Great Novel Therapeutics Biotech & Medicals (ROCO:7427) EBITDA Margin %: -8,455.84% (As of Dec. 2025)


ROCO:7427 Great Novel Therapeutics Biotech & Medicals ROCO:7427
52 GF Score
Price NT$40.15
GF Value NT$25.57
Valuation Significantly Overvalued
! 3 Warning Signs
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What is Great Novel Therapeutics Biotech & Medicals EBITDA Margin %?

Great Novel Therapeutics Biotech & Medicals ROCO:7427 +4.15% 52 EBITDA Margin % is -8,455.84% as of Dec. 2025. GuruFocus rates ROCO:7427 with a GF Score™ of 52/100 and a GF Value™ of NT$25.57 (Significantly Overvalued). The stock has 3 warning signs investors should review. Among 942 Biotechnology companies, Great Novel Therapeutics Biotech & Medicals ranks worse than 92.68% on this metric.

EBITDA Margin % is calculated as EBITDA divided by its Revenue. Great Novel Therapeutics Biotech & Medicals's EBITDA for the six months ended in Dec. 2025 was NT$-49.21 Mil. Great Novel Therapeutics Biotech & Medicals's Revenue for the six months ended in Dec. 2025 was NT$0.58 Mil. Therefore, Great Novel Therapeutics Biotech & Medicals's EBITDA margin for the quarter that ended in Dec. 2025 was -8,455.84%.


Great Novel Therapeutics Biotech & Medicals  (ROCO:7427) EBITDA Margin % Explanation

EBITDA Margin % is the ratio of EBITDA divided by net sales or Revenue. It is an performance metric measuring company's operating profitability. EBITDA Margin takes depreciation and amortization, interest expense and tax into account, which makes it easy to compare the relative profitability of companies of different sizes in the same industry.


Great Novel Therapeutics Biotech & Medicals EBITDA Margin % Related Terms


Great Novel Therapeutics Biotech & Medicals EBITDA Margin % Historical Data

* Premium members only.

The historical data trend for Great Novel Therapeutics Biotech & Medicals's EBITDA Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Great Novel Therapeutics Biotech & Medicals EBITDA Margin % Chart

Great Novel Therapeutics Biotech & Medicals Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EBITDA Margin %
Get a 7-Day Free Trial -5,559.05 -9,992.04 -1,166.27 -5,807.83 -7,443.32

Great Novel Therapeutics Biotech & Medicals Semi-Annual Data
Dec18 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
EBITDA Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -25,234.09 -11,085.58 -3,405.96 -6,497.43 -8,455.84

ROCO:7427 vs VRTX, REGN, ALNY: EBITDA Margin % Comparison

For the Biotechnology subindustry, Great Novel Therapeutics Biotech & Medicals's EBITDA Margin %, along with its competitors' market caps and EBITDA Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Great Novel Therapeutics Biotech & Medicals EBITDA Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Great Novel Therapeutics Biotech & Medicals's EBITDA Margin % distribution charts can be found below:

* The bar in red indicates where Great Novel Therapeutics Biotech & Medicals's EBITDA Margin % falls into.


ROCO:7427
52GF Score
Great Novel Therapeutics Biotech & Medicals ROCO:7427
EBITDA Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Great Novel Therapeutics Biotech & Medicals EBITDA Margin % Calculation

EBITDA margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent.

Great Novel Therapeutics Biotech & Medicals's EBITDA Margin % for the fiscal year that ended in Dec. 2025 is calculated as

EBITDA Margin %=EBITDA (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-89.692/1.205
=-7,443.32 %

Great Novel Therapeutics Biotech & Medicals's EBITDA Margin % for the quarter that ended in Dec. 2025 is calculated as

EBITDA Margin %=EBITDA (Q: Dec. 2025 )/Revenue (Q: Dec. 2025 )
=-49.213/0.582
=-8,455.84 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EBITDA Margin % →
What does a EBITDA Margin % of -8,455.84% mean?
Great Novel Therapeutics Biotech & Medicals (ROCO:7427) has a EBITDA Margin % of -8,455.84% as of Dec. 2025. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Great Novel Therapeutics Biotech & Medicals and its competitors. According to the industry distribution chart, Great Novel Therapeutics Biotech & Medicals ranks #873 out of 942 companies in the Biotechnology industry, placing it in the top 92.7%.
Is Great Novel Therapeutics Biotech & Medicals' EBITDA Margin % too high?
Great Novel Therapeutics Biotech & Medicals' current EBITDA Margin % is -8,455.84%. Based on the distribution chart, Great Novel Therapeutics Biotech & Medicals ranks #873 out of 942 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Great Novel Therapeutics Biotech & Medicals has a GF Score™ of 52/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Great Novel Therapeutics Biotech & Medicals' EBITDA Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Great Novel Therapeutics Biotech & Medicals ranks #873 out of 942 companies for EBITDA Margin %. This places Great Novel Therapeutics Biotech & Medicals in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBITDA Margin % for a Biotechnology company?
A good EBITDA Margin % depends on the Biotechnology industry context. However, EBITDA Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBITDA Margin % mean?
A high EBITDA Margin % can signal that a stock is expensive relative to its fundamentals. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Great Novel Therapeutics Biotech & Medicals and its competitors. Great Novel Therapeutics Biotech & Medicals's current EBITDA Margin % is -8,455.84%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Great Novel Therapeutics Biotech & Medicals stock overvalued right now?
Based on GuruFocus' analysis, Great Novel Therapeutics Biotech & Medicals (ROCO:7427) is currently considered Significantly Overvalued. The stock's GF Value™ is NT$25.57, compared to a current price of NT$40.15 — trading 57% above its estimated fair value. The current EBITDA Margin % is -8,455.84%. Great Novel Therapeutics Biotech & Medicals' overall GF Score™ is 52/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBITDA Margin % calculated?
EBITDA Margin % is calculated from a company's financial statements. For Great Novel Therapeutics Biotech & Medicals (ROCO:7427), the current EBITDA Margin % is -8,455.84% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Great Novel Therapeutics Biotech & Medicals (ROCO:7427) Overvalued in 2026?

Based on GuruFocus' analysis, Great Novel Therapeutics Biotech & Medicals stock appears to be overvalued. The current stock price of NT$40.15 is trading 57% above its estimated GF Value™ of NT$25.57. GuruFocus considers Great Novel Therapeutics Biotech & Medicals to be Significantly Overvalued.

Key valuation signals for ROCO:7427:

  • EBITDA Margin %: -8,455.84%
  • GF Value™: NT$25.57 vs. price of NT$40.15 (57% above fair value)
  • GF Score™: 52/100 with 3 warning signs

No single metric tells the full story. See the ROCO:7427 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Great Novel Therapeutics Biotech & Medicals Business Description

Address No.3, Park Street, Room WR-06, 17th Floor, Nangang District, Taipei, TWN, 11503
Great Novel Therapeutics Biotech & Medicals focuses on drug development to treat advanced cancer. The new drugs ranging from epigenetic modulators, a combination of tumor microenvironment-regulating agents, epigenetic immuno-modulators, to the protein degradation drugs targeting HDACs 1, 2, and 3, are in a developing pipeline. These drugs focus on the field of epigenetics, for the demand of clinical unmet needs in advanced and refractory cancers.
52GF Score

Get the complete analysis for ROCO:7427

EBITDA Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

NT$40.15
Price
NT$25.57
GF Value