Syndax Pharmaceuticals (FRA:1T3) Cyclically Adjusted Book per Share: €4.07 (As of Mar. 2026)


FRA:1T3 Syndax Pharmaceuticals Inc FRA:1T3
25 GF Score
Price €21.28
! 9 Warning Signs
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What is Syndax Pharmaceuticals Cyclically Adjusted Book per Share?

Syndax Pharmaceuticals FRA:1T3 -0.61% 25 Cyclically Adjusted Book per Share is €4.07 as of Mar. 2026. GuruFocus rates FRA:1T3 with a GF Score™ of 25/100. The stock has 9 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

Syndax Pharmaceuticals's adjusted book value per share for the three months ended in Mar. 2026 was €0.407. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is €4.07 for the trailing ten years ended in Mar. 2026.

During the past 12 months, Syndax Pharmaceuticals's average Cyclically Adjusted Book Growth Rate was 24.00% per year. During the past 3 years, the average Cyclically Adjusted Book Growth Rate was 56.70% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

During the past 13 years, the highest 3-Year average Cyclically Adjusted Book Growth Rate of Syndax Pharmaceuticals was 56.70% per year. The lowest was 56.70% per year. And the median was 56.70% per year.

As of today (2026-07-11), Syndax Pharmaceuticals's current stock price is €21.28. Syndax Pharmaceuticals's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was €4.07. Syndax Pharmaceuticals's Cyclically Adjusted PB Ratio of today is 5.23.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Syndax Pharmaceuticals was 30.59. The lowest was 2.31. And the median was 6.68.


Syndax Pharmaceuticals  (FRA:1T3) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Syndax Pharmaceuticals's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=21.28/4.07
=5.23

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Syndax Pharmaceuticals was 30.59. The lowest was 2.31. And the median was 6.68.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


Syndax Pharmaceuticals Cyclically Adjusted Book per Share Related Terms


Syndax Pharmaceuticals Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for Syndax Pharmaceuticals's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Syndax Pharmaceuticals Cyclically Adjusted Book per Share Chart

Syndax Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 1.15 1.88 3.50 2.93

Syndax Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 3.76 3.14 3.72 2.93 4.07

FRA:1T3 vs IOVA, GLUE, TYRA: Cyclically Adjusted Book per Share Comparison

For the Biotechnology subindustry, Syndax Pharmaceuticals's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Syndax Pharmaceuticals Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Syndax Pharmaceuticals's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Syndax Pharmaceuticals's Cyclically Adjusted PB Ratio falls into.


FRA:1T3
25GF Score
Syndax Pharmaceuticals Inc FRA:1T3
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
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Syndax Pharmaceuticals Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Syndax Pharmaceuticals's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book= Book Value per Share /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.407/330.2130*330.2130
=0.407

Current CPI (Mar. 2026) = 330.2130.

Syndax Pharmaceuticals Quarterly Data

Book Value per Share CPI Adj_Book
201606 5.321 241.018 7.290
201609 4.599 241.428 6.290
201612 4.379 241.432 5.989
201703 3.721 243.801 5.040
201706 4.379 244.955 5.903
201709 3.637 246.819 4.866
201712 3.614 246.524 4.841
201803 2.855 249.554 3.778
201806 2.652 251.989 3.475
201809 2.290 252.439 2.996
201812 1.877 251.233 2.467
201903 2.241 254.202 2.911
201906 1.804 256.143 2.326
201909 1.474 256.759 1.896
201912 1.048 256.974 1.347
202003 1.601 258.115 2.048
202006 3.404 257.797 4.360
202009 2.885 260.280 3.660
202012 4.329 260.474 5.488
202103 3.973 264.877 4.953
202106 3.663 271.696 4.452
202109 3.463 274.310 4.169
202112 6.573 278.802 7.785
202203 6.180 287.504 7.098
202206 6.071 296.311 6.766
202209 5.680 296.808 6.319
202212 6.479 296.797 7.208
202303 5.939 301.836 6.497
202306 5.318 305.109 5.756
202309 4.833 307.789 5.185
202312 5.991 306.746 6.449
202403 5.325 312.332 5.630
202406 4.745 314.175 4.987
202409 3.871 315.301 4.054
202412 3.211 315.605 3.360
202503 2.312 319.799 2.387
202506 1.586 322.561 1.624
202509 1.132 324.800 1.151
202512 0.631 324.054 0.643
202603 0.407 330.213 0.407

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of €4.07 mean?
Syndax Pharmaceuticals (FRA:1T3) has a Cyclically Adjusted Book per Share of €4.07 as of Mar. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Syndax Pharmaceuticals and its competitors.
Is Syndax Pharmaceuticals' Cyclically Adjusted Book per Share too high?
Syndax Pharmaceuticals' current Cyclically Adjusted Book per Share is €4.07. Overall, Syndax Pharmaceuticals has a GF Score™ of 25/100, reflecting its overall financial health beyond just this single metric.
How does Syndax Pharmaceuticals' Cyclically Adjusted Book per Share compare to IOVA and GLUE?
Syndax Pharmaceuticals' Cyclically Adjusted Book per Share of €4.07 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Biotechnology company?
A good Cyclically Adjusted Book per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Syndax Pharmaceuticals and its competitors. Syndax Pharmaceuticals's current Cyclically Adjusted Book per Share is €4.07. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Syndax Pharmaceuticals stock overvalued right now?
Syndax Pharmaceuticals (FRA:1T3) has a current Cyclically Adjusted Book per Share of €4.07. The current Cyclically Adjusted Book per Share is €4.07. Syndax Pharmaceuticals' overall GF Score™ is 25/100 with 9 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For Syndax Pharmaceuticals (FRA:1T3), the current Cyclically Adjusted Book per Share is €4.07 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Syndax Pharmaceuticals Business Description

Other Exchanges SNDX:USA1T3:Germany
Address 730 Third Avenue, 9th Floor, New York, NY, USA, 10017
Syndax Pharmaceuticals Inc is a clinical-stage biopharmaceutical company focused on developing a pipeline of combination therapies in multiple cancer indications. Its product candidates include revumenib and axatilimab. It is developing revumenib, a selective menin-MLL inhibitor for KMT2A-rearranged (MLL-r) and NPM1-mutant acute leukemias, including ALL and AML. It is also developing axatilimab, a CSF-1R-blocking antibody for cGVHD and idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells. The business activity of the group is functioned through the region of the United States.
25GF Score

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Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€21.28
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