TWST (Twist Bioscience) EV-to-EBIT: -51.24 (As of Aug. 07, 2026)

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TWST Twist Bioscience Corp TWST
69 GF Score
Price $113.91
GF Value $52.17
Valuation Significantly Overvalued
! 5 Warning Signs
View Full Analysis

What is Twist Bioscience EV-to-EBIT?

Twist Bioscience TWST +4.43% 69 EV-to-EBIT is -51.24 as of Aug. 07, 2026. GuruFocus rates TWST with a GF Score™ of 69/100 and a GF Value™ of $52.17 (Significantly Overvalued). The stock has 5 warning signs investors should review. Among 105 Medical Diagnostics & Research companies, Twist Bioscience ranks worse than 952380% on this metric.

EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, Twist Bioscience's Enterprise Value is $7,069.8 Mil. Twist Bioscience's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 was $-138.0 Mil. Therefore, Twist Bioscience's EV-to-EBIT for today is -51.24.

The historical rank and industry rank for Twist Bioscience's EV-to-EBIT or its related term are showing as below:

TWST' s EV-to-EBIT Range Over the Past 10 Years
Min: -70.74   Med: -10.73   Max: -1.8
Current: -51.24

During the past 10 years, the highest EV-to-EBIT of Twist Bioscience was -1.80. The lowest was -70.74. And the median was -10.73.

TWST's EV-to-EBIT is ranked worse than
100% of 105 companies
in the Medical Diagnostics & Research industry
Industry Median: 23.62 vs TWST: -51.24

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %. Twist Bioscience's Enterprise Value for the quarter that ended in Jun. 2026 was $6,374.7 Mil. Twist Bioscience's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 was $-138.0 Mil. Twist Bioscience's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Jun. 2026 was -2.16%.


Twist Bioscience  (NAS:TWST) EV-to-EBIT Explanation

This is a more accurate valuation of companies' operation because it considers the debt and cash on its balance sheet, and non-operating items such as interest payment, tax, and one-time items are not included in the Operating Income.

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %.

Twist Bioscience's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Jun. 2026 is calculated as:

Earnings Yield (Joel Greenblatt) % (Q: Jun. 2026 ) =EBIT / Enterprise Value (Q: Jun. 2026 )
=-137.972/6374.65212
=-2.16 %

Twist Bioscience's Enterprise Value for the quarter that ended in Jun. 2026 was $6,374.7 Mil.
Twist Bioscience's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-138.0 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Twist Bioscience EV-to-EBIT Related Terms


Twist Bioscience EV-to-EBIT Historical Data

* Premium members only.

The historical data trend for Twist Bioscience's EV-to-EBIT can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Twist Bioscience EV-to-EBIT Chart

Twist Bioscience Annual Data
Trend Sep16 Sep17 Sep18 Sep19 Sep20 Sep21 Sep22 Sep23 Sep24 Sep25
EV-to-EBIT
Get a 7-Day Free Trial Premium Member Only Premium Member Only -31.76 -6.93 -4.46 -14.03 -11.37

Twist Bioscience Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
EV-to-EBIT Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -14.34 -11.37 -13.69 -21.83 -46.20

TWST vs BLLN, SHC, RDNT: EV-to-EBIT Comparison

For the Diagnostics & Research subindustry, Twist Bioscience's EV-to-EBIT, along with its competitors' market caps and EV-to-EBIT data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Twist Bioscience EV-to-EBIT vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Twist Bioscience's EV-to-EBIT distribution charts can be found below:

* The bar in red indicates where Twist Bioscience's EV-to-EBIT falls into.


TWST
69GF Score
Twist Bioscience Corp TWST
EV-to-EBIT is just one metric. See GF Score™, valuation, warning signs, and more.
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Twist Bioscience EV-to-EBIT Calculation

Twist Bioscience's EV-to-EBIT for today is calculated as:

EV-to-EBIT=Enterprise Value (Today)/EBIT (TTM)
=7069.754/-137.972
=-51.24

Twist Bioscience's current Enterprise Value is $7,069.8 Mil.
Twist Bioscience's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-138.0 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBIT →
What does a EV-to-EBIT of -51.24 mean?
Twist Bioscience (TWST) has a EV-to-EBIT of -51.24 as of Aug. 07, 2026. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Twist Bioscience and its competitors. According to the industry distribution chart, Twist Bioscience ranks #999999 out of 105 companies in the Medical Diagnostics & Research industry.
Is Twist Bioscience's EV-to-EBIT too high?
Twist Bioscience's current EV-to-EBIT is -51.24. Based on the distribution chart, Twist Bioscience ranks #999999 out of 105 companies in the Medical Diagnostics & Research industry, which is in the bottom quartile relative to peers. Overall, Twist Bioscience has a GF Score™ of 69/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Twist Bioscience's EV-to-EBIT compare to BLLN and SHC?
According to the Medical Diagnostics & Research industry distribution chart, Twist Bioscience ranks #999999 out of 105 companies for EV-to-EBIT. This places Twist Bioscience in the lower half of its industry. The industry median EV-to-EBIT is 23.62. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBIT for a Medical Diagnostics & Research company?
The median EV-to-EBIT among Medical Diagnostics & Research companies is 23.62, based on 105 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBIT significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBIT should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBIT mean?
A high EV-to-EBIT can signal that a stock is expensive relative to its fundamentals. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Twist Bioscience and its competitors. For the Medical Diagnostics & Research industry, the median EV-to-EBIT is 23.62 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Twist Bioscience's current EV-to-EBIT is -51.24. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Twist Bioscience stock overvalued right now?
Based on GuruFocus' analysis, Twist Bioscience (TWST) is currently considered Significantly Overvalued. The stock's GF Value™ is $52.17, compared to a current price of $113.91 — trading 118.3% above its estimated fair value. The current EV-to-EBIT is -51.24. Twist Bioscience's overall GF Score™ is 69/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBIT calculated?
EV-to-EBIT is calculated from a company's financial statements. For Twist Bioscience (TWST), the current EV-to-EBIT is -51.24 as of Aug. 07, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Twist Bioscience (TWST) Overvalued in 2026?

Based on GuruFocus' analysis, Twist Bioscience stock appears to be overvalued. The current stock price of $113.91 is trading 118.3% above its estimated GF Value™ of $52.17. GuruFocus considers Twist Bioscience to be Significantly Overvalued.

Key valuation signals for TWST:

  • EV-to-EBIT: -51.24
  • GF Value™: $52.17 vs. price of $113.91 (118.3% above fair value)
  • GF Score™: 69/100 with 5 warning signs

No single metric tells the full story. See the TWST stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Twist Bioscience Business Description

Other Exchanges 1TWST:Italy0ME:Germany
Address 681 Gateway Boulevard, South San Francisco, CA, USA, 94080
Twist Bioscience Corp is a synthetic biology company that has developed a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's proprietary semiconductor-based manufacturing process synthesizes DNA on silicon rather than traditional plastic plates, enabling the production of high-quality synthetic DNA faster, more affordably, and at scale. This platform overcomes conventional inefficiencies, supports cost-effective, high-throughput synthesis, and allows researchers to accelerate innovation. Geographically, the company operates across the Americas, EMEA, and APAC, deriving the majority of its revenue from the Americas.
69GF Score

Get the complete analysis for TWST

EV-to-EBIT is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$113.91
Price
$52.17
GF Value