Alnylam Pharmaceuticals (LTS:0HD2) Effective Interest Rate on Debt %: 21.72% (As of Mar. 2026)

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LTS:0HD2 Alnylam Pharmaceuticals Inc LTS:0HD2
63 GF Score
Price $275.79
GF Value $526.45
Valuation Significantly Undervalued
! 3 Warning Signs
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What is Alnylam Pharmaceuticals Effective Interest Rate on Debt %?

Alnylam Pharmaceuticals LTS:0HD2 +1.02% 63 Effective Interest Rate on Debt % is 21.72% as of Mar. 2026. GuruFocus rates LTS:0HD2 with a GF Score™ of 63/100 and a GF Value™ of $526.45 (Significantly Undervalued). The stock has 3 warning signs investors should review.

Effective Interest Rate on Debt % is the usage rate that a borrower actually pays on a debt. It is calculated as the positive value of Interest Expense divided by its average total debt. Total debt equals to Long-Term Debt & Capital Lease Obligation plus Short-Term Debt & Capital Lease Obligation. Alnylam Pharmaceuticals's annualized positive value of Interest Expense for the quarter that ended in Mar. 2026 was $277 Mil. Alnylam Pharmaceuticals's average total debt for the quarter that ended in Mar. 2026 was $1,276 Mil. Therefore, Alnylam Pharmaceuticals's annualized Effective Interest Rate on Debt % for the quarter that ended in Mar. 2026 was 21.72%.


Alnylam Pharmaceuticals  (LTS:0HD2) Effective Interest Rate on Debt % Explanation

Effective Interest Rate on Debt % measures the usage rate that a borrower actually pays on a debt.


Alnylam Pharmaceuticals Effective Interest Rate on Debt % Related Terms


Alnylam Pharmaceuticals Effective Interest Rate on Debt % Historical Data

* Premium members only.

The historical data trend for Alnylam Pharmaceuticals's Effective Interest Rate on Debt % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Alnylam Pharmaceuticals Effective Interest Rate on Debt % Chart

Alnylam Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Effective Interest Rate on Debt %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 18.83 13.46 9.23 10.91 19.63

Alnylam Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Effective Interest Rate on Debt % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 17.96 12.39 13.63 40.00 21.72

LTS:0HD2 vs RVMD, ONC, MRNA: Effective Interest Rate on Debt % Comparison

For the Biotechnology subindustry, Alnylam Pharmaceuticals's Effective Interest Rate on Debt %, along with its competitors' market caps and Effective Interest Rate on Debt % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Alnylam Pharmaceuticals Effective Interest Rate on Debt % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Alnylam Pharmaceuticals's Effective Interest Rate on Debt % distribution charts can be found below:

* The bar in red indicates where Alnylam Pharmaceuticals's Effective Interest Rate on Debt % falls into.


LTS:0HD2
63GF Score
Alnylam Pharmaceuticals Inc LTS:0HD2
Effective Interest Rate on Debt % is just one metric. See GF Score™, valuation, warning signs, and more.
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Alnylam Pharmaceuticals Effective Interest Rate on Debt % Calculation

Alnylam Pharmaceuticals's annualized Effective Interest Rate on Debt % for the fiscal year that ended in Dec. 2025 is calculated as

Effective Interest Rate on Debt %
=-1  *  Interest Expense/( (Total Debt  (A: Dec. 2024 )+Total Debt  (A: Dec. 2025 ))/ count )
=-1  *  -252.627/( (1296.048+1278.389)/ 2 )
=-1  *  -252.627/1287.2185
=19.63 %

where

Total Debt  (A: Dec. 2024 )
=Long-Term Debt & Capital Lease Obligation + Short-Term Debt & Capital Lease Obligation
=1254.162 + 41.886
=1296.048

Total Debt  (A: Dec. 2025 )
=Long-Term Debt & Capital Lease Obligation + Short-Term Debt & Capital Lease Obligation
=1232.871 + 45.518
=1278.389

Alnylam Pharmaceuticals's annualized Effective Interest Rate on Debt % for the quarter that ended in Mar. 2026 is calculated as

Effective Interest Rate on Debt %
=-1  *  Interest Expense/( (Total Debt  (Q: Dec. 2025 )+Total Debt  (Q: Mar. 2026 ))/ count )
=-1  *  -277.144/( (1278.389+1273.058)/ 2 )
=-1  *  -277.144/1275.7235
=21.72 %

where

Total Debt  (Q: Dec. 2025 )
=Long-Term Debt & Capital Lease Obligation + Short-Term Debt & Capital Lease Obligation
=1232.871 + 45.518
=1278.389

Total Debt  (Q: Mar. 2026 )
=Long-Term Debt & Capital Lease Obligation + Short-Term Debt & Capital Lease Obligation
=1227.397 + 45.661
=1273.058

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Effective Interest Rate on Debt %, the Interest Expense of the last fiscal year and the average total debt over the fiscal year are used. In calculating the quarterly data, the Interest Expense data used here is four times the quarterly (Mar. 2026) interest expense data. Effective Interest Rate on Debt % is displayed in the 30-year financial page.

What does a Effective Interest Rate on Debt % of 21.72% mean?
Alnylam Pharmaceuticals (LTS:0HD2) has a Effective Interest Rate on Debt % of 21.72% as of Mar. 2026. Effective interest rate on debt is the rate a company actually pays on its debt. View historical data on Alnylam Pharmaceuticals and its competitors.
Is Alnylam Pharmaceuticals' Effective Interest Rate on Debt % too high?
Alnylam Pharmaceuticals' current Effective Interest Rate on Debt % is 21.72%. Overall, Alnylam Pharmaceuticals has a GF Score™ of 63/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Alnylam Pharmaceuticals' Effective Interest Rate on Debt % compare to RVMD and ONC?
Alnylam Pharmaceuticals' Effective Interest Rate on Debt % of 21.72% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Effective Interest Rate on Debt % for a Biotechnology company?
A good Effective Interest Rate on Debt % depends on the Biotechnology industry context. However, Effective Interest Rate on Debt % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Effective Interest Rate on Debt % mean?
A high Effective Interest Rate on Debt % can signal that a stock is expensive relative to its fundamentals. Effective interest rate on debt is the rate a company actually pays on its debt. View historical data on Alnylam Pharmaceuticals and its competitors. Alnylam Pharmaceuticals's current Effective Interest Rate on Debt % is 21.72%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Alnylam Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Alnylam Pharmaceuticals (LTS:0HD2) is currently considered Significantly Undervalued. The stock's GF Value™ is $526.45, compared to a current price of $275.79 — trading 47.6% below its estimated fair value. The current Effective Interest Rate on Debt % is 21.72%. Alnylam Pharmaceuticals' overall GF Score™ is 63/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Effective Interest Rate on Debt % calculated?
Effective Interest Rate on Debt % is calculated from a company's financial statements. For Alnylam Pharmaceuticals (LTS:0HD2), the current Effective Interest Rate on Debt % is 21.72% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Alnylam Pharmaceuticals (LTS:0HD2) Overvalued in 2026?

Based on GuruFocus' analysis, Alnylam Pharmaceuticals stock appears to be undervalued. The current stock price of $275.79 is trading 47.6% below its estimated GF Value™ of $526.45. GuruFocus considers Alnylam Pharmaceuticals to be Significantly Undervalued.

Key valuation signals for LTS:0HD2:

  • Effective Interest Rate on Debt %: 21.72%
  • GF Value™: $526.45 vs. price of $275.79 (47.6% below fair value)
  • GF Score™: 63/100 with 3 warning signs

No single metric tells the full story. See the LTS:0HD2 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Alnylam Pharmaceuticals Business Description

Address 675 West Kendall Street, Henri A. Termeer Square, Cambridge, MA, USA, 02142
Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam's commercial RNAi therapeutic products include Onpattro and Amvuttra (for hATTR amyloidosis), Givlaari (for acute hepatic porphyria), and Oxlumo (for primary hyperoxaluria type 1), all developed and commercialized by Alnylam. Plus, Leqvio (for hypercholesterolemia) and Qfitlia (for hemophilia A or B), which are being commercialized by Alnylam's partners, Novartis and Sanofi, respectively. It also has several clinical programs across various therapeutic areas, including cardio-metabolic diseases, neuroscience, and hematology.
63GF Score

Get the complete analysis for LTS:0HD2

Effective Interest Rate on Debt % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$275.79
Price
$526.45
GF Value