TWST (Twist Bioscience) Shares Buyback Ratio %: -4.15 (As of Sep. 13, 2026)

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TWST Twist Bioscience Corp TWST
64 GF Score
Price $127.07
GF Value $53.22
Valuation Significantly Overvalued
! 2 Warning Signs
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What is Twist Bioscience Shares Buyback Ratio %?

Twist Bioscience TWST +0.29% 64 Shares Buyback Ratio % is -4.15 as of Sep. 13, 2026. GuruFocus rates TWST with a GF Score™ of 64/100 and a GF Value™ of $53.22 (Significantly Overvalued). The stock has 2 warning signs investors should review.

Shares Outstanding (EOP) are shares that have been authorized, issued, and purchased by investors and are held by them.

GuruFocus calculates shares buyback ratio using previous shares outstanding minus the current shares outstanding, and then divides by previous shares outstanding. Twist Bioscience's current shares buyback ratio was -4.15%.

Twist Bioscience Shares Buyback Ratio % Related Terms

Twist Bioscience Shares Buyback Ratio % Historical Data

* Premium members only.

The historical data trend for Twist Bioscience's Shares Buyback Ratio % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Twist Bioscience Shares Buyback Ratio % Chart

Twist Bioscience Annual Data
Trend Sep16 Sep17 Sep18 Sep19 Sep20 Sep21 Sep22 Sep23 Sep24 Sep25
Shares Buyback Ratio %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -9.80 -14.19 -1.83 -2.29 -2.98

Twist Bioscience Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Shares Buyback Ratio % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -0.53 -0.76 -1.06 -1.44 -0.84
TWST
64GF Score
Twist Bioscience Corp TWST
Shares Buyback Ratio % is just one metric. See GF Score™, valuation, warning signs, and more.
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Twist Bioscience Shares Buyback Ratio % Calculation

Twist Bioscience's Shares Buyback Ratio for the fiscal year that ended in Sep. 2025 is calculated as

Shares Buyback Ratio=(Shares Outstanding (EOP) (A: Sep. 2024 ) - Shares Outstanding (EOP) (A: Sep. 2025 )) / Shares Outstanding (EOP) (A: Sep. 2024 )
=(58.877 - 60.631) / 58.877
=-2.98%

Twist Bioscience's Shares Buyback Ratio for the quarter that ended in Jun. 2026 is calculated as

Shares Buyback Ratio=(Shares Outstanding (EOP) (A: Mar. 2026 ) - Shares Outstanding (EOP) (A: Jun. 2026 )) / Shares Outstanding (EOP) (A: Mar. 2026 )
=(62.154 - 62.674) / 62.154
=-0.84%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Shares Buyback Ratio % →
What does a Shares Buyback Ratio % of -4.15 mean?
Twist Bioscience (TWST) has a Shares Buyback Ratio % of -4.15 as of Sep. 13, 2026. Share buyback ratio is the percent change of a company's shares outstanding from two periods. View historical data on Twist Bioscience and its competitors.
Is Twist Bioscience's Shares Buyback Ratio % too high?
Twist Bioscience's current Shares Buyback Ratio % is -4.15. Overall, Twist Bioscience has a GF Score™ of 64/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Twist Bioscience's Shares Buyback Ratio % compare to QGEN and RDNT?
Twist Bioscience's Shares Buyback Ratio % of -4.15 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Shares Buyback Ratio % for a Biotechnology company?
A good Shares Buyback Ratio % depends on the Biotechnology industry context. However, Shares Buyback Ratio % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Shares Buyback Ratio % mean?
A high Shares Buyback Ratio % can signal that a stock is expensive relative to its fundamentals. Share buyback ratio is the percent change of a company's shares outstanding from two periods. View historical data on Twist Bioscience and its competitors. Twist Bioscience's current Shares Buyback Ratio % is -4.15. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Twist Bioscience stock overvalued right now?
Based on GuruFocus' analysis, Twist Bioscience (TWST) is currently considered Significantly Overvalued. The stock's GF Value™ is $53.22, compared to a current price of $127.07 — trading 138.8% above its estimated fair value. The current Shares Buyback Ratio % is -4.15. Twist Bioscience's overall GF Score™ is 64/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Shares Buyback Ratio % calculated?
Shares Buyback Ratio % is calculated from a company's financial statements. For Twist Bioscience (TWST), the current Shares Buyback Ratio % is -4.15 as of Sep. 13, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Twist Bioscience (TWST) Overvalued in 2026?

Based on GuruFocus' analysis, Twist Bioscience stock appears to be overvalued. The current stock price of $127.07 is trading 138.8% above its estimated GF Value™ of $53.22. GuruFocus considers Twist Bioscience to be Significantly Overvalued.

Key valuation signals for TWST:

  • Shares Buyback Ratio %: -4.15
  • GF Value™: $53.22 vs. price of $127.07 (138.8% above fair value)
  • GF Score™: 64/100 with 2 warning signs

No single metric tells the full story. See the TWST stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

Twist Bioscience Business Description

Other Exchanges 1TWST:Italy0ME:Germany
Address 681 Gateway Boulevard, South San Francisco, CA, USA, 94080
Twist Bioscience Corp is a synthetic biology company that has developed a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's proprietary semiconductor-based manufacturing process synthesizes DNA on silicon rather than traditional plastic plates, enabling the production of high-quality synthetic DNA faster, more affordably, and at scale. This platform overcomes conventional inefficiencies, supports cost-effective, high-throughput synthesis, and allows researchers to accelerate innovation. Geographically, the company operates across the Americas, EMEA, and APAC, deriving the majority of its revenue from the Americas.
64GF Score

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Shares Buyback Ratio % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$127.07
Price
$53.22
GF Value