Alnylam Pharmaceuticals (LTS:0HD2) Net-Net Working Capital: $-1.22 (As of Jun. 2026)

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LTS:0HD2 Alnylam Pharmaceuticals Inc LTS:0HD2
68 GF Score
Price $215.17
GF Value $519.17
Valuation Significantly Undervalued
! 2 Warning Signs
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What is Alnylam Pharmaceuticals Net-Net Working Capital?

Alnylam Pharmaceuticals LTS:0HD2 -2.27% 68 Net-Net Working Capital is $-1.22 as of Jun. 2026. GuruFocus rates LTS:0HD2 with a GF Score™ of 68/100 and a GF Value™ of $519.17 (Significantly Undervalued). The stock has 2 warning signs investors should review. Among 856 Biotechnology companies, Alnylam Pharmaceuticals ranks worse than 116822.31% on this metric.

In calculating the Net-Net Working Capital (NNWC), Benjamin Graham assumed that a company's accounts receivable is only worth 75% its value, its inventory is only worth 50% of its value, but its liabilities have to be paid in full. In addition, Graham believed that preferred stock belongs on the liability side of the balance sheet, not as part of capital and surplus. This is a conservative way of estimating the company's value.

Alnylam Pharmaceuticals's Net-Net Working Capital for the quarter that ended in Jun. 2026 was $-1.22.

The industry rank for Alnylam Pharmaceuticals's Net-Net Working Capital or its related term are showing as below:

LTS:0HD2's Price-to-Net-Net-Working-Capital is not ranked *
in the Biotechnology industry.
Industry Median: 5.46
* Ranked among companies with meaningful Price-to-Net-Net-Working-Capital only.

Alnylam Pharmaceuticals  (LTS:0HD2) Net-Net Working Capital Explanation

One research study, covering the years 1970 through 1983 showed that portfolios picked at the beginning of each year, and held for one year, returned 29.4 percent, on average, over the 13-year period, compared to 11.5 percent for the S&P 500 Index. Other studies of Graham's strategy produced similar results.

Benjamin Graham looked for companies whose market values were less than two-thirds of their net-net value. They are collected under our Net-Net screener.


Alnylam Pharmaceuticals Net-Net Working Capital Related Terms


Alnylam Pharmaceuticals Net-Net Working Capital Historical Data

* Premium members only.

The historical data trend for Alnylam Pharmaceuticals's Net-Net Working Capital can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Alnylam Pharmaceuticals Net-Net Working Capital Chart

Alnylam Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Net-Net Working Capital
Get a 7-Day Free Trial Premium Member Only Premium Member Only -3.56 -10.24 -10.50 -8.78 -4.87

Alnylam Pharmaceuticals Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Net-Net Working Capital Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -7.61 -8.59 -4.87 -2.55 -1.22

LTS:0HD2 vs ONC, RVMD, RPRX: Net-Net Working Capital Comparison

For the Biotechnology subindustry, Alnylam Pharmaceuticals's Price-to-Net-Net-Working-Capital, along with its competitors' market caps and Price-to-Net-Net-Working-Capital data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Alnylam Pharmaceuticals Price-to-Net-Net-Working-Capital vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Alnylam Pharmaceuticals's Price-to-Net-Net-Working-Capital distribution charts can be found below:

* The bar in red indicates where Alnylam Pharmaceuticals's Price-to-Net-Net-Working-Capital falls into.


LTS:0HD2
68GF Score
Alnylam Pharmaceuticals Inc LTS:0HD2
Net-Net Working Capital is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Alnylam Pharmaceuticals Net-Net Working Capital Calculation

Alnylam Pharmaceuticals's Net-Net Working Capital (NNWC) per share for the fiscal year that ended in Dec. 2025 is calculated as

Net-Net Working Capital(A: Dec. 2025 )
=(Cash, Cash Equivalents, Marketable Securities+0.75 * Accounts Receivable+0.5 * Total Inventories-Total Liabilities
-Preferred Stock-Minority Interest)/Shares Outstanding (EOP)
=(2908.484+0.75 * 777.567+0.5 * 82.719-4177.155
-0-0)/132.376
=-4.87

Alnylam Pharmaceuticals's Net-Net Working Capital (NNWC) per share for the quarter that ended in Jun. 2026 is calculated as

Net-Net Working Capital(Q: Jun. 2026 )
=(Cash, Cash Equivalents, Marketable Securities+0.75 * Accounts Receivable+0.5 * Total Inventories-Total Liabilities
-Preferred Stock-Minority Interest)/Shares Outstanding (EOP)
=(3308.147+0.75 * 912.739+0.5 * 97.11-4204.651
-0-0)/133.734
=-1.22

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In calculating the Net-Net Working Capital (NNWC), Benjamin Graham assumed that a company's accounts receivable is only worth 75% its value, its inventory is only worth 50% of its value, but its liabilities have to be paid in full.

In addition, Graham believed that preferred stock belongs on the liability side of the balance sheet, not as part of capital and surplus. In "Security Analysis", preferred stock is dubbed "an imperfect creditorship position" that is best placed on the balance sheet alongside funded debt.

This is a conservative way of estimating the company's value.

What does a Net-Net Working Capital of $-1.22 mean?
Alnylam Pharmaceuticals (LTS:0HD2) has a Net-Net Working Capital of $-1.22 as of Jun. 2026. Ben Graham defined net-net working capital as the per-share sum of cash, 75% of receivables and 50% of inventory less total liabilities. View historical data on Alnylam Pharmaceuticals According to the industry distribution chart, Alnylam Pharmaceuticals ranks #999999 out of 856 companies in the Biotechnology industry.
Is Alnylam Pharmaceuticals' Net-Net Working Capital too high?
Alnylam Pharmaceuticals' current Net-Net Working Capital is $-1.22. Based on the distribution chart, Alnylam Pharmaceuticals ranks #999999 out of 856 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Alnylam Pharmaceuticals has a GF Score™ of 68/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Alnylam Pharmaceuticals' Net-Net Working Capital compare to ONC and RVMD?
According to the Biotechnology industry distribution chart, Alnylam Pharmaceuticals ranks #999999 out of 856 companies for Net-Net Working Capital. This places Alnylam Pharmaceuticals in the lower half of its industry. The industry median Net-Net Working Capital is 5.46. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net-Net Working Capital for a Biotechnology company?
The median Net-Net Working Capital among Biotechnology companies is 5.46, based on 856 companies in the industry. Companies in the top quartile (top 25%) have a Net-Net Working Capital significantly above this median, while those in the bottom quartile fall well below. However, Net-Net Working Capital should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net-Net Working Capital mean?
A high Net-Net Working Capital can signal that a stock is expensive relative to its fundamentals. Ben Graham defined net-net working capital as the per-share sum of cash, 75% of receivables and 50% of inventory less total liabilities. View historical data on Alnylam Pharmaceuticals For the Biotechnology industry, the median Net-Net Working Capital is 5.46 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Alnylam Pharmaceuticals's current Net-Net Working Capital is $-1.22. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Alnylam Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Alnylam Pharmaceuticals (LTS:0HD2) is currently considered Significantly Undervalued. The stock's GF Value™ is $519.17, compared to a current price of $215.17 — trading 58.6% below its estimated fair value. The current Net-Net Working Capital is $-1.22. Alnylam Pharmaceuticals' overall GF Score™ is 68/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net-Net Working Capital calculated?
Net-Net Working Capital is calculated from a company's financial statements. For Alnylam Pharmaceuticals (LTS:0HD2), the current Net-Net Working Capital is $-1.22 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Alnylam Pharmaceuticals (LTS:0HD2) Overvalued in 2026?

Based on GuruFocus' analysis, Alnylam Pharmaceuticals stock appears to be undervalued. The current stock price of $215.17 is trading 58.6% below its estimated GF Value™ of $519.17. GuruFocus considers Alnylam Pharmaceuticals to be Significantly Undervalued.

Key valuation signals for LTS:0HD2:

  • Net-Net Working Capital: $-1.22
  • GF Value™: $519.17 vs. price of $215.17 (58.6% below fair value)
  • GF Score™: 68/100 with 2 warning signs

No single metric tells the full story. See the LTS:0HD2 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Alnylam Pharmaceuticals Business Description

Address 675 West Kendall Street, Henri A. Termeer Square, Cambridge, MA, USA, 02142
Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam's commercial RNAi therapeutic products include Onpattro and Amvuttra (for hATTR amyloidosis), Givlaari (for acute hepatic porphyria), and Oxlumo (for primary hyperoxaluria type 1), all developed and commercialized by Alnylam. Plus, Leqvio (for hypercholesterolemia) and Qfitlia (for hemophilia A or B), which are being commercialized by Alnylam's partners, Novartis and Sanofi, respectively. It also has several clinical programs across various therapeutic areas, including cardio-metabolic diseases, neuroscience, and hematology.
68GF Score

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Net-Net Working Capital is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$215.17
Price
$519.17
GF Value