TWST (Twist Bioscience) OCF Margin %: 0.94% (As of Jun. 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

TWST Twist Bioscience Corp TWST
69 GF Score
Price $115.84
GF Value $52.17
Valuation Significantly Overvalued
! 5 Warning Signs
View Full Analysis

What is Twist Bioscience OCF Margin %?

Twist Bioscience TWST +6.20% 69 OCF Margin % is 0.94% as of Jun. 2026. GuruFocus rates TWST with a GF Score™ of 69/100 and a GF Value™ of $52.17 (Significantly Overvalued). The stock has 5 warning signs investors should review. Among 203 Medical Diagnostics & Research companies, Twist Bioscience ranks worse than 68.47% on this metric.

OCF Margin % is calculated as Cash Flow from Operations divided by its Revenue. Twist Bioscience's Cash Flow from Operations for the three months ended in Jun. 2026 was $1.1 Mil. Twist Bioscience's Revenue for the three months ended in Jun. 2026 was $118.4 Mil. Therefore, Twist Bioscience's OCF Margin % for the quarter that ended in Jun. 2026 was 0.94%.

As of today, Twist Bioscience's current OCF Yield % is -0.73%.

The historical rank and industry rank for Twist Bioscience's OCF Margin % or its related term are showing as below:

TWST' s OCF Margin % Range Over the Past 10 Years
Min: -1700.84   Med: -121.36   Max: -12.65
Current: -12.29


During the past 10 years, the highest OCF Margin % of Twist Bioscience was -12.65%. The lowest was -1700.84%. And the median was -121.36%.

TWST's OCF Margin % is ranked worse than
68.47% of 203 companies
in the Medical Diagnostics & Research industry
Industry Median: 5.53 vs TWST: -12.29


Twist Bioscience OCF Margin % Related Terms


Twist Bioscience OCF Margin % Historical Data

* Premium members only.

The historical data trend for Twist Bioscience's OCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Twist Bioscience OCF Margin % Chart

Twist Bioscience Annual Data
Trend Sep16 Sep17 Sep18 Sep19 Sep20 Sep21 Sep22 Sep23 Sep24 Sep25
OCF Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -84.82 -61.10 -58.13 -20.48 -12.65

Twist Bioscience Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
OCF Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1.46 -11.93 -23.93 -15.86 0.94

TWST vs BLLN, SHC, RDNT: OCF Margin % Comparison

For the Diagnostics & Research subindustry, Twist Bioscience's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Twist Bioscience OCF Margin % vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Twist Bioscience's OCF Margin % distribution charts can be found below:

* The bar in red indicates where Twist Bioscience's OCF Margin % falls into.


TWST
69GF Score
Twist Bioscience Corp TWST
OCF Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Twist Bioscience OCF Margin % Calculation

OCF Margin % is the ratio of Cash Flow from Operations divided by net sales or Revenue, usually presented in percent.

Twist Bioscience's OCF Margin for the fiscal year that ended in Sep. 2025 is calculated as

OCF Margin=Cash Flow from Operations (A: Sep. 2025 )/Revenue (A: Sep. 2025 )
=-47.628/376.572
=-12.65 %

Twist Bioscience's OCF Margin for the quarter that ended in Jun. 2026 is calculated as

OCF Margin=Cash Flow from Operations (Q: Jun. 2026 )/Revenue (Q: Jun. 2026 )
=1.115/118.376
=0.94 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Margin % →
What does a OCF Margin % of 0.94% mean?
Twist Bioscience (TWST) has a OCF Margin % of 0.94% as of Jun. 2026. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Twist Bioscience and its competitors. According to the industry distribution chart, Twist Bioscience ranks #139 out of 203 companies in the Medical Diagnostics & Research industry, placing it in the top 68.5%.
Is Twist Bioscience's OCF Margin % too high?
Twist Bioscience's current OCF Margin % is 0.94%. The Medical Diagnostics & Research industry median OCF Margin % is 5.53. Twist Bioscience's value of 0.94% is 83% below this industry median. Based on the distribution chart, Twist Bioscience ranks #139 out of 203 companies in the Medical Diagnostics & Research industry, which is below the industry midpoint. Overall, Twist Bioscience has a GF Score™ of 69/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Twist Bioscience's OCF Margin % compare to BLLN and SHC?
According to the Medical Diagnostics & Research industry distribution chart, Twist Bioscience ranks #139 out of 203 companies for OCF Margin %. This places Twist Bioscience in the lower half of its industry. The industry median OCF Margin % is 5.53. Twist Bioscience's value of 0.94% is 83% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Margin % for a Medical Diagnostics & Research company?
The median OCF Margin % among Medical Diagnostics & Research companies is 5.53, based on 203 companies in the industry. Companies in the top quartile (top 25%) have a OCF Margin % significantly above this median, while those in the bottom quartile fall well below. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Twist Bioscience's current OCF Margin % of 0.94% is 83% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Margin % mean?
A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Twist Bioscience and its competitors. For the Medical Diagnostics & Research industry, the median OCF Margin % is 5.53 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Twist Bioscience's current OCF Margin % is 0.94%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Twist Bioscience stock overvalued right now?
Based on GuruFocus' analysis, Twist Bioscience (TWST) is currently considered Significantly Overvalued. The stock's GF Value™ is $52.17, compared to a current price of $115.84 — trading 122% above its estimated fair value. The current OCF Margin % is 0.94% and 83% below the Medical Diagnostics & Research industry median of 5.53. Twist Bioscience's overall GF Score™ is 69/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Margin % calculated?
OCF Margin % is calculated from a company's financial statements. For Twist Bioscience (TWST), the current OCF Margin % is 0.94% as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Twist Bioscience (TWST) Overvalued in 2026?

Based on GuruFocus' analysis, Twist Bioscience stock appears to be overvalued. The current stock price of $115.84 is trading 122% above its estimated GF Value™ of $52.17. GuruFocus considers Twist Bioscience to be Significantly Overvalued.

Key valuation signals for TWST:

  • OCF Margin %: 0.94%
  • GF Value™: $52.17 vs. price of $115.84 (122% above fair value)
  • GF Score™: 69/100 with 5 warning signs
  • Industry Position: 83% below the Medical Diagnostics & Research median (#139 of 203)

No single metric tells the full story. See the TWST stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Twist Bioscience Business Description

Other Exchanges 1TWST:Italy0ME:Germany
Address 681 Gateway Boulevard, South San Francisco, CA, USA, 94080
Twist Bioscience Corp is a synthetic biology company that has developed a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's proprietary semiconductor-based manufacturing process synthesizes DNA on silicon rather than traditional plastic plates, enabling the production of high-quality synthetic DNA faster, more affordably, and at scale. This platform overcomes conventional inefficiencies, supports cost-effective, high-throughput synthesis, and allows researchers to accelerate innovation. Geographically, the company operates across the Americas, EMEA, and APAC, deriving the majority of its revenue from the Americas.
69GF Score

Get the complete analysis for TWST

OCF Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$115.84
Price
$52.17
GF Value