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EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, 4SC AG's enterprise value is €-4.11 Mil.
4SC AG's EBITDA for the trailing twelve months (TTM) ended in Dec. 2025 was €-2.92 Mil. Therefore, 4SC AG's EV-to-EBITDA for today is 1.41.
The historical rank and industry rank for 4SC AG's EV-to-EBITDA or its related term are showing as below:
FRA:VSC'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -16.53 Med: -2.39 Max: 2.5
Current: 1.41
During the past 13 years, the highest EV-to-EBITDA of 4SC AG was 2.50. The lowest was -16.53. And the median was -2.39.
FRA:VSC's EV-to-EBITDA is not ranked
in the Biotechnology industry.
Industry Median: 12.29
vs FRA:VSC: 1.41
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
As of today (2026-07-18), 4SC AG's stock price is €0.10.
4SC AG's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Dec. 2025 was €-0.367. Therefore, 4SC AG's PE Ratio (TTM) for today is At Loss.
The "classic" EV-to-EBITDA is much better in capturing debt and net cash than the PE Ratio (TTM).
4SC AG (FRA:VSC) EV-to-EBITDA Explanation
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
4SC AG's share price for today is €0.10.
For company reported semi-annually, GuruFocus uses latest annual data as the TTM data. 4SC AG's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Dec. 2025 was €-0.367.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
The historical data trend for 4SC AG's EV-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
FRA:VSC vs VRTX, REGN, ALNY: EV-to-EBITDA Comparison
For the Biotechnology subindustry, 4SC AG's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
4SC AG EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, 4SC AG's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where 4SC AG's EV-to-EBITDA falls into.
4SC AG's current Enterprise Value is €-4.11 Mil.
For company reported semi-annually, GuruFocus uses latest annual data as the TTM data. 4SC AG's EBITDA for the trailing twelve months (TTM) ended in Dec. 2025 was €-2.92 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
4SC AG (FRA:VSC) has a EV-to-EBITDA of 1.41 as of Jul. 18, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on 4SC AG.
Is 4SC AG's EV-to-EBITDA too high?
4SC AG's current EV-to-EBITDA is 1.41. The Biotechnology industry median EV-to-EBITDA is 12.29. 4SC AG's value of 1.41 is 88.5% below this industry median.
How does 4SC AG's EV-to-EBITDA compare to VRTX and REGN?
4SC AG's EV-to-EBITDA of 1.41 can be compared against companies in the Biotechnology industry. The industry median EV-to-EBITDA is 12.29. 4SC AG's value of 1.41 is 88.5% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 12.29, based on 398 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. 4SC AG's current EV-to-EBITDA of 1.41 is 88.5% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on 4SC AG. For the Biotechnology industry, the median EV-to-EBITDA is 12.29 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. 4SC AG's current EV-to-EBITDA is 1.41. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is 4SC AG stock overvalued right now?
4SC AG (FRA:VSC) has a current EV-to-EBITDA of 1.41. The stock's GF Value™ is €3.51, compared to a current price of €0.10 — trading 97.2% below its estimated fair value. The current EV-to-EBITDA is 1.41 and 88.5% below the Biotechnology industry median of 12.29. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For 4SC AG (FRA:VSC), the current EV-to-EBITDA is 1.41 as of Jul. 18, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
4SC AG is a clinical-stage biopharmaceutical company developing small-molecule drugs that can target key indications in cancer with high unmet medical needs. Its pipeline is protected by a comprehensive portfolio of patents and currently comprises two drug candidates in clinical development resminostat and Domatinostat. The geographic area of the company is Germany, the EU, and Other countries, and the majority of the revenue comes from Other Countries.
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