Syndax Pharmaceuticals (FRA:1T3) EBITDA Margin %: -47.52% (As of Mar. 2026)


FRA:1T3 Syndax Pharmaceuticals Inc FRA:1T3
25 GF Score
Price €17.43
! 7 Warning Signs
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What is Syndax Pharmaceuticals EBITDA Margin %?

Syndax Pharmaceuticals FRA:1T3 -0.94% 25 EBITDA Margin % is -47.52% as of Mar. 2026. GuruFocus rates FRA:1T3 with a GF Score™ of 25/100. The stock has 7 warning signs investors should review. Among 944 Biotechnology companies, Syndax Pharmaceuticals ranks worse than 53.18% on this metric.

EBITDA Margin % is calculated as EBITDA divided by its Revenue. Syndax Pharmaceuticals's EBITDA for the three months ended in Mar. 2026 was €-26.7 Mil. Syndax Pharmaceuticals's Revenue for the three months ended in Mar. 2026 was €56.1 Mil. Therefore, Syndax Pharmaceuticals's EBITDA margin for the quarter that ended in Mar. 2026 was -47.52%.


Syndax Pharmaceuticals  (FRA:1T3) EBITDA Margin % Explanation

EBITDA Margin % is the ratio of EBITDA divided by net sales or Revenue. It is an performance metric measuring company's operating profitability. EBITDA Margin takes depreciation and amortization, interest expense and tax into account, which makes it easy to compare the relative profitability of companies of different sizes in the same industry.


Syndax Pharmaceuticals EBITDA Margin % Related Terms


Syndax Pharmaceuticals EBITDA Margin % Historical Data

* Premium members only.

The historical data trend for Syndax Pharmaceuticals's EBITDA Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Syndax Pharmaceuticals EBITDA Margin % Chart

Syndax Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EBITDA Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 19.23 0.00 0.00 -1,325.28 -146.00

Syndax Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EBITDA Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -383.17 -168.57 -114.30 -85.00 -47.52

FRA:1T3 vs CAPR, SLS, AGIO: EBITDA Margin % Comparison

For the Biotechnology subindustry, Syndax Pharmaceuticals's EBITDA Margin %, along with its competitors' market caps and EBITDA Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Syndax Pharmaceuticals EBITDA Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Syndax Pharmaceuticals's EBITDA Margin % distribution charts can be found below:

* The bar in red indicates where Syndax Pharmaceuticals's EBITDA Margin % falls into.


FRA:1T3
25GF Score
Syndax Pharmaceuticals Inc FRA:1T3
EBITDA Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Syndax Pharmaceuticals EBITDA Margin % Calculation

EBITDA margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent.

Syndax Pharmaceuticals's EBITDA Margin % for the fiscal year that ended in Dec. 2025 is calculated as

EBITDA Margin %=EBITDA (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-214.893/147.189
=-146.00 %

Syndax Pharmaceuticals's EBITDA Margin % for the quarter that ended in Mar. 2026 is calculated as

EBITDA Margin %=EBITDA (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-26.662/56.107
=-47.52 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EBITDA Margin % →
What does a EBITDA Margin % of -47.52% mean?
Syndax Pharmaceuticals (FRA:1T3) has a EBITDA Margin % of -47.52% as of Mar. 2026. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Syndax Pharmaceuticals and its competitors. According to the industry distribution chart, Syndax Pharmaceuticals ranks #502 out of 944 companies in the Biotechnology industry, placing it in the top 53.2%.
Is Syndax Pharmaceuticals' EBITDA Margin % too high?
Syndax Pharmaceuticals' current EBITDA Margin % is -47.52%. Based on the distribution chart, Syndax Pharmaceuticals ranks #502 out of 944 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Syndax Pharmaceuticals has a GF Score™ of 25/100, reflecting its overall financial health beyond just this single metric.
How does Syndax Pharmaceuticals' EBITDA Margin % compare to CAPR and SLS?
According to the Biotechnology industry distribution chart, Syndax Pharmaceuticals ranks #502 out of 944 companies for EBITDA Margin %. This places Syndax Pharmaceuticals in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBITDA Margin % for a Biotechnology company?
A good EBITDA Margin % depends on the Biotechnology industry context. However, EBITDA Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBITDA Margin % mean?
A high EBITDA Margin % can signal that a stock is expensive relative to its fundamentals. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Syndax Pharmaceuticals and its competitors. Syndax Pharmaceuticals's current EBITDA Margin % is -47.52%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Syndax Pharmaceuticals stock overvalued right now?
Syndax Pharmaceuticals (FRA:1T3) has a current EBITDA Margin % of -47.52%. The current EBITDA Margin % is -47.52%. Syndax Pharmaceuticals' overall GF Score™ is 25/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBITDA Margin % calculated?
EBITDA Margin % is calculated from a company's financial statements. For Syndax Pharmaceuticals (FRA:1T3), the current EBITDA Margin % is -47.52% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Syndax Pharmaceuticals Business Description

Other Exchanges SNDX:USA1T3:Germany
Address 730 Third Avenue, 9th Floor, New York, NY, USA, 10017
Syndax Pharmaceuticals Inc is a clinical-stage biopharmaceutical company focused on developing a pipeline of combination therapies in multiple cancer indications. Its product candidates include revumenib and axatilimab. It is developing revumenib, a selective menin-MLL inhibitor for KMT2A-rearranged (MLL-r) and NPM1-mutant acute leukemias, including ALL and AML. It is also developing axatilimab, a CSF-1R-blocking antibody for cGVHD and idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells. The business activity of the group is functioned through the region of the United States.
25GF Score

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EBITDA Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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