Syndax Pharmaceuticals (FRA:1T3) ROA %: -34.29% (As of Mar. 2026)


FRA:1T3 Syndax Pharmaceuticals Inc FRA:1T3
25 GF Score
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What is Syndax Pharmaceuticals ROA %?

Syndax Pharmaceuticals FRA:1T3 -0.94% 25 ROA % is -34.29% as of Mar. 2026. GuruFocus rates FRA:1T3 with a GF Score™ of 25/100. The stock has 7 warning signs investors should review. Among 1,419 Biotechnology companies, Syndax Pharmaceuticals ranks worse than 58.56% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Syndax Pharmaceuticals's annualized Net Income for the quarter that ended in Mar. 2026 was €-147.6 Mil. Syndax Pharmaceuticals's average Total Assets over the quarter that ended in Mar. 2026 was €430.6 Mil. Therefore, Syndax Pharmaceuticals's annualized ROA % for the quarter that ended in Mar. 2026 was -34.29%.

The historical rank and industry rank for Syndax Pharmaceuticals's ROA % or its related term are showing as below:

FRA:1T3' s ROA % Range Over the Past 10 Years
Min: -76.02   Med: -45.11   Max: 6.64
Current: -43.58

During the past 13 years, Syndax Pharmaceuticals's highest ROA % was 6.64%. The lowest was -76.02%. And the median was -45.11%.

FRA:1T3's ROA % is ranked worse than
58.56% of 1419 companies
in the Biotechnology industry
Industry Median: -32.84 vs FRA:1T3: -43.58

Syndax Pharmaceuticals  (FRA:1T3) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Mar. 2026 )
=Net Income/Total Assets
=-147.648/430.6135
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-147.648 / 224.428)*(224.428 / 430.6135)
=Net Margin %*Asset Turnover
=-65.79 %*0.5212
=-34.29 %

Note: The Net Income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Syndax Pharmaceuticals ROA % Related Terms


Syndax Pharmaceuticals ROA % Historical Data

* Premium members only.

The historical data trend for Syndax Pharmaceuticals's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Syndax Pharmaceuticals ROA % Chart

Syndax Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 6.84 -32.51 -37.23 -48.54 -42.59

Syndax Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -48.87 -44.91 -41.93 -50.37 -34.29

FRA:1T3 vs IOVA, GLUE, TYRA: ROA % Comparison

For the Biotechnology subindustry, Syndax Pharmaceuticals's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Syndax Pharmaceuticals ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Syndax Pharmaceuticals's ROA % distribution charts can be found below:

* The bar in red indicates where Syndax Pharmaceuticals's ROA % falls into.


FRA:1T3
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Syndax Pharmaceuticals Inc FRA:1T3
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Syndax Pharmaceuticals ROA % Calculation

Syndax Pharmaceuticals's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=-243.75/( (692.199+452.369)/ 2 )
=-243.75/572.284
=-42.59 %

Syndax Pharmaceuticals's annualized ROA % for the quarter that ended in Mar. 2026 is calculated as:

ROA %=Net Income (Q: Mar. 2026 )/( (Total Assets (Q: Dec. 2025 )+Total Assets (Q: Mar. 2026 ))/ count )
=-147.648/( (452.369+408.858)/ 2 )
=-147.648/430.6135
=-34.29 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Mar. 2026) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -34.29% mean?
Syndax Pharmaceuticals (FRA:1T3) has a ROA % of -34.29% as of Mar. 2026. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Syndax Pharmaceuticals and its competitors. According to the industry distribution chart, Syndax Pharmaceuticals ranks #831 out of 1419 companies in the Biotechnology industry, placing it in the top 58.6%.
Is Syndax Pharmaceuticals' ROA % too high?
Syndax Pharmaceuticals' current ROA % is -34.29%. Based on the distribution chart, Syndax Pharmaceuticals ranks #831 out of 1419 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Syndax Pharmaceuticals has a GF Score™ of 25/100, reflecting its overall financial health beyond just this single metric.
How does Syndax Pharmaceuticals' ROA % compare to IOVA and GLUE?
According to the Biotechnology industry distribution chart, Syndax Pharmaceuticals ranks #831 out of 1419 companies for ROA %. This places Syndax Pharmaceuticals in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Syndax Pharmaceuticals and its competitors. Syndax Pharmaceuticals's current ROA % is -34.29%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Syndax Pharmaceuticals stock overvalued right now?
Syndax Pharmaceuticals (FRA:1T3) has a current ROA % of -34.29%. The current ROA % is -34.29%. Syndax Pharmaceuticals' overall GF Score™ is 25/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Syndax Pharmaceuticals (FRA:1T3), the current ROA % is -34.29% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Syndax Pharmaceuticals Business Description

Other Exchanges SNDX:USA1T3:Germany
Address 730 Third Avenue, 9th Floor, New York, NY, USA, 10017
Syndax Pharmaceuticals Inc is a clinical-stage biopharmaceutical company focused on developing a pipeline of combination therapies in multiple cancer indications. Its product candidates include revumenib and axatilimab. It is developing revumenib, a selective menin-MLL inhibitor for KMT2A-rearranged (MLL-r) and NPM1-mutant acute leukemias, including ALL and AML. It is also developing axatilimab, a CSF-1R-blocking antibody for cGVHD and idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells. The business activity of the group is functioned through the region of the United States.
25GF Score

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