AMLX (Amylyx Pharmaceuticals) Altman Z2-Score: 7.81 (As of Jun. 26, 2026) — 81% Above Median


AMLX Amylyx Pharmaceuticals Inc AMLX
33 GF Score
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What is Amylyx Pharmaceuticals Altman Z2-Score?

Amylyx Pharmaceuticals AMLX -0.89% 33 Altman Z2-Score is 7.81 as of Jun. 26, 2026, which is 81% above its 10-year median of 4.31. GuruFocus rates AMLX with a GF Score™ of 33/100. The stock has 3 warning signs investors should review. Among 997 Drug Manufacturers companies, Amylyx Pharmaceuticals ranks better than 78.13% on this metric.

Altman Z2-Score, also known as Z"-Score, is used to predict the likelihood that a non-manufacturing company (excluding property/financial company) will face bankruptcy within a two-year period.

Good Sign:

Amylyx Pharmaceuticals has a Altman Z2-Score of 7.81, indicating it is in Safe Zones. This implies the Altman Z2-Score is strong.

The zones of discrimination were as such:

When Altman Z2-Score <= 1.1, it is in Distress Zones.
When Altman Z2-Score >= 2.6, it is in Safe Zones.
When Altman Z2-Score is between 1.1 and 2.6, it is in Grey Zones.

The historical rank and industry rank for Amylyx Pharmaceuticals's Altman Z2-Score or its related term are showing as below:

AMLX' s Altman Z2-Score Range Over the Past 10 Years
Min: -9.25   Med: 4.31   Max: 12.5
Current: 7.81

During the past 7 years, Amylyx Pharmaceuticals's highest Altman Z2-Score was 12.50. The lowest was -9.25. And the median was 4.31.


Amylyx Pharmaceuticals  (NAS:AMLX) Altman Z2-Score Explanation

The original Z-Score model was based on publicly traded manufacturing companies while the Z2-Score, also known as Z"-score can be used for any type of company excluding property/financial companies. Both Z-Score and Z2-Score describes the financial health of a company, and its likelihood of financial distress.

X1: The Working Capital/Total Assets (WC/TA) ratio is a measure of the net liquid assets of the firm relative to the total capitalization. Working capital is defined as the difference between current assets and current liabilities. Ordinarily, a firm experiencing consistent operating losses will have shrinking current assets in relation to total assets. Altman found this one proved to be the most valuable liquidity ratio comparing with the current ratio and the quick ratio. This is however the least significant of the five factors.

X2: Retained Earnings/Total Assets: the RE/TA ratio measures the leverage of a firm. Retained earnings is the account which reports the total amount of reinvested earnings and/or losses of a firm over its entire life. Those firms with high RE, relative to TA, have financed their assets through retention of profits and have not utilized as much debt.

X3, Earnings Before Interest and Taxes/Total Assets (EBIT/TA): This ratio is a measure of the true productivity of the firm's assets, independent of any tax or leverage factors. Since a firm's ultimate existence is based on the earning power of its assets, this ratio appears to be particularly appropriate for studies dealing with corporate failure. This ratio continually outperforms other profitability measures, including cash flow.

X4_2, Net Worth (Total Stockholders Equity - Preferred Stock)/Total Liabilities (NW/TL): it compares a company’s stock net worth with its total liabilities and can be used to assess the extent of its reliance on debt.

Read more about Altman Z2-Score, the original research on Z-Score and the additional research on Z2-Score.


Be Aware

Altman Z2-Score does not apply to financial companies.


Amylyx Pharmaceuticals Altman Z2-Score Related Terms


Amylyx Pharmaceuticals Altman Z2-Score Historical Data

* Premium members only.

The historical data trend for Amylyx Pharmaceuticals's Altman Z2-Score can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Amylyx Pharmaceuticals Altman Z2-Score Chart

Amylyx Pharmaceuticals Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Altman Z2-Score
Get a 7-Day Free Trial -5.59 6.31 9.05 -9.25 7.35

Amylyx Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Altman Z2-Score Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.25 -5.79 8.03 7.35 7.81

AMLX vs PRGO, ANIP, HROW: Altman Z2-Score Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Amylyx Pharmaceuticals's Altman Z2-Score, along with its competitors' market caps and Altman Z2-Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Amylyx Pharmaceuticals Altman Z2-Score vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Amylyx Pharmaceuticals's Altman Z2-Score distribution charts can be found below:

* The bar in red indicates where Amylyx Pharmaceuticals's Altman Z2-Score falls into.


AMLX
33GF Score
Amylyx Pharmaceuticals Inc AMLX
Altman Z2-Score is just one metric. See GF Score™, valuation, warning signs, and more.
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Amylyx Pharmaceuticals Altman Z2-Score Calculation

Altman Z-Score model is an accurate forecaster of failure up to two years prior to distress. It can be considered the assessment of the distress of industrial corporations.

Z2-Score, also known as Z"-Score is the Z-Score for non-manufacturing companies excluding property/financial companies.

Amylyx Pharmaceuticals's Altman Z2-Score for today is calculated with this formula:

Z=6.56*X1+3.26*X2+6.72*X3+1.05*X4_2
=6.56*0.9164+3.26*-2.6999+6.72*-0.5111+1.05*13.3627
=7.81

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency. GuruFocus does not calculate Altman Z2-Score when X4_2 value is 0.

Trailing Twelve Months (TTM) ended in Mar. 2026:
Total Assets was $293.60 Mil.
Total Current Assets was $285.02 Mil.
Total Current Liabilities was $15.97 Mil.
Retained Earnings was $-792.71 Mil.
Pre-Tax Income was -41.284 + -32.953 + -34.386 + -41.443 = $-150.07 Mil.
Interest Expense was 0 + 0 + 0 + 0 = $0.00 Mil.
Total Liabilities was $20.44 Mil.

* Note that for stock reported semi-annually or annually, GuruFocus uses latest annual data as the TTM data.

X1=Working Capital/Total Assets
=(Total Current Assets - Total Current Liabilities)/Total Assets
=(285.024 - 15.966)/293.603
=0.9164

X2=Retained Earnings/Total Assets
=-792.711/293.603
=-2.6999

X3=Earnings Before Interest and Taxes/Total Assets
=(Pre-Tax Income - Interest Expense)/Total Assets
=(-150.066 - 0)/293.603
=-0.5111

X4_2=Net Worth/Total Liabilities
=(Total Stockholders Equity - Preferred Stock)/Total Liabilities
=(273.161 - 0)/20.442
=13.3627

The zones of discrimination were as such:

Distress Zones - 1.1 < Grey Zones < 2.6 - Safe Zones

Amylyx Pharmaceuticals has a Altman Z2-Score of 7.81 indicating it is in Safe Zones.

Frequently Asked Questions Learn more about Altman Z2-Score →
What does a Altman Z2-Score of 7.81 mean?
Amylyx Pharmaceuticals (AMLX) has a Altman Z2-Score of 7.81 as of Jun. 26, 2026. Z2-Score is the Z-Score for non-manufacturing companies excluding property/financial companies, which measures a company's bankruptcy risk. View historical data on Amylyx Pharmaceuticals and its competitors. This is 81% above median its historical median of 4.31. According to the industry distribution chart, Amylyx Pharmaceuticals ranks #218 out of 997 companies in the Drug Manufacturers industry, placing it in the top 21.9%.
Is Amylyx Pharmaceuticals' Altman Z2-Score too high?
Amylyx Pharmaceuticals' current Altman Z2-Score of 7.81 is 81% above median its 10-year median of 4.31. The Drug Manufacturers industry median Altman Z2-Score is 3.87. Amylyx Pharmaceuticals' value of 7.81 is 101.8% above this industry median. Based on the distribution chart, Amylyx Pharmaceuticals ranks #218 out of 997 companies in the Drug Manufacturers industry, which is in the top quartile — a strong position relative to peers. Overall, Amylyx Pharmaceuticals has a GF Score™ of 33/100, reflecting its overall financial health beyond just this single metric.
How does Amylyx Pharmaceuticals' Altman Z2-Score compare to PRGO and ANIP?
According to the Drug Manufacturers industry distribution chart, Amylyx Pharmaceuticals ranks #218 out of 997 companies for Altman Z2-Score. This places Amylyx Pharmaceuticals in the top 22% of its industry — outperforming the majority of peers. The industry median Altman Z2-Score is 3.87. Amylyx Pharmaceuticals' value of 7.81 is 101.8% above this benchmark. While the company's 10-year median is 4.31 vs. the industry median of 3.87, Amylyx Pharmaceuticals has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Altman Z2-Score for a Drug Manufacturers company?
The median Altman Z2-Score among Drug Manufacturers companies is 3.87, based on 997 companies in the industry. Companies in the top quartile (top 25%) have a Altman Z2-Score significantly above this median, while those in the bottom quartile fall well below. However, Altman Z2-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Amylyx Pharmaceuticals's current Altman Z2-Score of 7.81 is 101.8% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Altman Z2-Score mean?
A high Altman Z2-Score can signal that a stock is expensive relative to its fundamentals. Z2-Score is the Z-Score for non-manufacturing companies excluding property/financial companies, which measures a company's bankruptcy risk. View historical data on Amylyx Pharmaceuticals and its competitors. For the Drug Manufacturers industry, the median Altman Z2-Score is 3.87 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Amylyx Pharmaceuticals's current Altman Z2-Score is 7.81, which is 81% above median its own 10-year median of 4.31. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Amylyx Pharmaceuticals stock overvalued right now?
Amylyx Pharmaceuticals (AMLX) has a current Altman Z2-Score of 7.81. The current Altman Z2-Score is 7.81, which is 81% above median its 10-year median of 4.31 and 101.8% above the Drug Manufacturers industry median of 3.87. Amylyx Pharmaceuticals' overall GF Score™ is 33/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Altman Z2-Score calculated?
Altman Z2-Score is calculated from a company's financial statements. For Amylyx Pharmaceuticals (AMLX), the current Altman Z2-Score is 7.81 as of Jun. 26, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Amylyx Pharmaceuticals Business Description

Address 55 Cambridge Parkway, Suite 6W, Cambridge, MA, USA, 02142
Amylyx Pharmaceuticals Inc is a clinical-stage pharmaceutical company focused on developing novel therapies for communities with high unmet medical needs. The company has preclinical and clinical development programs in endocrine conditions and neurodegenerative diseases. Its pipeline includes investigational therapies matched with diseases based on mechanistic rationale, clinical outcomes, biomarkers, and preclinical data. The company is currently developing avexitide for Post-Bariatric Hypoglycemia, AMX0035 for Wolfram Syndrome, AMX0114 for Amyotrophic Lateral Sclerosis, and AMX0318 for Post-Bariatric Hypoglycemia and other rare diseases.
33GF Score

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