Great Novel Therapeutics Biotech & Medicals (ROCO:7427) EBITDA: NT$-89.69 Mil (TTM As of Dec. 2025)


ROCO:7427 Great Novel Therapeutics Biotech & Medicals ROCO:7427
49 GF Score
Price NT$39.65
GF Value NT$25.57
Valuation Significantly Overvalued
! 3 Warning Signs
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What is Great Novel Therapeutics Biotech & Medicals EBITDA?

Great Novel Therapeutics Biotech & Medicals ROCO:7427 -1.25% 49 EBITDA is NT$-89.69 Mil as of Dec. 2025. GuruFocus rates ROCO:7427 with a GF Score™ of 49/100 and a GF Value™ of NT$25.57 (Significantly Overvalued). The stock has 3 warning signs investors should review.

Great Novel Therapeutics Biotech & Medicals's EBITDA for the six months ended in Dec. 2025 was NT$-49.21 Mil. Its EBITDA for the trailing twelve months (TTM) ended in Dec. 2025 was NT$-89.69 Mil.

During the past 3 years, the average EBITDA Growth Rate was -18.50% per year. During the past 5 years, the average EBITDA Growth Rate was -27.80% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the EBITDA Growth Rate using EBITDA data.

During the past 8 years, the highest 3-Year average EBITDA Growth Rate of Great Novel Therapeutics Biotech & Medicals was -0.40% per year. The lowest was -40.90% per year. And the median was -23.30% per year.

Great Novel Therapeutics Biotech & Medicals's EBITDA per Share for the six months ended in Dec. 2025 was NT$-1.09. Its EBITDA per share for the trailing twelve months (TTM) ended in Dec. 2025 was NT$-1.98.

During the past 3 years, the average EBITDA per Share Growth Rate was -2.20% per year. During the past 5 years, the average EBITDA per Share Growth Rate was -7.70% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the EBITDA per share growth rate using EBITDA per Share data.

During the past 8 years, the highest 3-Year average EBITDA per Share Growth Rate of Great Novel Therapeutics Biotech & Medicals was 19.10% per year. The lowest was -19.00% per year. And the median was -2.20% per year.

Great Novel Therapeutics Biotech & Medicals  (ROCO:7427) EBITDA Explanation

EBITDA is a cash flow measure that ignores changes in working capital. EBITDA minus Depreciation, and Amortization (DA) equals Operating Income. Operating Income is profit before interest and taxes. Of course, Interest and taxes need to be paid.

While depreciation and amortization expenses do not need to be paid in cash, assets - especially tangible assets - do need to be replaced over time. EBITDA is not a measure of profit in any sense. EBITDA is a measure of cash generation by a business where the uses of that cash may be more or less discretionary depending on the nature of the business.

The EBITDA of a TV station is largely discretionary. Owners may use much of the EBITDA generated by a TV station as they see fit. The EBITDA of a railroad is largely non-discretionary. Owners must use much of the EBITDA generated by a railroad to replace the physical assets of the railroad or the business will literally fall apart over time.

EBITDA can be thought of as the cash a business generates that is available to:

Add more inventory
Add more receivables
Replace property, plant, and equipment
Add more property, plant, and equipment
Pay interest
Pay taxes
And finally: pay owners

EBITDA is widely used in financial analysis because Depreciation and Amortization are not present day cash expenses.. Depreciation and amortization are the spreading out of the costs of assets over the time in which those assets provide benefits. Today's depreciation and amortization expenses relate to assets bought in the past. The assets being expensed may or may not need to be replaced in the future. And the cost to replace the assets may be more or less than it was in the past. For this reason, the depreciation and amortization expenses a company records in the present year may have no relationship to the actual cash costs needed to maintain its assets in future years.

A company's depreciation expense depends on both its expectations about the assets it owns and its choice of accounting methods. Two companies owning identical assets may have different depreciation expenses because they have different expectations about the useful lives of those assets and because they make different accounting choices.

Analysts use EBITDA to remove this element of personal choice from a company's accounting statements. The use of EBITDA is an attempt to make the results of different companies more comparable and uniform.


Be Aware

Although depreciation is not a cash cost it is a real business cost because the company has to pay for the fixed assets when they purchase them. Both Warren Buffett and Charlie Munger hate the idea of EBITDA because in this calculation, depreciation is not counted as an expense.

EBITDA over Revenue is a good metric for comparing the operating efficiencies between companies because EBITDA is less vulnerable to companies' accounting choices. For this reason, EBITDA is used in ranking the Predictability of Companies. Also Price-to-EBITDA is sometimes used in valuations.


Great Novel Therapeutics Biotech & Medicals EBITDA Related Terms


Great Novel Therapeutics Biotech & Medicals EBITDA Historical Data

* Premium members only.

The historical data trend for Great Novel Therapeutics Biotech & Medicals's EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Great Novel Therapeutics Biotech & Medicals EBITDA Chart

Great Novel Therapeutics Biotech & Medicals Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EBITDA
Get a 7-Day Free Trial -35.02 -53.96 -56.56 -97.86 -89.69

Great Novel Therapeutics Biotech & Medicals Semi-Annual Data
Dec18 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
EBITDA Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -22.21 -58.42 -39.44 -40.48 -49.21

ROCO:7427 vs VRTX, REGN, ALNY: EBITDA Comparison

For the Biotechnology subindustry, Great Novel Therapeutics Biotech & Medicals's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Great Novel Therapeutics Biotech & Medicals EV-to-EBITDA vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Great Novel Therapeutics Biotech & Medicals's EV-to-EBITDA distribution charts can be found below:

* The bar in red indicates where Great Novel Therapeutics Biotech & Medicals's EV-to-EBITDA falls into.


ROCO:7427
49GF Score
Great Novel Therapeutics Biotech & Medicals ROCO:7427
EBITDA is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Earnings Before Interest, Taxes, Depreciation, and Amortization (EBITDA) is what the company earns before it expenses interest, taxes, depreciation and amortization.

Great Novel Therapeutics Biotech & Medicals's EBITDA for the fiscal year that ended in Dec. 2025 is calculated as

Great Novel Therapeutics Biotech & Medicals's EBITDA was directly provided by GuruFocus' data source Morningstar. For the fiscal year ended in Dec. 2025, Great Novel Therapeutics Biotech & Medicals's EBITDA was NT$-89.69 Mil.

Great Novel Therapeutics Biotech & Medicals's EBITDA for the quarter that ended in Dec. 2025 is calculated as

Great Novel Therapeutics Biotech & Medicals's EBITDA was directly provided by GuruFocus' data source Morningstar. For the quarter ended in Dec. 2025, Great Novel Therapeutics Biotech & Medicals's EBITDA was NT$-49.21 Mil.

EBITDA for the trailing twelve months (TTM) ended in Dec. 2025 adds up the semi-annually data reported by the company within the most recent 12 months, which was NT$-89.69 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Sometimes companies may have already deducted Depreciation and Amortization from Gross Profit. In this case Depreciation and Amortization needs to be added back when calculating EBITDA.

Frequently Asked Questions Learn more about EBITDA →
What does a EBITDA of NT$-89.69 Mil mean?
Great Novel Therapeutics Biotech & Medicals (ROCO:7427) has a EBITDA of NT$-89.69 Mil as of Dec. 2025. Ebitda is the difference between operating revenue and operating expenses not including depreciation and amortization. View historical data on Great Novel Therapeutics Biotech & Medicals.
Is Great Novel Therapeutics Biotech & Medicals' EBITDA too high?
Great Novel Therapeutics Biotech & Medicals' current EBITDA is NT$-89.69 Mil. Overall, Great Novel Therapeutics Biotech & Medicals has a GF Score™ of 49/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Great Novel Therapeutics Biotech & Medicals' EBITDA compare to VRTX and REGN?
Great Novel Therapeutics Biotech & Medicals' EBITDA of NT$-89.69 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBITDA for a Biotechnology company?
A good EBITDA depends on the Biotechnology industry context. However, EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBITDA mean?
A high EBITDA can signal that a stock is expensive relative to its fundamentals. Ebitda is the difference between operating revenue and operating expenses not including depreciation and amortization. View historical data on Great Novel Therapeutics Biotech & Medicals. Great Novel Therapeutics Biotech & Medicals's current EBITDA is NT$-89.69 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Great Novel Therapeutics Biotech & Medicals stock overvalued right now?
Based on GuruFocus' analysis, Great Novel Therapeutics Biotech & Medicals (ROCO:7427) is currently considered Significantly Overvalued. The stock's GF Value™ is NT$25.57, compared to a current price of NT$39.65 — trading 55.1% above its estimated fair value. The current EBITDA is NT$-89.69 Mil. Great Novel Therapeutics Biotech & Medicals' overall GF Score™ is 49/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBITDA calculated?
EBITDA is calculated from a company's financial statements. For Great Novel Therapeutics Biotech & Medicals (ROCO:7427), the current EBITDA is NT$-89.69 Mil as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Great Novel Therapeutics Biotech & Medicals (ROCO:7427) Overvalued in 2026?

Based on GuruFocus' analysis, Great Novel Therapeutics Biotech & Medicals stock appears to be overvalued. The current stock price of NT$39.65 is trading 55.1% above its estimated GF Value™ of NT$25.57. GuruFocus considers Great Novel Therapeutics Biotech & Medicals to be Significantly Overvalued.

Key valuation signals for ROCO:7427:

  • EBITDA: NT$-89.69 Mil
  • GF Value™: NT$25.57 vs. price of NT$39.65 (55.1% above fair value)
  • GF Score™: 49/100 with 3 warning signs

No single metric tells the full story. See the ROCO:7427 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Great Novel Therapeutics Biotech & Medicals Business Description

Address No.3, Park Street, Room WR-06, 17th Floor, Nangang District, Taipei, TWN, 11503
Great Novel Therapeutics Biotech & Medicals focuses on drug development to treat advanced cancer. The new drugs ranging from epigenetic modulators, a combination of tumor microenvironment-regulating agents, epigenetic immuno-modulators, to the protein degradation drugs targeting HDACs 1, 2, and 3, are in a developing pipeline. These drugs focus on the field of epigenetics, for the demand of clinical unmet needs in advanced and refractory cancers.
49GF Score

Get the complete analysis for ROCO:7427

EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

NT$39.65
Price
NT$25.57
GF Value