AMLX (Amylyx Pharmaceuticals) OCF Yield %: -6.09 (As of Jun. 26, 2026)


AMLX Amylyx Pharmaceuticals Inc AMLX
33 GF Score
Price $17.79
! 3 Warning Signs
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What is Amylyx Pharmaceuticals OCF Yield %?

Amylyx Pharmaceuticals AMLX +2.01% 33 OCF Yield % is -6.09 as of Jun. 26, 2026. GuruFocus rates AMLX with a GF Score™ of 33/100. The stock has 3 warning signs investors should review. Among 1,005 Drug Manufacturers companies, Amylyx Pharmaceuticals ranks worse than 82.39% on this metric.

OCF Yield % is calculated as Cash Flow from Operations divided by Market Capitalization. It is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

As of today, Amylyx Pharmaceuticals's Trailing 12-Month Cash Flow from Operations is $-120.40 Mil, and Market Cap is $1,978.01 Mil. Therefore, Amylyx Pharmaceuticals's OCF Yield % for today is -6.09%.

The historical rank and industry rank for Amylyx Pharmaceuticals's OCF Yield % or its related term are showing as below:

AMLX' s OCF Yield % Range Over the Past 10 Years
Min: -74.51   Med: -10.53   Max: 14.83
Current: -6.09


During the past 7 years, the highest OCF Yield % of Amylyx Pharmaceuticals was 14.83%. The lowest was -74.51%. And the median was -10.53%.

AMLX's OCF Yield % is ranked worse than
82.39% of 1005 companies
in the Drug Manufacturers industry
Industry Median: 3.61 vs AMLX: -6.09

Amylyx Pharmaceuticals's OCF Margin % for the quarter that ended in Mar. 2026 was %.


Amylyx Pharmaceuticals OCF Yield % Explanation

Similar to Earnings Yield %, OCF Yield % is financial solvency ratio. A lower ratio suggests a less attractive investment, indicating that investors might not receive substantial returns in proportion to their investment. Conversely, a high operating cash flow yield signals that a company generates sufficient cash to comfortably meet its debts, obligations, and dividend payments, making it a promising investment choice.


Amylyx Pharmaceuticals OCF Yield % Related Terms


Amylyx Pharmaceuticals OCF Yield % Historical Data

* Premium members only.

The historical data trend for Amylyx Pharmaceuticals's OCF Yield % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Amylyx Pharmaceuticals OCF Yield % Chart

Amylyx Pharmaceuticals Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
OCF Yield %
Get a 7-Day Free Trial 0.00 -7.32 1.20 -64.62 -9.29

Amylyx Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
OCF Yield % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -50.51 -17.67 -8.14 -8.41 -9.56

AMLX vs PRGO, ANIP, HROW: OCF Yield % Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Amylyx Pharmaceuticals's OCF Yield %, along with its competitors' market caps and OCF Yield % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Amylyx Pharmaceuticals OCF Yield % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Amylyx Pharmaceuticals's OCF Yield % distribution charts can be found below:

* The bar in red indicates where Amylyx Pharmaceuticals's OCF Yield % falls into.


AMLX
33GF Score
Amylyx Pharmaceuticals Inc AMLX
OCF Yield % is just one metric. See GF Score™, valuation, warning signs, and more.
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Amylyx Pharmaceuticals OCF Yield % Calculation

OCF Yield % is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

Amylyx Pharmaceuticals's OCF Yield % for the fiscal year that ended in Dec. 2025 is calculated as

OCF Yield %=Cash Flow from Operations / Market Cap
=-123.343 / 1327.4108
=-9.29%

Amylyx Pharmaceuticals's annualized OCF Yield % for the quarter that ended in Mar. 2026 is calculated as

OCF Yield %=Cash Flow from Operations * Annualized Factor / Market Cap
=-36.882 * 4 / 1543.2614
=-9.56%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Yield % →
What does a OCF Yield % of -6.09 mean?
Amylyx Pharmaceuticals (AMLX) has a OCF Yield % of -6.09 as of Jun. 26, 2026. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Amylyx Pharmaceuticals and its competitors. According to the industry distribution chart, Amylyx Pharmaceuticals ranks #828 out of 1005 companies in the Drug Manufacturers industry, placing it in the top 82.4%.
Is Amylyx Pharmaceuticals' OCF Yield % too high?
Amylyx Pharmaceuticals' current OCF Yield % is -6.09. Based on the distribution chart, Amylyx Pharmaceuticals ranks #828 out of 1005 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, Amylyx Pharmaceuticals has a GF Score™ of 33/100, reflecting its overall financial health beyond just this single metric.
How does Amylyx Pharmaceuticals' OCF Yield % compare to PRGO and ANIP?
According to the Drug Manufacturers industry distribution chart, Amylyx Pharmaceuticals ranks #828 out of 1005 companies for OCF Yield %. This places Amylyx Pharmaceuticals in the lower half of its industry. The industry median OCF Yield % is 3.61. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Yield % for a Drug Manufacturers company?
The median OCF Yield % among Drug Manufacturers companies is 3.61, based on 1,005 companies in the industry. Companies in the top quartile (top 25%) have a OCF Yield % significantly above this median, while those in the bottom quartile fall well below. However, OCF Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Yield % mean?
A high OCF Yield % can signal that a stock is expensive relative to its fundamentals. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Amylyx Pharmaceuticals and its competitors. For the Drug Manufacturers industry, the median OCF Yield % is 3.61 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Amylyx Pharmaceuticals's current OCF Yield % is -6.09. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Amylyx Pharmaceuticals stock overvalued right now?
Amylyx Pharmaceuticals (AMLX) has a current OCF Yield % of -6.09. The current OCF Yield % is -6.09. Amylyx Pharmaceuticals' overall GF Score™ is 33/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Yield % calculated?
OCF Yield % is calculated from a company's financial statements. For Amylyx Pharmaceuticals (AMLX), the current OCF Yield % is -6.09 as of Jun. 26, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Amylyx Pharmaceuticals Business Description

Address 55 Cambridge Parkway, Suite 6W, Cambridge, MA, USA, 02142
Amylyx Pharmaceuticals Inc is a clinical-stage pharmaceutical company focused on developing novel therapies for communities with high unmet medical needs. The company has preclinical and clinical development programs in endocrine conditions and neurodegenerative diseases. Its pipeline includes investigational therapies matched with diseases based on mechanistic rationale, clinical outcomes, biomarkers, and preclinical data. The company is currently developing avexitide for Post-Bariatric Hypoglycemia, AMX0035 for Wolfram Syndrome, AMX0114 for Amyotrophic Lateral Sclerosis, and AMX0318 for Post-Bariatric Hypoglycemia and other rare diseases.
33GF Score

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