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Amylyx PharmaceuticalsAMLX +5.17%33 Earnings Yield (Joel Greenblatt) % is -12.55% as of Mar. 2026. GuruFocus rates AMLX with a GF Score™ of 33/100. The stock has 3 warning signs investors should review. Among 1,010 Drug Manufacturers companies, Amylyx Pharmaceuticals ranks worse than 83.86% on this metric.
Amylyx Pharmaceuticals's Enterprise Value for the quarter that ended in Mar. 2026 was $1,269.12 Mil.
Amylyx Pharmaceuticals's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-159.27 Mil. Amylyx Pharmaceuticals's Earnings Yield (Joel Greenblatt) for the quarter that ended in Mar. 2026 was -12.55%.
The historical rank and industry rank for Amylyx Pharmaceuticals's Earnings Yield (Joel Greenblatt) % or its related term are showing as below:
AMLX'
s Earnings Yield (Joel Greenblatt) % Range Over the Past 10 Years
Min: -2153.49 Med: -11.51 Max: 1099.3
Current: -7.84
During the past 7 years, the highest Earnings Yield (Joel Greenblatt) of Amylyx Pharmaceuticals was 1099.30%. The lowest was -2153.49%. And the median was -11.51%.
AMLX's Earnings Yield (Joel Greenblatt) % is ranked worse than 83.86% of 1010
companies
in the Drug Manufacturers industry
Industry Median: 3.36
vs AMLX: -7.84
Joel Greenblatt's definition of earnings yield has the same problems the regular earnings yield does. It does not consider the growth of the company. It only looks at one-year's business operation. For cyclical companies, the earnings yield is usually highest at the peak of the business cycle. But these earnings are rarely sustainable.
A better indicator of the attractiveness of an investment which takes growth into account is the Forward Rate of Return (Yacktman) %. Amylyx Pharmaceuticals's Forward Rate of Return (Yacktman) % for the quarter that ended in Mar. 2026 was 0.00%. The Forward Rate of Return uses the normalized Free Cash Flow of the past five years, and considers growth. The forward rate of return can be thought of as the return that investors buying the stock today can expect from it in the future.
Joel Greenblatt defines the earnings yield using the above equation because it more accurately reflects the company's profitability relative to its stock price. Items like interest payment and tax etc. are not directly related to the company's operational profitability.
Enterprise Value instead of market cap (share price) is used in the calculation because it is the real price stock and bond investors together pay for the company.
Be Aware
Joel Greenblatt's definition of earnings yield has the same problems the regular earnings yield does. It does not consider the growth of the company. It only looks at one-year's business operation. For cyclical companies, the earnings yield is usually highest at the peak of the business cycle. But these earnings are rarely sustainable.
Amylyx Pharmaceuticals Earnings Yield (Joel Greenblatt) % Related Terms
Amylyx Pharmaceuticals Earnings Yield (Joel Greenblatt) % Historical Data
* Premium members only.
The historical data trend for Amylyx Pharmaceuticals's Earnings Yield (Joel Greenblatt) % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Drug Manufacturers - Specialty & Generic subindustry, Amylyx Pharmaceuticals's Earnings Yield (Joel Greenblatt) %, along with its competitors' market caps and Earnings Yield (Joel Greenblatt) % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Amylyx Pharmaceuticals Earnings Yield (Joel Greenblatt) % vs Drug Manufacturers Industry
For the Drug Manufacturers industry and Healthcare sector, Amylyx Pharmaceuticals's Earnings Yield (Joel Greenblatt) % distribution charts can be found below:
* The bar in red indicates where Amylyx Pharmaceuticals's Earnings Yield (Joel Greenblatt) % falls into.
In his book, The Little That Beat the Market, hedge fund manager Joel Greenblatt defines Earnings Yield as operating income divided by enterprise value.
Amylyx Pharmaceuticalss Earnings Yield (Joel Greenblatt) for the fiscal year that ended in Dec. 2025 is calculated as
Amylyx Pharmaceuticals's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-159.27 Mil.
What does a Earnings Yield (Joel Greenblatt) % of -12.55% mean?
Amylyx Pharmaceuticals (AMLX) has a Earnings Yield (Joel Greenblatt) % of -12.55% as of Mar. 2026. Joel Greenblatt's earnings yield equals the ratio of earnings before interest and taxes to enterprise value. View historical data on Amylyx Pharmaceuticals and its competitors. According to the industry distribution chart, Amylyx Pharmaceuticals ranks #847 out of 1010 companies in the Drug Manufacturers industry, placing it in the top 83.9%.
Is Amylyx Pharmaceuticals' Earnings Yield (Joel Greenblatt) % too high?
Amylyx Pharmaceuticals' current Earnings Yield (Joel Greenblatt) % is -12.55%. Based on the distribution chart, Amylyx Pharmaceuticals ranks #847 out of 1010 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, Amylyx Pharmaceuticals has a GF Score™ of 33/100, reflecting its overall financial health beyond just this single metric.
How does Amylyx Pharmaceuticals' Earnings Yield (Joel Greenblatt) % compare to ANIP and PBH?
According to the Drug Manufacturers industry distribution chart, Amylyx Pharmaceuticals ranks #847 out of 1010 companies for Earnings Yield (Joel Greenblatt) %. This places Amylyx Pharmaceuticals in the lower half of its industry. The industry median Earnings Yield (Joel Greenblatt) % is 3.36. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Earnings Yield (Joel Greenblatt) % for a Drug Manufacturers company?
The median Earnings Yield (Joel Greenblatt) % among Drug Manufacturers companies is 3.36, based on 1,010 companies in the industry. Companies in the top quartile (top 25%) have a Earnings Yield (Joel Greenblatt) % significantly above this median, while those in the bottom quartile fall well below. However, Earnings Yield (Joel Greenblatt) % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Earnings Yield (Joel Greenblatt) % mean?
A high Earnings Yield (Joel Greenblatt) % can signal that a stock is expensive relative to its fundamentals. Joel Greenblatt's earnings yield equals the ratio of earnings before interest and taxes to enterprise value. View historical data on Amylyx Pharmaceuticals and its competitors. For the Drug Manufacturers industry, the median Earnings Yield (Joel Greenblatt) % is 3.36 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Amylyx Pharmaceuticals's current Earnings Yield (Joel Greenblatt) % is -12.55%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Amylyx Pharmaceuticals stock overvalued right now?
Amylyx Pharmaceuticals (AMLX) has a current Earnings Yield (Joel Greenblatt) % of -12.55%. The current Earnings Yield (Joel Greenblatt) % is -12.55%. Amylyx Pharmaceuticals' overall GF Score™ is 33/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Earnings Yield (Joel Greenblatt) % calculated?
Earnings Yield (Joel Greenblatt) % is calculated from a company's financial statements. For Amylyx Pharmaceuticals (AMLX), the current Earnings Yield (Joel Greenblatt) % is -12.55% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Amylyx Pharmaceuticals Inc is a clinical-stage pharmaceutical company focused on developing novel therapies for communities with high unmet medical needs. The company has preclinical and clinical development programs in endocrine conditions and neurodegenerative diseases. Its pipeline includes investigational therapies matched with diseases based on mechanistic rationale, clinical outcomes, biomarkers, and preclinical data. The company is currently developing avexitide for Post-Bariatric Hypoglycemia, AMX0035 for Wolfram Syndrome, AMX0114 for Amyotrophic Lateral Sclerosis, and AMX0318 for Post-Bariatric Hypoglycemia and other rare diseases.
33GF Score
Get the complete analysis for AMLX
Earnings Yield (Joel Greenblatt) % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
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