4SC AG (FRA:VSC) EBITDA Margin %: 1.61% (As of Dec. 2025)

What is 4SC AG EBITDA Margin %?

4SC AG FRA:VSC EBITDA Margin % is 1.61% as of Dec. 2025. The stock has 7 warning signs investors should review.

EBITDA Margin % is calculated as EBITDA divided by its Revenue. 4SC AG's EBITDA for the six months ended in Dec. 2025 was €0.04 Mil. 4SC AG's Revenue for the six months ended in Dec. 2025 was €2.55 Mil. Therefore, 4SC AG's EBITDA margin for the quarter that ended in Dec. 2025 was 1.61%.

4SC AG (FRA:VSC) EBITDA Margin % Explanation

EBITDA Margin % is the ratio of EBITDA divided by net sales or Revenue. It is an performance metric measuring company's operating profitability. EBITDA Margin takes depreciation and amortization, interest expense and tax into account, which makes it easy to compare the relative profitability of companies of different sizes in the same industry.

4SC AG EBITDA Margin % Related Terms

4SC AG EBITDA Margin % Historical Data

* Premium members only.

The historical data trend for 4SC AG's EBITDA Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

4SC AG EBITDA Margin % Chart

4SC AG Annual Data

Trend

Dec16

Dec17

Dec18

Dec19

Dec20

Dec21

Dec22

Dec23

Dec24

Dec25

EBITDA Margin %

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-62.20

-2,888.30

-2,496.05

-2,234.23

-112.68

4SC AG Semi-Annual Data
	Jun16	Dec16	Jun17	Dec17	Jun18	Dec18	Jun19	Dec19	Jun20	Dec20	Jun21	Dec21	Jun22	Dec22	Jun23	Dec23	Jun24	Dec24	Jun25	Dec25
EBITDA Margin %	Get a 7-Day Free Trial															-1,820.34	-1,975.27	-2,540.26	-7,579.49	1.61

FRA:VSC vs VRTX, REGN, ALNY: EBITDA Margin % Comparison

For the Biotechnology subindustry, 4SC AG's EBITDA Margin %, along with its competitors' market caps and EBITDA Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

4SC AG EBITDA Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, 4SC AG's EBITDA Margin % distribution charts can be found below:

* The bar in red indicates where 4SC AG's EBITDA Margin % falls into.

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4SC AG EBITDA Margin % Calculation

EBITDA margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent.

4SC AG's EBITDA Margin % for the fiscal year that ended in Dec. 2025 is calculated as

EBITDA Margin %	=	EBITDA (A: Dec. 2025 )	/	Revenue (A: Dec. 2025 )
	=	-2.915	/	2.587
	=	-112.68 %

4SC AG's EBITDA Margin % for the quarter that ended in Dec. 2025 is calculated as

EBITDA Margin %	=	EBITDA (Q: Dec. 2025 )	/	Revenue (Q: Dec. 2025 )
	=	0.041	/	2.548
	=	1.61 %

Frequently Asked Questions Learn more about EBITDA Margin % →

What does a EBITDA Margin % of 1.61% mean?

4SC AG (FRA:VSC) has a EBITDA Margin % of 1.61% as of Dec. 2025. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on 4SC AG and its competitors.

Is 4SC AG's EBITDA Margin % too high?

4SC AG's current EBITDA Margin % is 1.61%.

How does 4SC AG's EBITDA Margin % compare to VRTX and REGN?

4SC AG's EBITDA Margin % of 1.61% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.

What is a good EBITDA Margin % for a Biotechnology company?

A good EBITDA Margin % depends on the Biotechnology industry context. However, EBITDA Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.

What does a high EBITDA Margin % mean?

A high EBITDA Margin % can signal that a stock is expensive relative to its fundamentals. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on 4SC AG and its competitors. 4SC AG's current EBITDA Margin % is 1.61%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.

Is 4SC AG stock overvalued right now?

4SC AG (FRA:VSC) has a current EBITDA Margin % of 1.61%. The stock's GF Value™ is €3.51, compared to a current price of €0.10 — trading 97.2% below its estimated fair value. The current EBITDA Margin % is 1.61%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.

How is EBITDA Margin % calculated?

EBITDA Margin % is calculated from a company's financial statements. For 4SC AG (FRA:VSC), the current EBITDA Margin % is 1.61% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

4SC AG Business Description

Industry Healthcare Biotechnology

Comparable Companies FRA:99B0 VRTX REGN ASX:CSL XKRX:207940 ALNY XBRU:UCB XBRU:ARGX INSM ONC XKRX:068270 BNTX OCSE:GMAB INCY HKSE:01801 HKSE:02269 RPRX XKRX:196170 RVMD ROIV

Address Fraunhoferstrasse 22, Planegg-Martinsried, DEU, 82152

Website https://www.4sc.com

4SC AG is a clinical-stage biopharmaceutical company developing small-molecule drugs that can target key indications in cancer with high unmet medical needs. Its pipeline is protected by a comprehensive portfolio of patents and currently comprises two drug candidates in clinical development resminostat and Domatinostat. The geographic area of the company is Germany, the EU, and Other countries, and the majority of the revenue comes from Other Countries.