4SC AGFRA:VSC Return-on-Tangible-Asset is -4.43% as of Dec. 2025. The stock has 7 warning signs investors should review.
Return-on-Tangible-Asset is calculated as Net Income divided by its average total tangible assets. Total tangible assets equals to Total Assets minus Intangible Assets. 4SC AG's annualizedNet Income for the quarter that ended in Dec. 2025 was €-0.36 Mil. 4SC AG's average total tangible assets for the quarter that ended in Dec. 2025 was €8.04 Mil. Therefore, 4SC AG's annualized Return-on-Tangible-Asset for the quarter that ended in Dec. 2025 was -4.43%.
The historical rank and industry rank for 4SC AG's Return-on-Tangible-Asset or its related term are showing as below:
FRA:VSC'
s Return-on-Tangible-Asset Range Over the Past 10 Years
Min: -95.22 Med: -47.42 Max: -27.88
Current: -42.03
During the past 13 years, 4SC AG's highest Return-on-Tangible-Asset was -27.88%. The lowest was -95.22%. And the median was -47.42%.
FRA:VSC's Return-on-Tangible-Asset is not ranked
in the Biotechnology industry.
Industry Median: -35.66
vs FRA:VSC: -42.03
4SC AG (FRA:VSC) Return-on-Tangible-Asset Explanation
Return-on-Tangible-Asset measures the rate of return on the average total tangible assets (total assets minus intangible assets). Tangible means physical in nature. Intangible Assets are assets that are not physical in nature, and typically "derive their value from legal or intellectual rights." Return-on-Tangible-Asset measures a firm's efficiency at generating profits from its tangible assets. It shows how well a company uses what it has to generate earnings. Return-on-Tangible-Assets can vary drastically across industries. Therefore, Return-on-Tangible-Asset should not be used to compare companies in different industries.
Be Aware
Like ROE and ROA, Return-on-Tangible-Asset is calculated with only 12 months data. Fluctuations in the companys earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. Return-on-Tangible-Asset can be affected by events such as stock buyback or issuance, and by a companys tax rate and its interest payment. Return-on-Tangible-Asset may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).
Many analysts argue the higher return the better. Buffett states that really high Return-on-Tangible-Asset may indicate vulnerability in the durability of the competitive advantage.
4SC AG Return-on-Tangible-Asset Related Terms
4SC AG Return-on-Tangible-Asset Historical Data
* Premium members only.
The historical data trend for 4SC AG's Return-on-Tangible-Asset can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
FRA:VSC vs VRTX, REGN, ALNY: Return-on-Tangible-Asset Comparison
For the Biotechnology subindustry, 4SC AG's Return-on-Tangible-Asset, along with its competitors' market caps and Return-on-Tangible-Asset data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
4SC AG Return-on-Tangible-Asset vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, 4SC AG's Return-on-Tangible-Asset distribution charts can be found below:
* The bar in red indicates where 4SC AG's Return-on-Tangible-Asset falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual Return-on-Tangible-Asset, the net income of the last fiscal year and the average total tangible assets over the fiscal year are used. In calculating the quarterly data,
the Net Income data used here is two times the semi-annual (Dec. 2025) net income data.
What does a Return-on-Tangible-Asset of -4.43% mean?
4SC AG (FRA:VSC) has a Return-on-Tangible-Asset of -4.43% as of Dec. 2025. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on 4SC AG and its competitors.
Is 4SC AG's Return-on-Tangible-Asset too high?
4SC AG's current Return-on-Tangible-Asset is -4.43%.
How does 4SC AG's Return-on-Tangible-Asset compare to VRTX and REGN?
4SC AG's Return-on-Tangible-Asset of -4.43% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Asset for a Biotechnology company?
A good Return-on-Tangible-Asset depends on the Biotechnology industry context. However, Return-on-Tangible-Asset should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Asset mean?
A high Return-on-Tangible-Asset can signal that a stock is expensive relative to its fundamentals. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on 4SC AG and its competitors. 4SC AG's current Return-on-Tangible-Asset is -4.43%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is 4SC AG stock overvalued right now?
4SC AG (FRA:VSC) has a current Return-on-Tangible-Asset of -4.43%. The stock's GF Value™ is €3.51, compared to a current price of €0.10 — trading 97.2% below its estimated fair value. The current Return-on-Tangible-Asset is -4.43%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Asset calculated?
Return-on-Tangible-Asset is calculated from a company's financial statements. For 4SC AG (FRA:VSC), the current Return-on-Tangible-Asset is -4.43% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
4SC AG is a clinical-stage biopharmaceutical company developing small-molecule drugs that can target key indications in cancer with high unmet medical needs. Its pipeline is protected by a comprehensive portfolio of patents and currently comprises two drug candidates in clinical development resminostat and Domatinostat. The geographic area of the company is Germany, the EU, and Other countries, and the majority of the revenue comes from Other Countries.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
FRA:VSC has been successfully added to your 