Great Novel Therapeutics Biotech & Medicals (ROCO:7427) 3-Year ROIIC % : 71.96% (As of Dec. 2025) — 12984% Above Median

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ROCO:7427 Great Novel Therapeutics Biotech & Medicals ROCO:7427
40 GF Score
Price NT$72.90
GF Value NT$25.95
Valuation Significantly Overvalued
! 6 Warning Signs
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What is Great Novel Therapeutics Biotech & Medicals 3-Year ROIIC %?

Great Novel Therapeutics Biotech & Medicals ROCO:7427 +6.27% 40 3-Year ROIIC % is 71.96 as of Dec. 2025, which is 12984% above its 10-year median of 0.55. GuruFocus rates ROCO:7427 with a GF Score™ of 40/100 and a GF Value™ of NT$25.95 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 1,315 Biotechnology companies, Great Novel Therapeutics Biotech & Medicals ranks better than 75.59% on this metric.

3-Year Return on Invested Incremental Capital (3-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 3-year. Great Novel Therapeutics Biotech & Medicals's 3-Year ROIIC % for the quarter that ended in Dec. 2025 was 71.96%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

The industry rank for Great Novel Therapeutics Biotech & Medicals's 3-Year ROIIC % or its related term are showing as below:

ROCO:7427's 3-Year ROIIC % is ranked better than
75.59% of 1315 companies
in the Biotechnology industry
Industry Median: -4.44 vs ROCO:7427: 71.96

Great Novel Therapeutics Biotech & Medicals  (ROCO:7427) 3-Year ROIIC % Explanation

Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.

High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

Be Aware

It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.


Great Novel Therapeutics Biotech & Medicals 3-Year ROIIC % Related Terms


Great Novel Therapeutics Biotech & Medicals 3-Year ROIIC % Historical Data

* Premium members only.

The historical data trend for Great Novel Therapeutics Biotech & Medicals's 3-Year ROIIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Great Novel Therapeutics Biotech & Medicals 3-Year ROIIC % Chart

Great Novel Therapeutics Biotech & Medicals Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
3-Year ROIIC %
Get a 7-Day Free Trial 0.55 -45.28 -229.82 128.70 71.96

Great Novel Therapeutics Biotech & Medicals Semi-Annual Data
Dec18 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
3-Year ROIIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -229.82 0.00 128.70 0.00 71.96

ROCO:7427 vs VRTX, REGN, RVMD: 3-Year ROIIC % Comparison

For the Biotechnology subindustry, Great Novel Therapeutics Biotech & Medicals's 3-Year ROIIC %, along with its competitors' market caps and 3-Year ROIIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Great Novel Therapeutics Biotech & Medicals 3-Year ROIIC % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Great Novel Therapeutics Biotech & Medicals's 3-Year ROIIC % distribution charts can be found below:

* The bar in red indicates where Great Novel Therapeutics Biotech & Medicals's 3-Year ROIIC % falls into.


ROCO:7427
40GF Score
Great Novel Therapeutics Biotech & Medicals ROCO:7427
3-Year ROIIC % is just one metric. See GF Score™, valuation, warning signs, and more.
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Great Novel Therapeutics Biotech & Medicals 3-Year ROIIC % Calculation

Great Novel Therapeutics Biotech & Medicals's 3-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:

3-Year ROIIC %=3-Year Incremental Net Operating Profit After Taxes (NOPAT)**/3-Year Incremental Invested Capital**
=( -99.544 (Dec. 2025) - -57.438 (Dec. 2022) )/( 63.88 (Dec. 2025) - 122.395 (Dec. 2022) )
=-42.106/-58.515
=71.96%***

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** Annual data of NOPAT and Invested Capital was used to calculate 3-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.

Frequently Asked Questions Learn more about 3-Year ROIIC % →
What does a 3-Year ROIIC % of 71.96 mean?
Great Novel Therapeutics Biotech & Medicals (ROCO:7427) has a 3-Year ROIIC % of 71.96 as of Dec. 2025. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Great Novel Therapeutics Biotech & Medicals and its competitors. This is 12984% above median its historical median of 0.55. According to the industry distribution chart, Great Novel Therapeutics Biotech & Medicals ranks #321 out of 1315 companies in the Biotechnology industry, placing it in the top 24.4%.
Is Great Novel Therapeutics Biotech & Medicals' 3-Year ROIIC % too high?
Great Novel Therapeutics Biotech & Medicals' current 3-Year ROIIC % of 71.96 is 12984% above median its 10-year median of 0.55. Based on the distribution chart, Great Novel Therapeutics Biotech & Medicals ranks #321 out of 1315 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Great Novel Therapeutics Biotech & Medicals has a GF Score™ of 40/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Great Novel Therapeutics Biotech & Medicals' 3-Year ROIIC % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Great Novel Therapeutics Biotech & Medicals ranks #321 out of 1315 companies for 3-Year ROIIC %. This places Great Novel Therapeutics Biotech & Medicals in the top 24% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year ROIIC % for a Biotechnology company?
A good 3-Year ROIIC % depends on the Biotechnology industry context. However, 3-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year ROIIC % mean?
A high 3-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Great Novel Therapeutics Biotech & Medicals and its competitors. Great Novel Therapeutics Biotech & Medicals's current 3-Year ROIIC % is 71.96, which is 12984% above median its own 10-year median of 0.55. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Great Novel Therapeutics Biotech & Medicals stock overvalued right now?
Based on GuruFocus' analysis, Great Novel Therapeutics Biotech & Medicals (ROCO:7427) is currently considered Significantly Overvalued. The stock's GF Value™ is NT$25.95, compared to a current price of NT$72.90 — trading 180.9% above its estimated fair value. The current 3-Year ROIIC % is 71.96, which is 12984% above median its 10-year median of 0.55. Great Novel Therapeutics Biotech & Medicals' overall GF Score™ is 40/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year ROIIC % calculated?
3-Year ROIIC % is calculated from a company's financial statements. For Great Novel Therapeutics Biotech & Medicals (ROCO:7427), the current 3-Year ROIIC % is 71.96 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Great Novel Therapeutics Biotech & Medicals (ROCO:7427) Overvalued in 2026?

Based on GuruFocus' analysis, Great Novel Therapeutics Biotech & Medicals stock appears to be overvalued. The current stock price of NT$72.90 is trading 180.9% above its estimated GF Value™ of NT$25.95. GuruFocus considers Great Novel Therapeutics Biotech & Medicals to be Significantly Overvalued.

Key valuation signals for ROCO:7427:

  • 3-Year ROIIC %: 71.96 (12984% above median its 10-year median of 0.55)
  • GF Value™: NT$25.95 vs. price of NT$72.90 (180.9% above fair value)
  • GF Score™: 40/100 with 6 warning signs

No single metric tells the full story. See the ROCO:7427 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Great Novel Therapeutics Biotech & Medicals Business Description

Address No.3, Park Street, Room WR-06, 17th Floor, Nangang District, Taipei, TWN, 11503
Great Novel Therapeutics Biotech & Medicals focuses on drug development to treat advanced cancer. The new drugs ranging from epigenetic modulators, a combination of tumor microenvironment-regulating agents, epigenetic immuno-modulators, to the protein degradation drugs targeting HDACs 1, 2, and 3, are in a developing pipeline. These drugs focus on the field of epigenetics, for the demand of clinical unmet needs in advanced and refractory cancers.
40GF Score

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3-Year ROIIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

NT$72.90
Price
NT$25.95
GF Value