ALEC (Alector) EBITDA Margin %: -2,183.08% (As of Mar. 2026)


ALEC Alector Inc ALEC
29 GF Score
Price $1.80
GF Value $0.73
Valuation Significantly Overvalued
! 7 Warning Signs
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What is Alector EBITDA Margin %?

Alector ALEC -1.65% 29 EBITDA Margin % is -2,183.08% as of Mar. 2026. GuruFocus rates ALEC with a GF Score™ of 29/100 and a GF Value™ of $0.73 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 945 Biotechnology companies, Alector ranks worse than 75.56% on this metric.

EBITDA Margin % is calculated as EBITDA divided by its Revenue. Alector's EBITDA for the three months ended in Mar. 2026 was $-22.84 Mil. Alector's Revenue for the three months ended in Mar. 2026 was $1.05 Mil. Therefore, Alector's EBITDA margin for the quarter that ended in Mar. 2026 was -2,183.08%.


Alector  (NAS:ALEC) EBITDA Margin % Explanation

EBITDA Margin % is the ratio of EBITDA divided by net sales or Revenue. It is an performance metric measuring company's operating profitability. EBITDA Margin takes depreciation and amortization, interest expense and tax into account, which makes it easy to compare the relative profitability of companies of different sizes in the same industry.


Alector EBITDA Margin % Related Terms


Alector EBITDA Margin % Historical Data

* Premium members only.

The historical data trend for Alector's EBITDA Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Alector EBITDA Margin % Chart

Alector Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EBITDA Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -14.03 -96.82 -147.22 -135.40 -695.40

Alector Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EBITDA Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1,166.22 -392.63 -1,082.09 -598.16 -2,183.08

ALEC vs SLGL, LENZ, CNXU: EBITDA Margin % Comparison

For the Biotechnology subindustry, Alector's EBITDA Margin %, along with its competitors' market caps and EBITDA Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Alector EBITDA Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Alector's EBITDA Margin % distribution charts can be found below:

* The bar in red indicates where Alector's EBITDA Margin % falls into.


ALEC
29GF Score
Alector Inc ALEC
EBITDA Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Alector EBITDA Margin % Calculation

EBITDA margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent.

Alector's EBITDA Margin % for the fiscal year that ended in Dec. 2025 is calculated as

EBITDA Margin %=EBITDA (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-146.346/21.045
=-695.40 %

Alector's EBITDA Margin % for the quarter that ended in Mar. 2026 is calculated as

EBITDA Margin %=EBITDA (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-22.835/1.046
=-2,183.08 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EBITDA Margin % →
What does a EBITDA Margin % of -2,183.08% mean?
Alector (ALEC) has a EBITDA Margin % of -2,183.08% as of Mar. 2026. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Alector and its competitors. According to the industry distribution chart, Alector ranks #714 out of 945 companies in the Biotechnology industry, placing it in the top 75.6%.
Is Alector's EBITDA Margin % too high?
Alector's current EBITDA Margin % is -2,183.08%. Based on the distribution chart, Alector ranks #714 out of 945 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Alector has a GF Score™ of 29/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Alector's EBITDA Margin % compare to SLGL and LENZ?
According to the Biotechnology industry distribution chart, Alector ranks #714 out of 945 companies for EBITDA Margin %. This places Alector in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBITDA Margin % for a Biotechnology company?
A good EBITDA Margin % depends on the Biotechnology industry context. However, EBITDA Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBITDA Margin % mean?
A high EBITDA Margin % can signal that a stock is expensive relative to its fundamentals. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Alector and its competitors. Alector's current EBITDA Margin % is -2,183.08%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Alector stock overvalued right now?
Based on GuruFocus' analysis, Alector (ALEC) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.73, compared to a current price of $1.80 — trading 146.6% above its estimated fair value. The current EBITDA Margin % is -2,183.08%. Alector's overall GF Score™ is 29/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBITDA Margin % calculated?
EBITDA Margin % is calculated from a company's financial statements. For Alector (ALEC), the current EBITDA Margin % is -2,183.08% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Alector (ALEC) Overvalued in 2026?

Based on GuruFocus' analysis, Alector stock appears to be overvalued. The current stock price of $1.80 is trading 146.6% above its estimated GF Value™ of $0.73. GuruFocus considers Alector to be Significantly Overvalued.

Key valuation signals for ALEC:

  • EBITDA Margin %: -2,183.08%
  • GF Value™: $0.73 vs. price of $1.80 (146.6% above fair value)
  • GF Score™: 29/100 with 7 warning signs

No single metric tells the full story. See the ALEC stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Alector Business Description

Address 131 Oyster Point Boulevard, Suite 600, South San Francisco, CA, USA, 94080
Alector Inc is a clinical-stage biotechnology company focused on developing therapies for neurodegenerative diseases. The company advances a pipeline of product candidates including Nivisnebart (AL101/GSK4527226) for Alzheimer's disease, AL137 for Alzheimer's disease, AL050 for Parkinson's disease and Lewy body dementia, and AL064, an siRNA program targeting tau for Alzheimer's disease and other tauopathies, supported by its proprietary Alector Brain Carrier (ABC) platform designed to improve delivery of therapeutics across the blood-brain barrier.
29GF Score

Get the complete analysis for ALEC

EBITDA Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.80
Price
$0.73
GF Value