBio Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, SymBio Pharmaceuticals (TSE:4582) is currently considered Modestly Overvalued. The stock's GF Value™ is 円60.41, compared to a current price of 円70.00 — trading 15.9% above its estimated fair value. The current 3-Year ROIIC % is 309.06, which is 1138% above median its 10-year median of 24.97 and 8309.8% above the Drug Manufacturers industry median of 3.68. SymBio Pharmaceuticals' overall GF Score™ is 36/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year ROIIC % calculated?
3-Year ROIIC % is calculated from a company's financial statements. For SymBio Pharmaceuticals (TSE:4582), the current 3-Year ROIIC % is 309.06 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is SymBio Pharmaceuticals (TSE:4582) Overvalued in 2026?
Based on GuruFocus' analysis, SymBio Pharmaceuticals stock appears to be overvalued.
The current stock price of 円70.00 is trading 15.9% above its estimated GF Value™ of 円60.41.
GuruFocus considers SymBio Pharmaceuticals to be Modestly Overvalued.
Key valuation signals for TSE:4582:
3-Year ROIIC %: 309.06 (1138% above median its 10-year median of 24.97)
GF Value™: 円60.41 vs. price of 円70.00 (15.9% above fair value)
Industry Position: 8309.8% above the Drug Manufacturers median (#37 of 948)
No single metric tells the full story. See the TSE:4582 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
SymBio Pharmaceuticals Ltd is a biopharmaceutical company engaged in development of new drugs with a primary focus on the treatment of rare diseases, mainly in the areas of oncology, hematology and multiple viral infections, and conduct integrated business activities that encompass search for new drug candidates, development, manufacturing, and sales.
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