Syndax Pharmaceuticals (FRA:1T3) Pretax Margin %: -65.79% (As of Mar. 2026)


FRA:1T3 Syndax Pharmaceuticals Inc FRA:1T3
25 GF Score
Price €19.00
! 7 Warning Signs
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What is Syndax Pharmaceuticals Pretax Margin %?

Syndax Pharmaceuticals FRA:1T3 +4.37% 25 Pretax Margin % is -65.79% as of Mar. 2026. GuruFocus rates FRA:1T3 with a GF Score™ of 25/100. The stock has 7 warning signs investors should review. Among 941 Biotechnology companies, Syndax Pharmaceuticals ranks worse than 52.07% on this metric.

Pre-Tax margin is calculated as Pre-Tax Income divided by its Revenue. Syndax Pharmaceuticals's Pre-Tax Income for the three months ended in Mar. 2026 was €-36.9 Mil. Syndax Pharmaceuticals's Revenue for the three months ended in Mar. 2026 was €56.1 Mil. Therefore, Syndax Pharmaceuticals's pretax margin for the quarter that ended in Mar. 2026 was -65.79%.

The historical rank and industry rank for Syndax Pharmaceuticals's Pretax Margin % or its related term are showing as below:

FRA:1T3' s Pretax Margin % Range Over the Past 10 Years
Min: -4875.48   Med: -3264.8   Max: 17.84
Current: -111.88


FRA:1T3's Pretax Margin % is ranked worse than
52.07% of 941 companies
in the Biotechnology industry
Industry Median: -90.37 vs FRA:1T3: -111.88

Syndax Pharmaceuticals  (FRA:1T3) Pretax Margin % Explanation

The pretax margin, as know as pretax profit margin, is widely used to measure the operating efficiency of a company before deducting taxes.

The pretax margin is sometimes preferred over the net margin as tax expenditures can make profitability comparisons between companies misleading.

It is a useful tool to compare companies operating in the same sector and less effective when comparing companies from other sectors as each industry generally has different operating expenses and sales patterns.

The long term trend of the pretax margin is a good indicator of the competitiveness and health of the business.


Syndax Pharmaceuticals Pretax Margin % Related Terms


Syndax Pharmaceuticals Pretax Margin % Historical Data

* Premium members only.

The historical data trend for Syndax Pharmaceuticals's Pretax Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Syndax Pharmaceuticals Pretax Margin % Chart

Syndax Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Pretax Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 17.84 0.00 0.00 -1,346.13 -165.60

Syndax Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Pretax Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -423.34 -189.28 -132.36 -98.96 -65.79

FRA:1T3 vs IOVA, GLUE, TYRA: Pretax Margin % Comparison

For the Biotechnology subindustry, Syndax Pharmaceuticals's Pretax Margin %, along with its competitors' market caps and Pretax Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Syndax Pharmaceuticals Pretax Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Syndax Pharmaceuticals's Pretax Margin % distribution charts can be found below:

* The bar in red indicates where Syndax Pharmaceuticals's Pretax Margin % falls into.


FRA:1T3
25GF Score
Syndax Pharmaceuticals Inc FRA:1T3
Pretax Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Syndax Pharmaceuticals Pretax Margin % Calculation

Pretax margin - also known as pretax profit margin is the ratio of Pretax Income divided by net sales or Revenue, usually presented in percent.

Syndax Pharmaceuticals's Pretax Margin for the fiscal year that ended in Dec. 2025 is calculated as

Pretax Margin=Pre-Tax Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-243.75/147.189
=-165.60 %

Syndax Pharmaceuticals's Pretax Margin for the quarter that ended in Mar. 2026 is calculated as

Pretax Margin=Pre-Tax Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-36.912/56.107
=-65.79 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Pretax Margin % →
What does a Pretax Margin % of -65.79% mean?
Syndax Pharmaceuticals (FRA:1T3) has a Pretax Margin % of -65.79% as of Mar. 2026. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Syndax Pharmaceuticals and its competitors. According to the industry distribution chart, Syndax Pharmaceuticals ranks #490 out of 941 companies in the Biotechnology industry, placing it in the top 52.1%.
Is Syndax Pharmaceuticals' Pretax Margin % too high?
Syndax Pharmaceuticals' current Pretax Margin % is -65.79%. Based on the distribution chart, Syndax Pharmaceuticals ranks #490 out of 941 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Syndax Pharmaceuticals has a GF Score™ of 25/100, reflecting its overall financial health beyond just this single metric.
How does Syndax Pharmaceuticals' Pretax Margin % compare to IOVA and GLUE?
According to the Biotechnology industry distribution chart, Syndax Pharmaceuticals ranks #490 out of 941 companies for Pretax Margin %. This places Syndax Pharmaceuticals in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Pretax Margin % for a Biotechnology company?
A good Pretax Margin % depends on the Biotechnology industry context. However, Pretax Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Pretax Margin % mean?
A high Pretax Margin % can signal that a stock is expensive relative to its fundamentals. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Syndax Pharmaceuticals and its competitors. Syndax Pharmaceuticals's current Pretax Margin % is -65.79%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Syndax Pharmaceuticals stock overvalued right now?
Syndax Pharmaceuticals (FRA:1T3) has a current Pretax Margin % of -65.79%. The current Pretax Margin % is -65.79%. Syndax Pharmaceuticals' overall GF Score™ is 25/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Pretax Margin % calculated?
Pretax Margin % is calculated from a company's financial statements. For Syndax Pharmaceuticals (FRA:1T3), the current Pretax Margin % is -65.79% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Syndax Pharmaceuticals Business Description

Other Exchanges SNDX:USA1T3:Germany
Address 730 Third Avenue, 9th Floor, New York, NY, USA, 10017
Syndax Pharmaceuticals Inc is a clinical-stage biopharmaceutical company focused on developing a pipeline of combination therapies in multiple cancer indications. Its product candidates include revumenib and axatilimab. It is developing revumenib, a selective menin-MLL inhibitor for KMT2A-rearranged (MLL-r) and NPM1-mutant acute leukemias, including ALL and AML. It is also developing axatilimab, a CSF-1R-blocking antibody for cGVHD and idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells. The business activity of the group is functioned through the region of the United States.
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