Alnylam Pharmaceuticals (LTS:0HD2) OCF Yield %: 1.82 (As of Jun. 30, 2026)


LTS:0HD2 Alnylam Pharmaceuticals Inc LTS:0HD2
67 GF Score
Price $294.38
GF Value $515.25
Valuation Significantly Undervalued
! 3 Warning Signs
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What is Alnylam Pharmaceuticals OCF Yield %?

Alnylam Pharmaceuticals LTS:0HD2 67 OCF Yield % is 1.82 as of Jun. 30, 2026. GuruFocus rates LTS:0HD2 with a GF Score™ of 67/100 and a GF Value™ of $515.25 (Significantly Undervalued). The stock has 3 warning signs investors should review. Among 1,416 Biotechnology companies, Alnylam Pharmaceuticals ranks better than 83.19% on this metric.

OCF Yield % is calculated as Cash Flow from Operations divided by Market Capitalization. It is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

As of today, Alnylam Pharmaceuticals's Trailing 12-Month Cash Flow from Operations is $715 Mil, and Market Cap is $39,189 Mil. Therefore, Alnylam Pharmaceuticals's OCF Yield % for today is 1.82%.

The historical rank and industry rank for Alnylam Pharmaceuticals's OCF Yield % or its related term are showing as below:

LTS:0HD2' s OCF Yield % Range Over the Past 10 Years
Min: -9.76   Med: -2.62   Max: 1.86
Current: 1.82


During the past 13 years, the highest OCF Yield % of Alnylam Pharmaceuticals was 1.86%. The lowest was -9.76%. And the median was -2.62%.

LTS:0HD2's OCF Yield % is ranked better than
83.19% of 1416 companies
in the Biotechnology industry
Industry Median: -8.185 vs LTS:0HD2: 1.82

Alnylam Pharmaceuticals's OCF Margin % for the quarter that ended in Mar. 2026 was %.


Alnylam Pharmaceuticals OCF Yield % Explanation

Similar to Earnings Yield %, OCF Yield % is financial solvency ratio. A lower ratio suggests a less attractive investment, indicating that investors might not receive substantial returns in proportion to their investment. Conversely, a high operating cash flow yield signals that a company generates sufficient cash to comfortably meet its debts, obligations, and dividend payments, making it a promising investment choice.


Alnylam Pharmaceuticals OCF Yield % Related Terms


Alnylam Pharmaceuticals OCF Yield % Historical Data

* Premium members only.

The historical data trend for Alnylam Pharmaceuticals's OCF Yield % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Alnylam Pharmaceuticals OCF Yield % Chart

Alnylam Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
OCF Yield %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -2.69 -1.89 0.43 -0.03 0.98

Alnylam Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
OCF Yield % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1.39 1.46 2.17 1.23 0.64

LTS:0HD2 vs RVMD, ONC, MRNA: OCF Yield % Comparison

For the Biotechnology subindustry, Alnylam Pharmaceuticals's OCF Yield %, along with its competitors' market caps and OCF Yield % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Alnylam Pharmaceuticals OCF Yield % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Alnylam Pharmaceuticals's OCF Yield % distribution charts can be found below:

* The bar in red indicates where Alnylam Pharmaceuticals's OCF Yield % falls into.


LTS:0HD2
67GF Score
Alnylam Pharmaceuticals Inc LTS:0HD2
OCF Yield % is just one metric. See GF Score™, valuation, warning signs, and more.
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Alnylam Pharmaceuticals OCF Yield % Calculation

OCF Yield % is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

Alnylam Pharmaceuticals's OCF Yield % for the fiscal year that ended in Dec. 2025 is calculated as

OCF Yield %=Cash Flow from Operations / Market Cap
=524.08 / 53246.8031016
=0.98%

Alnylam Pharmaceuticals's annualized OCF Yield % for the quarter that ended in Mar. 2026 is calculated as

OCF Yield %=Cash Flow from Operations * Annualized Factor / Market Cap
=70.504 * 4 / 43896.4038
=0.64%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Yield % →
What does a OCF Yield % of 1.82 mean?
Alnylam Pharmaceuticals (LTS:0HD2) has a OCF Yield % of 1.82 as of Jun. 30, 2026. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Alnylam Pharmaceuticals and its competitors. According to the industry distribution chart, Alnylam Pharmaceuticals ranks #238 out of 1416 companies in the Biotechnology industry, placing it in the top 16.8%.
Is Alnylam Pharmaceuticals' OCF Yield % too high?
Alnylam Pharmaceuticals' current OCF Yield % is 1.82. Based on the distribution chart, Alnylam Pharmaceuticals ranks #238 out of 1416 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Alnylam Pharmaceuticals has a GF Score™ of 67/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Alnylam Pharmaceuticals' OCF Yield % compare to RVMD and ONC?
According to the Biotechnology industry distribution chart, Alnylam Pharmaceuticals ranks #238 out of 1416 companies for OCF Yield %. This places Alnylam Pharmaceuticals in the top 17% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Yield % for a Biotechnology company?
A good OCF Yield % depends on the Biotechnology industry context. However, OCF Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Yield % mean?
A high OCF Yield % can signal that a stock is expensive relative to its fundamentals. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Alnylam Pharmaceuticals and its competitors. Alnylam Pharmaceuticals's current OCF Yield % is 1.82. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Alnylam Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Alnylam Pharmaceuticals (LTS:0HD2) is currently considered Significantly Undervalued. The stock's GF Value™ is $515.25, compared to a current price of $294.38 — trading 42.9% below its estimated fair value. The current OCF Yield % is 1.82. Alnylam Pharmaceuticals' overall GF Score™ is 67/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Yield % calculated?
OCF Yield % is calculated from a company's financial statements. For Alnylam Pharmaceuticals (LTS:0HD2), the current OCF Yield % is 1.82 as of Jun. 30, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Alnylam Pharmaceuticals (LTS:0HD2) Overvalued in 2026?

Based on GuruFocus' analysis, Alnylam Pharmaceuticals stock appears to be undervalued. The current stock price of $294.38 is trading 42.9% below its estimated GF Value™ of $515.25. GuruFocus considers Alnylam Pharmaceuticals to be Significantly Undervalued.

Key valuation signals for LTS:0HD2:

  • OCF Yield %: 1.82
  • GF Value™: $515.25 vs. price of $294.38 (42.9% below fair value)
  • GF Score™: 67/100 with 3 warning signs

No single metric tells the full story. See the LTS:0HD2 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Alnylam Pharmaceuticals Business Description

Address 675 West Kendall Street, Henri A. Termeer Square, Cambridge, MA, USA, 02142
Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam's commercial RNAi therapeutic products include Onpattro and Amvuttra (for hATTR amyloidosis), Givlaari (for acute hepatic porphyria), and Oxlumo (for primary hyperoxaluria type 1), all developed and commercialized by Alnylam. Plus, Leqvio (for hypercholesterolemia) and Qfitlia (for hemophilia A or B), which are being commercialized by Alnylam's partners, Novartis and Sanofi, respectively. It also has several clinical programs across various therapeutic areas, including cardio-metabolic diseases, neuroscience, and hematology.
67GF Score

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OCF Yield % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$294.38
Price
$515.25
GF Value