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Amylyx PharmaceuticalsAMLX -5.70%33 EV-to-OCF is -18.15 as of Aug. 09, 2026. GuruFocus rates AMLX with a GF Score™ of 33/100. The stock has 2 warning signs investors should review. Among 1,006 Drug Manufacturers companies, Amylyx Pharmaceuticals ranks better than 87.08% on this metric.
EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Amylyx Pharmaceuticals's Enterprise Value is $2,297.17 Mil.
Amylyx Pharmaceuticals's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 was $-126.58 Mil. Therefore, Amylyx Pharmaceuticals's EV-to-OCF for today is -18.15.
The historical rank and industry rank for Amylyx Pharmaceuticals's EV-to-OCF or its related term are showing as below:
AMLX'
s EV-to-OCF Range Over the Past 10 Years
Min: -18.22 Med: -6.74 Max: 78.35
Current: -18.15
During the past 7 years, the highest EV-to-OCF of Amylyx Pharmaceuticals was 78.35. The lowest was -18.22. And the median was -6.74.
AMLX's EV-to-OCF is ranked better than 87.08% of 1006
companies
in the Drug Manufacturers industry
Industry Median: 11.06
vs AMLX: -18.15
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Amylyx Pharmaceuticals's PE Ratio (TTM) for today is calculated as:
Amylyx Pharmaceuticals's share price for today is $22.82.
Amylyx Pharmaceuticals's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-1.430.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Drug Manufacturers - Specialty & Generic subindustry, Amylyx Pharmaceuticals's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Amylyx Pharmaceuticals EV-to-OCF vs Drug Manufacturers Industry
For the Drug Manufacturers industry and Healthcare sector, Amylyx Pharmaceuticals's EV-to-OCF distribution charts can be found below:
* The bar in red indicates where Amylyx Pharmaceuticals's EV-to-OCF falls into.
Amylyx Pharmaceuticals's current Enterprise Value is $2,297.17 Mil.
Amylyx Pharmaceuticals's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-126.58 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Amylyx Pharmaceuticals (AMLX) has a EV-to-OCF of -18.15 as of Aug. 09, 2026. According to the industry distribution chart, Amylyx Pharmaceuticals ranks #130 out of 1006 companies in the Drug Manufacturers industry, placing it in the top 12.9%.
Is Amylyx Pharmaceuticals' EV-to-OCF too high?
Amylyx Pharmaceuticals' current EV-to-OCF is -18.15. Based on the distribution chart, Amylyx Pharmaceuticals ranks #130 out of 1006 companies in the Drug Manufacturers industry, which is in the top quartile — a strong position relative to peers. Overall, Amylyx Pharmaceuticals has a GF Score™ of 33/100, reflecting its overall financial health beyond just this single metric.
How does Amylyx Pharmaceuticals' EV-to-OCF compare to ANIP and PBH?
According to the Drug Manufacturers industry distribution chart, Amylyx Pharmaceuticals ranks #130 out of 1006 companies for EV-to-OCF. This places Amylyx Pharmaceuticals in the top 13% of its industry — outperforming the majority of peers. The industry median EV-to-OCF is 11.06. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Drug Manufacturers company?
The median EV-to-OCF among Drug Manufacturers companies is 11.06, based on 1,006 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-OCF significantly above this median, while those in the bottom quartile fall well below. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. For the Drug Manufacturers industry, the median EV-to-OCF is 11.06 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Amylyx Pharmaceuticals's current EV-to-OCF is -18.15. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Amylyx Pharmaceuticals stock overvalued right now?
Amylyx Pharmaceuticals (AMLX) has a current EV-to-OCF of -18.15. The current EV-to-OCF is -18.15. Amylyx Pharmaceuticals' overall GF Score™ is 33/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Amylyx Pharmaceuticals (AMLX), the current EV-to-OCF is -18.15 as of Aug. 09, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Amylyx Pharmaceuticals Inc is a clinical-stage pharmaceutical company focused on developing novel therapies for communities with high unmet medical needs. The company has preclinical and clinical development programs in endocrine conditions and neurodegenerative diseases. Its pipeline includes investigational therapies matched with diseases based on mechanistic rationale, clinical outcomes, biomarkers, and preclinical data. The company is currently developing avexitide for Post-Bariatric Hypoglycemia, AMX0035 for Wolfram Syndrome, AMX0114 for Amyotrophic Lateral Sclerosis, and AMX0318 for Post-Bariatric Hypoglycemia and other rare diseases.
33GF Score
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