ALEC (Alector) Pretax Margin %: -2,192.16% (As of Mar. 2026)


ALEC Alector Inc ALEC
30 GF Score
Price $1.98
GF Value $0.73
Valuation Significantly Overvalued
! 7 Warning Signs
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What is Alector Pretax Margin %?

Alector ALEC +9.72% 30 Pretax Margin % is -2,192.16% as of Mar. 2026. GuruFocus rates ALEC with a GF Score™ of 30/100 and a GF Value™ of $0.73 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 947 Biotechnology companies, Alector ranks worse than 74.13% on this metric.

Pre-Tax margin is calculated as Pre-Tax Income divided by its Revenue. Alector's Pre-Tax Income for the three months ended in Mar. 2026 was $-22.93 Mil. Alector's Revenue for the three months ended in Mar. 2026 was $1.05 Mil. Therefore, Alector's pretax margin for the quarter that ended in Mar. 2026 was -2,192.16%.

The historical rank and industry rank for Alector's Pretax Margin % or its related term are showing as below:

ALEC' s Pretax Margin % Range Over the Past 10 Years
Min: -3632.21   Med: -342.72   Max: -17.54
Current: -679.92


ALEC's Pretax Margin % is ranked worse than
74.13% of 947 companies
in the Biotechnology industry
Industry Median: -90.63 vs ALEC: -679.92

Alector  (NAS:ALEC) Pretax Margin % Explanation

The pretax margin, as know as pretax profit margin, is widely used to measure the operating efficiency of a company before deducting taxes.

The pretax margin is sometimes preferred over the net margin as tax expenditures can make profitability comparisons between companies misleading.

It is a useful tool to compare companies operating in the same sector and less effective when comparing companies from other sectors as each industry generally has different operating expenses and sales patterns.

The long term trend of the pretax margin is a good indicator of the competitiveness and health of the business.


Alector Pretax Margin % Related Terms


Alector Pretax Margin % Historical Data

* Premium members only.

The historical data trend for Alector's Pretax Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Alector Pretax Margin % Chart

Alector Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Pretax Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -17.54 -97.33 -128.97 -118.26 -678.36

Alector Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Pretax Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1,101.55 -387.66 -1,063.40 -594.82 -2,192.16

ALEC vs SLGL, LENZ, CNXU: Pretax Margin % Comparison

For the Biotechnology subindustry, Alector's Pretax Margin %, along with its competitors' market caps and Pretax Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Alector Pretax Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Alector's Pretax Margin % distribution charts can be found below:

* The bar in red indicates where Alector's Pretax Margin % falls into.


ALEC
30GF Score
Alector Inc ALEC
Pretax Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Alector Pretax Margin % Calculation

Pretax margin - also known as pretax profit margin is the ratio of Pretax Income divided by net sales or Revenue, usually presented in percent.

Alector's Pretax Margin for the fiscal year that ended in Dec. 2025 is calculated as

Pretax Margin=Pre-Tax Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-142.761/21.045
=-678.36 %

Alector's Pretax Margin for the quarter that ended in Mar. 2026 is calculated as

Pretax Margin=Pre-Tax Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-22.93/1.046
=-2,192.16 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Pretax Margin % →
What does a Pretax Margin % of -2,192.16% mean?
Alector (ALEC) has a Pretax Margin % of -2,192.16% as of Mar. 2026. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Alector and its competitors. According to the industry distribution chart, Alector ranks #702 out of 947 companies in the Biotechnology industry, placing it in the top 74.1%.
Is Alector's Pretax Margin % too high?
Alector's current Pretax Margin % is -2,192.16%. Based on the distribution chart, Alector ranks #702 out of 947 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Alector has a GF Score™ of 30/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Alector's Pretax Margin % compare to SLGL and LENZ?
According to the Biotechnology industry distribution chart, Alector ranks #702 out of 947 companies for Pretax Margin %. This places Alector in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Pretax Margin % for a Biotechnology company?
A good Pretax Margin % depends on the Biotechnology industry context. However, Pretax Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Pretax Margin % mean?
A high Pretax Margin % can signal that a stock is expensive relative to its fundamentals. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Alector and its competitors. Alector's current Pretax Margin % is -2,192.16%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Alector stock overvalued right now?
Based on GuruFocus' analysis, Alector (ALEC) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.73, compared to a current price of $1.98 — trading 170.5% above its estimated fair value. The current Pretax Margin % is -2,192.16%. Alector's overall GF Score™ is 30/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Pretax Margin % calculated?
Pretax Margin % is calculated from a company's financial statements. For Alector (ALEC), the current Pretax Margin % is -2,192.16% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Alector (ALEC) Overvalued in 2026?

Based on GuruFocus' analysis, Alector stock appears to be overvalued. The current stock price of $1.98 is trading 170.5% above its estimated GF Value™ of $0.73. GuruFocus considers Alector to be Significantly Overvalued.

Key valuation signals for ALEC:

  • Pretax Margin %: -2,192.16%
  • GF Value™: $0.73 vs. price of $1.98 (170.5% above fair value)
  • GF Score™: 30/100 with 7 warning signs

No single metric tells the full story. See the ALEC stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Alector Business Description

Address 131 Oyster Point Boulevard, Suite 600, South San Francisco, CA, USA, 94080
Alector Inc is a clinical-stage biotechnology company focused on developing therapies for neurodegenerative diseases. The company advances a pipeline of product candidates including Nivisnebart (AL101/GSK4527226) for Alzheimer's disease, AL137 for Alzheimer's disease, AL050 for Parkinson's disease and Lewy body dementia, and AL064, an siRNA program targeting tau for Alzheimer's disease and other tauopathies, supported by its proprietary Alector Brain Carrier (ABC) platform designed to improve delivery of therapeutics across the blood-brain barrier.
30GF Score

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Pretax Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.98
Price
$0.73
GF Value